| Entry |
|
|---|
| Name |
Tecarfarin sodium (USAN) |
|---|
| Formula |
C21H13F6O5. Na
|
|---|
| Exact mass |
482.0565
|
|---|
| Mol weight |
482.3051
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Blood modifier agent
DG01950 Antithrombotic agent
DG01708 Coumarin anticoagulant
DG01760 Warfarin and analog
|
|---|
| Remark |
|
|---|
| Efficacy |
Anticoagulant |
|---|
| Comment |
Coumarin derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa00130 | Ubiquinone and other terpenoid-quinone biosynthesis |
|
|---|
| Interaction |
|
|---|
| Brite |
Drug groups [BR:br08330]
Blood modifier agent
DG01950 Antithrombotic agent
DG01708 Coumarin anticoagulant
DG01760 Warfarin and analog
DG01390 Tecarfarin
D09677 Tecarfarin sodium
Target-based classification of drugs [BR:br08310]
Enzymes
Oxidoreductases (EC1)
Vitamin-K-epoxide reductase
VKORC1
D09677 Tecarfarin sodium (USAN)
Drug groups [BR:br08330]
Blood modifier agent
DG01950 Antithrombotic agent
DG01708 Coumarin anticoagulant
DG01760 Warfarin and analog
DG01390 Tecarfarin
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 33
1 C8x C 15.6100 -25.9000
2 C8x C 15.6100 -27.3000
3 C8x C 16.8000 -28.0000
4 C8y C 17.9900 -27.3000
5 C8y C 17.9900 -25.9000
6 C8x C 16.8000 -25.2000
7 C8y C 19.2500 -28.0000
8 C8y C 20.4400 -27.3000
9 C8y C 20.4400 -25.9000
10 O7x O 19.2500 -25.2000
11 C1b C 21.6300 -28.0000
12 C8y C 22.8200 -27.3000
13 C8x C 24.0800 -28.0000
14 C8x C 25.2700 -27.3000
15 C8y C 25.2700 -25.9000
16 C8x C 24.0800 -25.2000
17 C8x C 22.8200 -25.9000
18 C7a C 26.4600 -25.2000
19 O7a O 27.7200 -25.9000
20 C1d C 28.9100 -25.2000
21 O6a O 26.4600 -23.8000
22 C1d C 28.9100 -23.8000
23 X F 30.1000 -23.1000
24 X F 27.6500 -23.1000
25 X F 28.9100 -22.4000
26 C1d C 30.3100 -25.2000
27 C1a C 28.9100 -26.6000
28 X F 31.0100 -26.3900
29 X F 31.0100 -24.0100
30 X F 31.7100 -25.2000
31 O6a O 21.6300 -25.2000
32 O1a O 19.2500 -29.4000 #-
33 Z Na 20.8600 -29.4000 #+
BOND 34
1 1 2 1
2 2 3 2
3 3 4 1
4 4 5 2
5 5 6 1
6 1 6 2
7 4 7 1
8 7 8 2
9 8 9 1
10 9 10 1
11 5 10 1
12 8 11 1
13 11 12 1
14 12 13 2
15 13 14 1
16 14 15 2
17 15 16 1
18 16 17 2
19 12 17 1
20 15 18 1
21 18 19 1
22 19 20 1
23 18 21 2
24 20 22 1
25 22 23 1
26 22 24 1
27 22 25 1
28 20 26 1
29 20 27 1
30 26 28 1
31 26 29 1
32 26 30 1
33 9 31 2
34 7 32 1
|
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