KEGG   DRUG: Epoetin epsilonHelp
Entry
D10000                      Drug                                   

Name
Epoetin epsilon (INN);
Epoetin epsilon (genetical recombination) (JAN)
Formula
C809H1301N229O240S5
Exact mass
18224.5242
Mol weight
18235.7015
Sequence
APPRLICDSR VLERYLLEAK EAENITTGCA EHCSLNENIT VPDTKVNFYA WKRMEVGQQA
VEVWQGLALL SEAVLRGQAL LVNSSQPWEP LQLHVDKAVS GLRSLTTLLR ALGAQKEAIS
PPDAASAAPL RTITADTFRK LFRVYSNFLR GKLKLYTGEA CRTGD
(Disulfide bridge:7-161, 29-33)
  Type
Peptide
Remark
ATC code: B03XA01
Chemical structure group: DG00177
Product (DG00177): D03231<JP/US> D03232<JP>
Efficacy
Anti-anemic, Erythropoietin receptor agonist
Comment
See erythropoietin [CPD:C18200] [hsa:2056] [KO:K05437]
Target
EPOR [HSA:2057] [KO:K05079]
  Pathway
hsa04060  Cytokine-cytokine receptor interaction
hsa04630  Jak-STAT signaling pathway
hsa04640  Hematopoietic cell lineage
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 B BLOOD AND BLOOD FORMING ORGANS
  B03 ANTIANEMIC PREPARATIONS
   B03X OTHER ANTIANEMIC PREPARATIONS
    B03XA Other antianemic preparations
     B03XA01 Erythropoietin
      D10000  Epoetin epsilon (INN)
Target-based classification of drugs [BR:br08310]
 Cytokines and receptors
  Cytokine receptors
   CSF and other factor receptors
    EPOR
     D10000  Epoetin epsilon (INN)
BRITE hierarchy
Other DBs
CAS: 154725-65-2
PubChem: 135626721

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