KEGG   DRUG: Fluticasone propionate and formoterol fumarate hydrateHelp
Entry
D10506            Mixture   Drug                                   

Name
Fluticasone propionate and formoterol fumarate hydrate;
Flutiform (TN)
Component
Fluticasone propionate [DR:D01708], Formoterol fumarate hydrate [DR:D05277]
Class
Metabolizing enzyme substrate
 DG02913  CYP3A4 substrate
Remark
Therapeutic category: 2290
ATC code: R03AK11
Product: D10506<JP>
Efficacy
Antiasthmatic
Comment
Fluticasone propionate is primarily metabolized by CYP3A4.
Formoterol is primarily metabolized by UDP-glucuronosyltransferase (UGT).
Metabolism
Enzyme: CYP3A4 [HSA:1576], UGT [KO:K00699]
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 R RESPIRATORY SYSTEM
  R03 DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
   R03A ADRENERGICS, INHALANTS
    R03AK Adrenergics in combination with corticosteroids or other drugs, excl. anticholinergics
     R03AK11 Formoterol and fluticasone
      D10506  Fluticasone propionate and formoterol fumarate hydrate <JP>
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  22  Respiratory organ agents
   229  Miscellaneous
    2290  Miscellaneous
     D10506  Fluticasone propionate and formoterol fumarate hydrate
BRITE hierarchy
Other DBs
PubChem: 172232599

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