KEGG   DRUG: Valaciclovir hydrochloride hydrate
Entry
D10518                      Drug                                   

Name
Valaciclovir hydrochloride hydrate (JAN);
Valaciclovir (TN)
Product
  Generic
Formula
C13H20N6O4. HCl. xH2O
Structure
Simcomp
Class
Antiviral
 DG02840  Herpesvirus DNA polymerase inhibitor
Remark
Therapeutic category: 6250
ATC code: J05AB11
Chemical structure group: DG00647
Product (DG00647): D00398<JP/US> D10518<JP/US>
Efficacy
Antiviral, DNA polymerase inhibitor
Comment
Active form of prodrug: Aciclovir [DR:D00222]
Target
Herpesvirus DNA polymerase [KO:K18964]
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J05 ANTIVIRALS FOR SYSTEMIC USE
   J05A DIRECT ACTING ANTIVIRALS
    J05AB Nucleosides and nucleotides excl. reverse transcriptase inhibitors
     J05AB11 Valaciclovir
      D10518  Valaciclovir hydrochloride hydrate (JAN) <JP/US>
USP drug classification [BR:br08302]
 Antivirals
  Antiherpetic Agents
   Valacyclovir
    D10518  Valaciclovir hydrochloride hydrate (JAN)
Therapeutic category of drugs in Japan [BR:br08301]
 6  Agents against pathologic organisms and parasites
  62  Chemotherapeutics
   625  Antivirals
    6250  Antivirals
     D10518  Valaciclovir hydrochloride hydrate (JAN)
Prodrugs [br08324.html]
 DG00647
Other DBs
PubChem: 172232611
KCF data

ATOM        25
            1   X   Cl   30.1700  -16.1700
            2   N4y N    22.0500  -17.0100
            3   C8y C    23.3100  -16.5200
            4   C8y C    23.3100  -15.1200
            5   N5x N    21.9800  -14.7000
            6   C8x C    21.2100  -15.8900
            7   N5x N    24.5700  -17.2200
            8   C8y C    25.7600  -16.5200
            9   N4x N    25.7600  -15.1200
            10  C8y C    24.5000  -14.3500
            11  O5x O    24.5000  -12.9500
            12  N1a N    27.0200  -17.1500
            13  C1b C    22.0500  -18.4100
            14  O2a O    20.7900  -19.1100
            15  C1b C    19.6000  -18.4100
            16  C1b C    18.4100  -19.1100
            17  O7a O    17.2200  -18.4100
            18  C7a C    15.9600  -19.0400
            19  C1c C    14.7700  -18.4100
            20  C1c C    13.5800  -19.0400
            21  C1a C    12.3900  -18.3400
            22  C1a C    13.5800  -20.5100
            23  O6a O    15.9600  -20.5100
            24  N1a N    14.7700  -17.0100
            25  O0  O    30.1700  -19.9500
BOND        24
            1     2   3 1
            2     3   4 2
            3     4   5 1
            4     5   6 2
            5     2   6 1
            6     3   7 1
            7     7   8 2
            8     8   9 1
            9     9  10 1
            10    4  10 1
            11   10  11 2
            12    8  12 1
            13    2  13 1
            14   13  14 1
            15   14  15 1
            16   15  16 1
            17   16  17 1
            18   17  18 1
            19   18  19 1
            20   19  20 1
            21   20  21 1
            22   20  22 1
            23   18  23 2
            24   19  24 1 #Down
BRACKET     1    28.0000  -20.6500   28.0000  -18.7600
            1    30.8700  -18.7600   30.8700  -20.6500
            1  x
 ORIGINAL  1   25
 REPEAT    1

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