KEGG   DRUG: Clindamycin phosphate hydrate
Entry
D10531                      Drug                                   

Name
Clindamycin phosphate hydrate (JAN)
Formula
C18H34ClN2O8PS. H2O
Exact mass
522.1568
Mol weight
522.9782
Structure
Simcomp
Class
Antibacterial
 DG01578  Lincosamide antibiotic
Remark
ATC code: D10AF01 G01AA10 J01FF01
Chemical structure group: DG00435
Product (DG00435): D01073<JP/US> D01990<US> D02132<JP/US>
Product (mixture): D10602<JP/US> D11084<US>
Efficacy
Antibacterial, Protein biosynthesis inhibitor
Comment
Semisynthetic lincosamide
Active form of prodrug: Clindamycin [DR:D00277]
Target
50S ribosomal subunit
  Pathway
ko03010  Ribosome
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 D DERMATOLOGICALS
  D10 ANTI-ACNE PREPARATIONS
   D10A ANTI-ACNE PREPARATIONS FOR TOPICAL USE
    D10AF Antiinfectives for treatment of acne
     D10AF01 Clindamycin
      D10531  Clindamycin phosphate hydrate (JAN)
 G GENITO URINARY SYSTEM AND SEX HORMONES
  G01 GYNECOLOGICAL ANTIINFECTIVES AND ANTISEPTICS
   G01A ANTIINFECTIVES AND ANTISEPTICS, EXCL. COMBINATIONS WITH CORTICOSTEROIDS
    G01AA Antibiotics
     G01AA10 Clindamycin
      D10531  Clindamycin phosphate hydrate (JAN)
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01F MACROLIDES, LINCOSAMIDES AND STREPTOGRAMINS
    J01FF Lincosamides
     J01FF01 Clindamycin
      D10531  Clindamycin phosphate hydrate (JAN)
Prodrugs [br08324.html]
 DG00435
Other DBs
PubChem: 254741493
KCF data

ATOM        32
            1   C1y C    22.7500  -16.2400
            2   C1y C    22.7500  -17.6400
            3   C1y C    23.9400  -18.3400
            4   C1y C    25.1300  -17.6400
            5   C1y C    25.1300  -16.2400
            6   O2x O    23.9400  -15.5400
            7   S2a S    26.3900  -15.5400
            8   C1a C    26.3900  -14.1400
            9   O2b O    26.3900  -18.3400
            10  O1a O    23.9400  -19.7400
            11  O1a O    21.4900  -18.3400
            12  C1c C    21.4900  -15.5400
            13  N1b N    20.3000  -16.2400
            14  C1c C    21.4900  -14.1400
            15  X   Cl   20.3000  -13.4400
            16  C1a C    22.7500  -13.4400
            17  C5a C    19.1100  -15.5400
            18  C1y C    17.8500  -16.2400
            19  O5a O    19.1100  -14.1400
            20  N1y N    16.7300  -15.4700
            21  C1x C    15.6100  -16.2400
            22  C1y C    16.1000  -17.5700
            23  C1x C    17.4300  -17.5700
            24  C1a C    16.7300  -14.0700
            25  C1b C    15.4000  -18.8300
            26  C1b C    14.0000  -18.8300
            27  C1a C    13.3000  -20.0200
            28  P1b P    27.5800  -17.6400
            29  O1c O    28.7700  -16.9400
            30  O1c O    26.8800  -16.3800
            31  O1c O    28.2800  -18.8300
            32  O0  O    33.2500  -18.7600
BOND        32
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     5   6 1
            6     1   6 1
            7     5   7 1 #Down
            8     7   8 1
            9     4   9 1 #Down
            10    3  10 1 #Up
            11    2  11 1 #Up
            12    1  12 1
            13   12  13 1
            14   12  14 1
            15   14  15 1 #Up
            16   14  16 1
            17   13  17 1
            18   18  17 1 #Down
            19   17  19 2
            20   18  20 1
            21   20  21 1
            22   21  22 1
            23   22  23 1
            24   18  23 1
            25   20  24 1
            26   22  25 1 #Up
            27   25  26 1
            28   26  27 1
            29    9  28 1
            30   28  29 1
            31   28  30 2
            32   28  31 1

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