KEGG   DRUG: Abametapir
Entry
D10687                      Drug                                   
Name
Abametapir (USAN/INN);
Xeglyze (TN)
Product
XEGLYZE (Dr. Reddy's Laboratories)
Formula
C12H12N2
Exact mass
184.1000
Mol weight
184.24
Structure
Class
Metabolizing enzyme substrate
 DG01892  CYP1A2 substrate
Remark
ATC code: P03AX07
Product: D10687<US>
Efficacy
Pediculicide, Metalloproteinase inhibitor
  Disease
Head lice infestation [DS:H01054]
Comment
Treatment of head lice
Metabolism
Enzyme: CYP1A2 [HSA:1544]
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 P ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS
  P03 ECTOPARASITICIDES, INCL. SCABICIDES, INSECTICIDES AND REPELLENTS
   P03A ECTOPARASITICIDES, INCL. SCABICIDES
    P03AX Other ectoparasiticides, incl. scabicides
     P03AX07 Abametapir
      D10687  Abametapir (USAN/INN) <US>
USP drug classification [BR:br08302]
 Dermatological Agents
  Pediculicides/Scabicides
   Abametapir
    D10687  Abametapir (USAN/INN)
Drug groups [BR:br08330]
 Metabolizing enzyme substrate
  DG01892  CYP1A2 substrate
   D10687  Abametapir
New drug approvals in the USA [br08319.html]
 New molecular entities and new therapeutic biological products
  D10687
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D10687
Drug metabolizing enzymes and transporters [br08309.html]
 Drug metabolizing enzymes
  D10687
Other DBs
CAS: 1762-34-1
PubChem: 254741648
PDB-CCD: EI3[PDBj]
KCF data

ATOM        14
            1   C8x C    14.3562  -14.1450
            2   C8x C    12.9562  -14.1367
            3   C8y C    12.2491  -15.3450
            4   C8x C    12.9419  -16.5615
            5   N5x N    14.3419  -16.5698
            6   C8y C    15.0490  -15.3615
            7   C1a C    10.8491  -15.3450
            8   C8y C    16.4490  -15.3615
            9   N5x N    17.1358  -16.5505
            10  C8x C    18.5358  -16.5502
            11  C8y C    19.2355  -15.3376
            12  C8x C    18.5487  -14.1486
            13  C8x C    17.1487  -14.1489
            14  C1a C    20.6355  -15.3376
BOND        15
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     3   7 1
            8     6   8 1
            9     8   9 2
            10    9  10 1
            11   10  11 2
            12   11  12 1
            13   12  13 2
            14    8  13 1
            15   11  14 1

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Ontology (6)   
   KEGG BRITE (6)   
Disease (1)   
   KEGG DISEASE (1)   
Drug (1)   
   KEGG DGROUP (1)   
Chemical substance (2)   
   PubChem (1)   
   PDB-CCD (1)   
All databases (10)   

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