KEGG   DRUG: Glycopyrronium tosylateHelp
Entry
D10939                      Drug                                   

Name
Glycopyrronium tosylate (USAN);
Glycopyrronium tosylate monohydrate;
Qbrexza (TN)
Product
Formula
C19H28NO3. C7H7O3S. H2O
Exact mass
507.2291
Mol weight
507.6395
Structure
Mol fileKCF fileDB search
Remark
ATC code: D11AA01
Chemical structure group: DG02467
Product (DG02467): D00540<JP/US> D10939<US>
Efficacy
Muscarinic acetylcholine receptor antagonist
Comment
Treatment of hyperhidrosis
Target
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04725  Cholinergic synapse
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 D DERMATOLOGICALS
  D11 OTHER DERMATOLOGICAL PREPARATIONS
   D11A OTHER DERMATOLOGICAL PREPARATIONS
    D11AA Antihidrotics
     D11AA01 Glycopyrronium
      D10939  Glycopyrronium tosylate (USAN) <US>
USP drug classification [BR:br08302]
 Dermatological Agents
  Dermatological Agents, Other
   Miscellaneous, dermatological
    Glycopyrronium
     D10939  Glycopyrronium tosylate (USAN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Acetylcholine (muscarinic)
    CHRM
     D10939  Glycopyrronium tosylate (USAN) <US>
BRITE hierarchy
Other DBs
CAS: 1624259-25-1
PubChem: 342581793
ChEMBL: CHEMBL3707243
KCF data Show

ATOM        35
            1   C1d C    16.0531  -16.8474
            2   C7a C    14.9201  -17.4847
            3   O7a O    13.7162  -16.8474
            4   O6a O    14.9201  -18.9010
            5   C1y C    12.4415  -17.5556
            6   C1x C    11.3628  -16.7766
            7   C1x C    12.0408  -18.9214
            8   N2y N    10.2055  -17.5679 #+
            9   C1x C    10.6793  -18.8818
            10  C1y C    17.2717  -17.5692
            11  C1x C    17.7108  -18.8972
            12  C1x C    19.1120  -18.8938
            13  C1x C    19.5416  -17.5600
            14  C1x C    18.4060  -16.7393
            15  C8y C    16.0531  -15.4311
            16  C8x C    17.2797  -14.7229
            17  C8x C    17.2797  -13.3067
            18  C8x C    16.0531  -12.5985
            19  C8x C    14.8266  -13.3067
            20  C8x C    14.8266  -14.7229
            21  O1a O    17.1381  -15.9976
            22  C1a C     8.9790  -16.8598
            23  C1a C     8.9790  -18.2760
            24  C8x C    22.1903  -16.2402
            25  C8x C    22.1903  -17.6402
            26  C8y C    23.4027  -18.3402
            27  C8x C    24.6152  -17.6402
            28  C8x C    24.6152  -16.2402
            29  C8y C    23.4027  -15.5402
            30  C1a C    23.4027  -19.7400
            31  S4a S    23.4027  -14.1404
            32  O1d O    23.4027  -12.7404 #-
            33  O1d O    24.8027  -14.1404
            34  O1d O    22.0027  -14.1404
            35  O0  O    28.3504  -16.8002
BOND        36
            1     1   2 1
            2     2   3 1
            3     2   4 2
            4     3   5 1
            5     5   6 1
            6     5   7 1
            7     6   8 1
            8     7   9 1
            9     8   9 1
            10    1  10 1
            11   10  11 1
            12   11  12 1
            13   12  13 1
            14   13  14 1
            15   10  14 1
            16    1  15 1
            17   15  16 1
            18   16  17 2
            19   17  18 1
            20   18  19 2
            21   19  20 1
            22   15  20 2
            23    1  21 1
            24    8  22 1
            25    8  23 1
            26   24  25 2
            27   25  26 1
            28   26  27 2
            29   27  28 1
            30   28  29 2
            31   24  29 1
            32   26  30 1
            33   29  31 1
            34   31  32 1
            35   31  33 2
            36   31  34 2

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