KEGG   DRUG: BlarcamesineHelp
Entry
D11383                      Drug                                   

Name
Blarcamesine (USAN)
Formula
C19H23NO
Exact mass
281.178
Mol weight
281.392
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Remark
Chemical structure group: DG03048
Efficacy
Anti-amnesic, Muscarinic/sigma receptor agonist
Comment
Treatment of Rett syndrome
Target
CHRM [HSA:1128 1129 1131 1132 1133] [KO:K04129 K04130 K04131 K04132 K04133]
SIGMAR1 [HSA:10280] [KO:K20719]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04725  Cholinergic synapse
Brite
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Acetylcholine (muscarinic)
    CHRM
     D11383  Blarcamesine (USAN)
 Transporters
  Other transporters
   Auxiliary transport proteins (TC:8.A)
    SIGMAR1
     D11383  Blarcamesine (USAN)
BRITE hierarchy
Other DBs
CAS: 195615-83-9
PubChem: 384585361
KCF data Show

ATOM        21
            1   C1z C    15.9600  -16.1000
            2   C8y C    17.1500  -16.8000
            3   C8y C    14.7700  -16.8000
            4   C8x C    13.5800  -16.1000
            5   C8x C    12.3200  -16.8000
            6   C8x C    12.3200  -18.2000
            7   C8x C    13.5100  -18.9000
            8   C8x C    14.7700  -18.2000
            9   C8x C    17.1500  -18.2000
            10  C8x C    18.4100  -18.9000
            11  C8x C    19.6000  -18.2000
            12  C8x C    19.6000  -16.8000
            13  C8x C    18.4100  -16.1000
            14  C1x C    15.2600  -13.9300
            15  C1y C    14.8400  -15.1900
            16  O2x O    17.0800  -15.2600
            17  C1x C    16.6600  -13.9300
            18  C1b C    13.4958  -15.5814
            19  N1c N    12.5063  -14.6340
            20  C1a C    11.1851  -15.0190
            21  C1a C    12.8412  -13.2650
BOND        23
            1     1   2 1
            2     1   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     6   7 1
            7     7   8 2
            8     3   8 1
            9     2   9 2
            10    9  10 1
            11   10  11 2
            12   11  12 1
            13   12  13 2
            14    2  13 1
            15   14  15 1
            16   15   1 1
            17    1  16 1
            18   16  17 1
            19   14  17 1
            20   15  18 1
            21   18  19 1
            22   19  20 1
            23   19  21 1

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