KEGG   DRUG: Blarcamesine hydrochlorideHelp
Entry
D11549                      Drug                                   

Name
Blarcamesine hydrochloride (USAN)
Formula
C19H23NO. HCl
Exact mass
317.1546
Mol weight
317.853
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Remark
Chemical structure group: DG03048
Efficacy
Anti-amnesic, Muscarinic/sigma receptor agonist
Comment
Treatment of Rett syndrome
Target
CHRM [HSA:1128 1129 1131 1132 1133] [KO:K04129 K04130 K04131 K04132 K04133]
SIGMAR1 [HSA:10280] [KO:K20719]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04725  Cholinergic synapse
Brite
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Acetylcholine (muscarinic)
    CHRM
     D11549  Blarcamesine hydrochloride (USAN)
 Transporters
  Other transporters
   Auxiliary transport proteins (TC:8.A)
    SIGMAR1
     D11549  Blarcamesine hydrochloride (USAN)
BRITE hierarchy
Other DBs
CAS: 195615-84-0
PubChem: 384585525
KCF data Show

ATOM        22
            1   C1z C    19.2003  -16.1871
            2   C8y C    20.3916  -16.8879
            3   C8y C    18.0091  -16.8879
            4   C8x C    16.8178  -16.1871
            5   C8x C    15.5565  -16.8879
            6   C8x C    15.5565  -18.2894
            7   C8x C    16.7477  -18.9901
            8   C8x C    18.0091  -18.2894
            9   C8x C    20.3916  -18.2894
            10  C8x C    21.6529  -18.9901
            11  C8x C    22.8442  -18.2894
            12  C8x C    22.8442  -16.8879
            13  C8x C    21.6529  -16.1871
            14  C1x C    18.4996  -14.0148
            15  C1y C    18.0791  -15.2762
            16  O2x O    20.3215  -15.3462
            17  C1x C    19.9011  -14.0148
            18  C1b C    16.7477  -15.6966
            19  N1c N    15.7667  -14.7156
            20  C1a C    14.4353  -15.1360
            21  C1a C    16.1171  -13.3842
            22  X   Cl   23.8700  -14.7700
BOND        23
            1     1   2 1
            2     1   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     6   7 1
            7     7   8 2
            8     3   8 1
            9     2   9 2
            10    9  10 1
            11   10  11 2
            12   11  12 1
            13   12  13 2
            14    2  13 1
            15   14  15 1
            16   15   1 1
            17    1  16 1
            18   16  17 1
            19   14  17 1
            20   15  18 1
            21   18  19 1
            22   19  20 1
            23   19  21 1

» Japanese version   » Back

DBGET integrated database retrieval system