KEGG   DRUG: Lorcaserin hydrochloride hemihydrate
Entry
D11566                      Drug                                   
Name
Lorcaserin hydrochloride hemihydrate;
Belviq (TN)
Formula
(C11H14ClN)2. 2HCl. H2O
Exact mass
480.1269
Mol weight
482.3143
Structure
Remark
ATC code: A08AA11
Chemical structure group: DG03052
Efficacy
Appetite suppressant, Serotonin 5-HT2c receptor agonist
Target
HTR2C [HSA:3358] [KO:K04157]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04726  Serotonergic synapse
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A08 ANTIOBESITY PREPARATIONS, EXCL. DIET PRODUCTS
   A08A ANTIOBESITY PREPARATIONS, EXCL. DIET PRODUCTS
    A08AA Centrally acting antiobesity products
     A08AA11 Lorcaserin
      D11566  Lorcaserin hydrochloride hemihydrate
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Serotonin
    HTR2C
     D11566  Lorcaserin hydrochloride hemihydrate
Other DBs
CAS: 856681-05-5
PubChem: 384585541
KCF data

ATOM        29
            1   C1x C    18.3400  -18.8300
            2   C1y C    17.5000  -17.7100
            3   C8y C    17.8500  -16.3100
            4   C8y C    19.1100  -15.7500
            5   N1x N    19.8100  -18.8300
            6   C1x C    20.3700  -16.3800
            7   C1x C    20.6500  -17.7800
            8   C1a C    16.1700  -18.1300
            9   C8x C    19.1100  -14.3500
            10  C8x C    17.9200  -13.6500
            11  C8y C    16.7300  -14.3500
            12  X   Cl   15.5400  -13.6500
            13  C8x C    16.7300  -15.7500
            14  X   Cl   23.7300  -15.8900
            15  X   Cl   23.7300  -17.3600
            16  O0  O    24.2200  -13.7200
            17  C1x C    18.3400  -18.8300
            18  N1x N    19.8100  -18.8300
            19  C1x C    20.6500  -17.7800
            20  C1x C    20.3700  -16.3800
            21  C8y C    19.1100  -15.7500
            22  C8y C    17.8500  -16.3100
            23  C1y C    17.5000  -17.7100
            24  C1a C    16.1700  -18.1300
            25  C8x C    16.7300  -15.7500
            26  C8y C    16.7300  -14.3500
            27  C8x C    17.9200  -13.6500
            28  C8x C    19.1100  -14.3500
            29  X   Cl   15.5400  -13.6500
BOND        28
            1     3   4 1
            2     1   5 1
            3     4   6 1
            4     2   3 1
            5     5   7 1
            6     1   2 1
            7     6   7 1
            8     2   8 1 #Down
            9     4   9 2
            10    9  10 1
            11   10  11 2
            12   11  12 1
            13   11  13 1
            14    3  13 2
            15   22  21 1
            16   17  18 1
            17   21  20 1
            18   23  22 1
            19   18  19 1
            20   17  23 1
            21   20  19 1
            22   23  24 1 #Down
            23   21  28 2
            24   28  27 1
            25   27  26 2
            26   26  29 1
            27   26  25 1
            28   22  25 2
BRACKET     1    13.4400  -20.3700   13.4400  -11.9700
            1    21.2100  -11.9700   21.2100  -20.3700
            1  2
 ORIGINAL  1    1   5   7   6   4   3   2   8  13  11  10   9  12
 REPEAT    1   17  18  19  20  21  22  23  24  25  26  27  28  29

» Japanese version   » Back

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Drug (1)   
   KEGG DGROUP (1)   
Chemical substance (1)   
   PubChem (1)   
Gene (2)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
All databases (6)   

Download RDF
DBGET integrated database retrieval system