KEGG   DRUG: ナプロキセンHelp
エントリ  
D00118                      Drug                                   

一般名   
ナプロキセン (JP17);
Naproxen (JP17/USP/INN)
商品名   
米国の商品 
  後発品
NAPROXEN (A-S Medication Solutions), NAPROXEN (A-S Medication Solutions), NAPROXEN (A-S Medication Solutions), NAPROXEN (A-S Medication Solutions), NAPROXEN (A-S Medication Solutions), NAPROXEN (A-S Medication Solutions), NAPROXEN (A-S Medication Solutions), NAPROXEN (A-S Medication Solutions), NAPROXEN (A-S Medication Solutions), NAPROXEN (A-S Medication Solutions), NAPROXEN (Aidarex Pharmaceuticals LLC), NAPROXEN (Aidarex Pharmaceuticals LLC), NAPROXEN (Aidarex Pharmaceuticals LLC), NAPROXEN (Aidarex Pharmaceuticals LLC), NAPROXEN (Aidarex Pharmaceuticals LLC), NAPROXEN (Aidarex Pharmaceuticals LLC), NAPROXEN (American Health Packaging), NAPROXEN (Amneal Pharmaceuticals LLC), NAPROXEN (Amneal Pharmaceuticals of New York LLC), NAPROXEN (Aphena Pharma Solutions - Tennessee), NAPROXEN (Aphena Pharma Solutions - Tennessee), NAPROXEN (Aphena Pharma Solutions - Tennessee), NAPROXEN (Aphena Pharma Solutions - Tennessee), NAPROXEN (Apotheca), NAPROXEN (Apotheca), NAPROXEN (Aurobindo Pharma Limited), NAPROXEN (AvKARE), NAPROXEN (AvKARE), NAPROXEN (AvPAK), NAPROXEN (Avera McKennan Hospital), NAPROXEN (Biomes Pharmaceuticals), NAPROXEN (Blenheim Pharmacal), NAPROXEN (Blenheim Pharmacal), NAPROXEN (Blenheim Pharmacal), NAPROXEN (Blenheim Pharmacal), NAPROXEN (Blenheim Pharmacal), NAPROXEN (Blenheim Pharmacal), NAPROXEN (Blenheim Pharmacal), NAPROXEN (Blenheim Pharmacal), NAPROXEN (Blenheim Pharmacal), NAPROXEN (Bryant Ranch Prepack), NAPROXEN (Bryant Ranch Prepack), NAPROXEN (Bryant Ranch Prepack), NAPROXEN (Bryant Ranch Prepack), NAPROXEN (Bryant Ranch Prepack), NAPROXEN (Bryant Ranch Prepack), NAPROXEN (Bryant Ranch Prepack), NAPROXEN (Bryant Ranch Prepack), NAPROXEN (Cadila Healthcare Limited), NAPROXEN (Camber Pharmaceuticals), NAPROXEN (Camber Pharmaceuticals), NAPROXEN (Carilion Materials Management), NAPROXEN (Carilion Materials Management), NAPROXEN (Carilion Materials Management), NAPROXEN (Cipla USA), NAPROXEN (Cipla USA), NAPROXEN (Citron Pharma LLC), NAPROXEN (Clinical Solutions Wholesale), NAPROXEN (Contract Pharmacy Services-PA), NAPROXEN (DIRECT RX), NAPROXEN (DIRECT RX), NAPROXEN (Denton Pharma), NAPROXEN (Direct RX), NAPROXEN (DirectRX), NAPROXEN (Dispensing Solutions), NAPROXEN (Dispensing Solutions), NAPROXEN (Exelan Pharmaceuticals), NAPROXEN (H.J. Harkins Company), NAPROXEN (H.J. Harkins Company), NAPROXEN (H.J. Harkins Company.), NAPROXEN (KAISER FOUNDATION HOSPITALS), NAPROXEN (Keltman Pharmaceuticals), NAPROXEN (Lake Erie Medical & Surgical Supply DBA Quality Care Products LLC), NAPROXEN (Lake Erie Medical DBA Quality Care Products LLC), NAPROXEN (Lake Erie Medical DBA Quality Care Products LLC), NAPROXEN (Lake Erie Medical DBA Quality Care Products LLC), NAPROXEN (Lake Erie Medical DBA Quality Care Products LLC), NAPROXEN (Lake Erie Medical DBA Quality Care Products LLC), NAPROXEN (Liberty Pharmaceuticals), NAPROXEN (Liberty Pharmaceuticals), NAPROXEN (Life Line Home Care Services), NAPROXEN (MARKSANS PHARMA LIMITED), NAPROXEN (MAS MANAGEMENT GROUP), NAPROXEN (McKesson Corporation), NAPROXEN (Medsource Pharmaceuticals), NAPROXEN (NCS HealthCare of KY), NAPROXEN (NCS HealthCare of KY), NAPROXEN (NCS HealthCare of KY), NAPROXEN (NCS HealthCare of KY), NAPROXEN (Northwind Pharmaceuticals), NAPROXEN (NuCare Pharmaceuticals), NAPROXEN (NuCare Pharmaceuticals), NAPROXEN (NuCare Pharmaceuticals), NAPROXEN (NuCare Pharmaceuticals), NAPROXEN (NuCare Pharmaceuticals), NAPROXEN (NuCare Pharmaceuticals), NAPROXEN (NuCare Pharmaceuticals), NAPROXEN (NuCare Pharmaceuticals), NAPROXEN (NuCare Pharmaceuticals), NAPROXEN (NuCare Pharmaceuticals), NAPROXEN (NuCare Pharmaceuticals), NAPROXEN (NuCare Pharmaceuticals), NAPROXEN (NuCare Pharmaceuticals), NAPROXEN (NuCare Pharmaceuticals), NAPROXEN (PD-Rx Pharmaceuticals), NAPROXEN (PD-Rx Pharmaceuticals), NAPROXEN (PD-Rx Pharmaceuticals), NAPROXEN (PD-Rx Pharmaceuticals), NAPROXEN (PD-Rx Pharmaceuticals), COMFORT PAC WITH NAPROXEN (PD-Rx Pharmaceuticals), NAPROXEN (PD-Rx Pharmaceuticals), NAPROXEN (PD-Rx Pharmaceuticals), NAPROXEN (Palmetto Pharmaceuticals), NAPROXEN (Polygen Pharmaceuticals LLC), NAPROXEN (Preferred Pharmaceuticals), NAPROXEN (Preferred Pharmaceuticals), NAPROXEN (Preferred Pharmaceuticals), NAPROXEN (Preferred Pharmaceuticals), NAPROXEN (Preferred Pharmaceuticals), NAPROXEN (Preferred Pharmaceuticals), NAPROXEN (Preferred Pharmaceuticals), NAPROXEN (Preferred Pharmaceuticals), NAPROXEN (Preferred Pharmaceuticals), NAPROXEN (Preferred Pharmaceuticals), NAPROXEN (Proficient Rx LP), NAPROXEN (Proficient Rx LP), NAPROXEN (Proficient Rx LP), NAPROXEN (Proficient Rx LP), NAPROXEN (Proficient Rx LP), NAPROXEN (QPharma), NAPROXEN (QPharma), NAPROXEN (QPharma), NAPROXEN (QPharma), NAPROXEN (REMEDYREPACK), NAPROXEN (REMEDYREPACK), NAPROXEN (REMEDYREPACK), NAPROXEN (REMEDYREPACK), NAPROXEN (REMEDYREPACK), NAPROXEN (REMEDYREPACK), NAPROXEN (REMEDYREPACK), NAPROXEN (REMEDYREPACK), NAPROXEN (REMEDYREPACK), NAPROXEN (REMEDYREPACK), NAPROXEN (REMEDYREPACK), NAPROXEN (REMEDYREPACK), NAPROXEN (RPK Pharmaceuticals), NAPROXEN (RPK Pharmaceuticals), NAPROXEN (RPK Pharmaceuticals), NAPROXEN (Rebel Distributors Corp), NAPROXEN (Rebel Distributors Corp), NAPROXEN (Rebel Distributors Corp), NAPROXEN (Rebel Distributors Corp.), NAPROXEN (RedPharm Drug), NAPROXEN (RedPharm Drug), NAPROXEN (RedPharm Drug), NAPROXEN (RedPharm Drug), NAPROXEN (RedPharm Drug), NAPROXEN (RedPharm Drug), SALLUS PAIN RELIEF COLLECTION WITH NAPROXEN (Sallus Laboratories), NAPROXEN (St. Mary's Medical Park Pharmacy), NAPROXEN (St. Mary's Medical Park Pharmacy), NAPROXEN (St. Mary's Medical Park Pharmacy), NAPROXEN (State of Florida DOH Central Pharmacy), NAPROXEN (State of Florida DOH Central Pharmacy), NAPROXEN (State of Florida DOH Central Pharmacy), NAPROXEN (State of Florida DOH Central Pharmacy), NAPROXEN (TIME CAP LABORATORIES), NAPROXEN (Teva Pharmaceuticals USA), NAPROXEN (Unit Dose Services), NAPROXEN (Unit Dose Services), NAPROXEN (Unit Dose Services), NAPROXEN (Unit Dose Services), NAPROXEN (Unit Dose Services), NAPROXEN (West-Ward Pharmaceuticals Corp), NAPROXEN (Zydus Pharmaceuticals (USA)), NAPROXEN (medsource pharmaceuticals), NAPROXEN (medsource pharmaceuticals), NAPROXEN (medsource pharmaceuticals), NAPROXEN DELAYED RELEASE (Northwind Pharmaceuticals), NAPROXEN (DIRECT RX), NAPROXEN SODIUM (Northwind Pharmaceuticals)
組成式   
C14H14O3
質量    
230.0943
分子量   
230.2592
構造式   
Mol fileKCF fileDB search
Simcomp    SIMCOMP
クラス   
抗炎症薬
 DG01908  プロピオン酸系抗炎症薬
 DG01504  非ステロイド性抗炎症薬 (NSAID)
  DG01908  プロピオン酸系抗炎症薬
コード   
同一コード: C01517
薬効分類: 1149
ATCコード: G02CC02 M01AE02 M02AA12
化学構造グループ: DG00455
商品 (DG00455): D00118<JP/US> D00970<US>
効能    
鎮痛薬, 抗炎症薬, 解熱薬, シクロオキシゲナーゼ阻害薬
  疾患
関節リウマチ [DS:H00630]
痛風発作 [DS:H01532]
強直性脊椎炎 [DS:H01674]
帯状疱疹 [DS:H00366]
コメント  
プロピオン酸誘導体
ターゲット 
PTGS1 (COX1) [HSA:5742] [KO:K00509]
PTGS2 (COX2) [HSA:5743] [KO:K11987]
  パスウェイ
hsa00590  アラキドン酸の代謝
相互作用  
Drug interaction
構造マップ 
map07048  抗片頭痛薬
map07114  ナフタレンファミリー
map07219  シクロオキシナーゼ (COX) 阻害薬
階層分類  
医療用医薬品の薬効分類 [BR:jp08301]
 1  神経系及び感覚器官用医薬品
  11  中枢神経系用薬
   114  解熱鎮痛消炎剤
    1149  その他の解熱鎮痛消炎剤
     D00118  ナプロキセン (JP17)
医療用医薬品のATC分類 [BR:jp08303]
 G 泌尿生殖器系と性ホルモン
  G02 その他の婦人科用薬
   G02C その他の婦人科用薬
    G02CC 膣内投与用抗炎症製剤
     G02CC02 ナプロキセン
      D00118  ナプロキセン (JP17) <JP/US>
 M 筋骨格系
  M01 抗炎症及び抗リウマチ製剤
   M01A 抗炎症及び抗リウマチ製剤、非ステロイド系
    M01AE プロピオン酸誘導体
     M01AE02 ナプロキセン
      D00118  ナプロキセン (JP17) <JP/US>
  M02 関節・筋肉痛用局所薬剤
   M02A 関節・筋肉痛用局所薬剤
    M02AA 抗炎症製剤、局所用非ステロイド系
     M02AA12 ナプロキセン
      D00118  ナプロキセン (JP17) <JP/US>
医療用医薬品のUSP分類 [BR:jp08302]
 鎮痛薬
  非ステロイド系抗炎症薬
   ナプロキセン
    D00118  ナプロキセン (JP17)
 抗炎症薬
  非ステロイド系抗炎症薬
   ナプロキセン
    D00118  ナプロキセン (JP17)
日本薬局方収載医薬品 [BR:jp08311]
 化学薬品等
  D00118  ナプロキセン
Target-based classification of drugs  [BR:br08310]
 Enzymes
  Oxidoreductases (EC1)
   Prostaglandin synthase
    PTGS1 (COX1)
     D00118  Naproxen (JP17/USP/INN) <JP/US>
    PTGS2 (COX2)
     D00118  Naproxen (JP17/USP/INN) <JP/US>
治療薬の医薬品クラス [jp08360.html]
 リウマチ・痛風治療薬
  D00118
 麻酔薬・鎮痛薬と抗炎症薬
  D00118
BRITE hierarchy
リンク   
CAS: 22204-53-1
PubChem: 7847186
ChEBI: 7476
ChEMBL: CHEMBL154
DrugBank: DB00788
PDB-CCD: NPS[PDBj]
LigandBox: D00118
日化辞: J9.289D

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