KEGG   DRUG: アルプラゾラムHelp
エントリ  
D00225                      Drug                                   

一般名   
アルプラゾラム (JP17);
Alprazolam (JP17/USP/INN)
商品名   
  後発品
米国の商品 
  後発品
ALPRAZOLAM (A-S Medication Solutions), ALPRAZOLAM (APOTHECA), ALPRAZOLAM (Actavis Pharma), ALPRAZOLAM (Actavis Pharma), ALPRAZOLAM (Actavis Pharma), ALPRAZOLAM (Aidarex Pharmaceuticals LLC), ALPRAZOLAM (Aidarex Pharmaceuticals LLC), ALPRAZOLAM (American Health Packaging), ALPRAZOLAM (American Health Packaging), ALPRAZOLAM (Amneal Pharmaceuticals), ALPRAZOLAM (Aphena Pharma Solutions - Tennessee), ALPRAZOLAM (Aphena Pharma Solutions - Tennessee), ALPRAZOLAM (Aphena Pharma Solutions - Tennessee), ALPRAZOLAM (Aphena Pharma Solutions - Tennessee), ALPRAZOLAM (Aphena Pharma Solutions - Tennessee), ALPRAZOLAM (Apotheca), ALPRAZOLAM (Aurobindo Pharma Limited), ALPRAZOLAM (Aurobindo Pharma Limited), ALPRAZOLAM (Bionpharma), ALPRAZOLAM (Blenheim Pharmacal), ALPRAZOLAM (Blenheim Pharmacal), ALPRAZOLAM (Blenheim Pharmacal), ALPRAZOLAM (Blenheim Pharmacal), ALPRAZOLAM (Blenheim Pharmacal), ALPRAZOLAM (Breckenridge Pharmaceutical), ALPRAZOLAM (Bryant Ranch Prepack), ALPRAZOLAM (Bryant Ranch Prepack), ALPRAZOLAM (Bryant Ranch Prepack), ALPRAZOLAM (Bryant Ranch Prepack), ALPRAZOLAM (Bryant Ranch Prepack), ALPRAZOLAM (Bryant Ranch Prepack), ALPRAZOLAM (Bryant Ranch Prepack), ALPRAZOLAM (Bryant Ranch Prepack), ALPRAZOLAM (Bryant Ranch Prepack), ALPRAZOLAM (Bryant Ranch Prepack), ALPRAZOLAM (Bryant Ranch Prepack), ALPRAZOLAM (Bryant Ranch Prepack), ALPRAZOLAM (Cardinal Health), ALPRAZOLAM (Cardinal Health), ALPRAZOLAM (Cardinal Health), ALPRAZOLAM (Contract Pharmacy Services-PA), ALPRAZOLAM (Contract Pharmacy Services-PA), ALPRAZOLAM (Contract Pharmacy Services-PA), XANAX (DIRECT RX), ALPRAZOLAM (DIRECT RX), ALPRAZOLAM (DIRECT RX), ALPRAZOLAM (DIRECT RX), ALPRAZOLAM (Direct Rx), ALPRAZOLAM (DirectRX), ALPRAZOLAM (Dispensing Solutions), ALPRAZOLAM (Golden State Medical Supply), ALPRAZOLAM (Greenstone LLC), ALPRAZOLAM (Greenstone LLC), ALPRAZOLAM (H.J. Harkins Company), ALPRAZOLAM (H.J. Harkins Company), ALPRAZOLAM (Lake Erie Medical & Surgical Supply DBA Quality Care Products LLC), ALPRAZOLAM (Lake Erie Medical & Surgical Supply DBA Quality Care Products LLC), ALPRAZOLAM (Lake Erie Medical DBA Quality Care Products LLC), ALPRAZOLAM (Lake Erie Medical DBA Quality Care Products LLC), ALPRAZOLAM (Lake Erie Medical DBA Quality Care Products LLC), ALPRAZOLAM (Lake Erie Medical DBA Quality Care Products LLC), ALPRAZOLAM (Lake Erie Medical DBA Quality Care Products LLC), ALPRAZOLAM (Lake Erie Medical DBA Quality Care Products LLC), ALPRAZOLAM (Lake Erie Medical DBA Quality Care Products LLC), ALPRAZOLAM (Lake Erie Medical DBA Quality Care Products LLC), ALPRAZOLAM (Lake Erie Medical DBA Quality Care Products LLC), ALPRAZOLAM (Life Line Home Care Services), ALPRAZOLAM (Major Pharmaceuticals), ALPRAZOLAM (McKesson Corporation), ALPRAZOLAM (Medsource Pharmaceuticals), ALPRAZOLAM (Medsource Pharmaceuticals), ALPRAZOLAM (Medsource Pharmaceuticals), ALPRAZOLAM (Medsource Pharmaceuticals), ALPRAZOLAM (Medsource Pharmaceuticals), ALPRAZOLAM (Mylan Institutional), ALPRAZOLAM (Mylan Pharmaceuticals), ALPRAZOLAM (NCS HealthCare of KY), ALPRAZOLAM (NCS HealthCare of KY), ALPRAZOLAM (NCS HealthCare of KY), ALPRAZOLAM (NCS HealthCare of KY), ALPRAZOLAM (NuCare Pharmaceuticals), ALPRAZOLAM (NuCare Pharmaceuticals), ALPRAZOLAM (NuCare Pharmaceuticals), ALPRAZOLAM (NuCare Pharmaceuticals), ALPRAZOLAM (NuCare Pharmaceuticals), ALPRAZOLAM (NuCare Pharmaceuticals), ALPRAZOLAM (NuCare Pharmaceuticals), ALPRAZOLAM (NuCare Pharmaceuticals), ALPRAZOLAM (NuCare Pharmaceuticals), ALPRAZOLAM (NuCare Pharmaceuticals), ALPRAZOLAM (NuCare Pharmaceuticals), ALPRAZOLAM (NuCare Pharmaceuticals), ALPRAZOLAM (NuCare Pharmaceuticals), ALPRAZOLAM (NuCare Pharmaceuticals), ALPRAZOLAM (NuCare Pharmaceuticals), ALPRAZOLAM (PD-Rx Pharmaceuticals), ALPRAZOLAM (PD-Rx Pharmaceuticals), ALPRAZOLAM (PD-Rx Pharmaceuticals), ALPRAZOLAM (PD-Rx Pharmaceuticals), ALPRAZOLAM (PD-Rx Pharmaceuticals), ALPRAZOLAM (PD-Rx Pharmaceuticals), ALPRAZOLAM (PD-Rx Pharmaceuticals), ALPRAZOLAM (Par Pharmaceutical), ALPRAZOLAM (Par Pharmaceutical), ALPRAZOLAM (Preferred Pharmaceuticals), ALPRAZOLAM (Preferred Pharmaceuticals), ALPRAZOLAM (Preferred Pharmaceuticals), ALPRAZOLAM (Preferred Pharmaceuticals), ALPRAZOLAM (Preferred Pharmaceuticals), ALPRAZOLAM (Preferred Pharmaceuticals), ALPRAZOLAM (Preferred Pharmaceuticals), ALPRAZOLAM (Preferred Pharmaceuticals), ALPRAZOLAM (Preferred Pharmaceuticals), ALPRAZOLAM (Proficient Rx LP), ALPRAZOLAM (Proficient Rx LP), ALPRAZOLAM (Proficient Rx LP), ALPRAZOLAM (Proficient Rx LP), ALPRAZOLAM (Proficient Rx LP), ALPRAZOLAM (Proficient Rx LP), ALPRAZOLAM (Proficient Rx LP), ALPRAZOLAM (Proficient Rx LP), ALPRAZOLAM (Quality Care Products), ALPRAZOLAM (REMEDYREPACK), ALPRAZOLAM (REMEDYREPACK), ALPRAZOLAM (RPK Pharmaceuticals), ALPRAZOLAM (RPK Pharmaceuticals), ALPRAZOLAM (RPK Pharmaceuticals), ALPRAZOLAM (Rebel Distributors Corp), ALPRAZOLAM (Rebel Distributors Corp), ALPRAZOLAM (Rebel Distributors Corp.), ALPRAZOLAM (Rebel Distributors Corp.), ALPRAZOLAM (RedPharm), ALPRAZOLAM (RedPharm Drug), ALPRAZOLAM (RedPharm Drug), ALPRAZOLAM (RedPharm Drug), ALPRAZOLAM (RedPharm Drug), ALPRAZOLAM (RedPharm Drug), ALPRAZOLAM (RedPharm Drug), ALPRAZOLAM (Rising Pharmaceuticals), ALPRAZOLAM (Sandoz), ALPRAZOLAM (St. Marys Medical Park Pharmacy), ALPRAZOLAM (TYA Pharmaceuticals), ALPRAZOLAM (Unit Dose Services), ALPRAZOLAM (Unit Dose Services), ALPRAZOLAM (West-Ward Pharmaceuticals Corp.)
組成式   
C17H13ClN4
質量    
308.0829
分子量   
308.7649
構造式   
Mol fileKCF fileDB search
Simcomp    SIMCOMP
クラス   
精神神経系用薬
 DG01567  GABA-A受容体作動薬
 DG01914  ベンゾジアゼピン系抗不安薬
代謝酵素基質薬
 DG01633  CYP3A基質薬
コード   
同一コード: C06817
薬効分類: 1124
ATCコード: N05BA12
商品: D00225<JP/US>
効能    
抗不安薬, マイナートランキライザー, 催眠鎮静薬
  疾患
胃・十二指腸潰瘍 [DS:H01634]
過敏性腸症候群 [DS:H01615]
コメント  
ベンゾジアゼピン誘導体
ターゲット 
  パスウェイ
hsa04080  神経刺激性リガンドとレセプターの相互作用
hsa04727  GABA作動性シナプス
代謝    
Enzyme: CYP3A [HSA:1576 1577 1551]
相互作用  
Drug interaction
構造マップ 
map07030  抗不安薬
map07230  GABA-A受容体の作動薬と拮抗薬
階層分類  
医療用医薬品の薬効分類 [BR:jp08301]
 1  神経系及び感覚器官用医薬品
  11  中枢神経系用薬
   112  催眠鎮静剤、抗不安剤
    1124  ベンゾジアゼピン系製剤
     D00225  アルプラゾラム (JP17)
医療用医薬品のATC分類 [BR:jp08303]
 N 神経系
  N05 精神抑制薬
   N05B 抗不安薬
    N05BA ベンゾジアゼピン誘導体
     N05BA12 アルプラゾラム
      D00225  アルプラゾラム (JP17) <JP/US>
医療用医薬品のUSP分類 [BR:jp08302]
 抗不安薬
  ベンゾジアゼピン
   アルプラゾラム
    D00225  アルプラゾラム (JP17)
日本薬局方収載医薬品 [BR:jp08311]
 化学薬品等
  D00225  アルプラゾラム
Target-based classification of drugs  [BR:br08310]
 Ion channels
  Ligand-gated ion channels
   GABA (ionotropic)
    GABR
     D00225  Alprazolam (JP17/USP/INN) <JP/US>
治療薬の医薬品クラス [jp08360.html]
 精神性疾患薬
  D00225
BRITE hierarchy
リンク   
CAS: 28981-97-7
PubChem: 7847292
ChEBI: 2611
ChEMBL: CHEMBL661
DrugBank: DB00404
PDB-CCD: 08H[PDBj]
LigandBox: D00225
日化辞: J9.279G

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