KEGG   DRUG: クロルタリドンHelp
エントリ  
D00272                      Drug                                   

一般名   
クロルタリドン (JAN);
Chlorthalidone (USP);
Chlortalidone (JAN/INN)
米国の商品 
  後発品
CHLORTHALIDONE (A-S Medication Solutions), CHLORTHALIDONE (A-S Medication Solutions), CHLORTHALIDONE (A-S Medication Solutions), CHLORTHALIDONE (American Health Packaging), CHLORTHALIDONE (Aphena Pharma Solutions - Tennessee), CHLORTHALIDONE (Aphena Pharma Solutions - Tennessee), CHLORTHALIDONE (Aphena Pharma Solutions - Tennessee), CHLORTHALIDONE (Appco Pharma LLC), CHLORTHALIDONE (Bryant Ranch Prepack), CHLORTHALIDONE (Bryant Ranch Prepack), CHLORTHALIDONE (Bryant Ranch Prepack), CHLORTHALIDONE (Bryant Ranch Prepack), CHLORTHALIDONE (Carilion Materials Management), CHLORTHALIDONE (Dr. Reddy's Laboratories), CHLORTHALIDONE (Lake Erie Medical DBA Quality Care Products LLC), CHLORTHALIDONE (Lake Erie Medical DBA Quality Care Products LLC), CHLORTHALIDONE (Mylan Institutional), CHLORTHALIDONE (Mylan Pharmaceuticals), CHLORTHALIDONE (NIVAGEN PHARMACEUTICALS), CHLORTHALIDONE (Northstar Rx LLC), CHLORTHALIDONE (NuCare Pharmaceuticals), CHLORTHALIDONE (NuCare Pharmaceuticals), CHLORTHALIDONE (NuCare Pharmaceuticals), CHLORTHALIDONE (PD-Rx Pharmaceuticals), CHLORTHALIDONE (Preferred Pharmaceuticals), CHLORTHALIDONE (REMEDYREPACK), CHLORTHALIDONE (REMEDYREPACK), CHLORTHALIDONE (REMEDYREPACK), CHLORTHALIDONE (RPK Pharmaceuticals), CHLORTHALIDONE (Rebel Distributors Corp), CHLORTHALIDONE (Rising Pharmaceuticals), CHLORTHALIDONE (Sun Pharmaceutical Industries)
組成式   
C14H11ClN2O4S
質量    
338.0128
分子量   
338.7661
構造式   
Mol fileKCF fileDB search
クラス   
循環器系用薬
 DG01690  スルホンアミド系利尿薬
コード   
ATCコード: C03BA04
商品: D00272<US>
商品 (mixture): D10589<US> D10592<US>
効能    
血圧降下薬, 利尿薬, Na+-Cl-再吸収阻害薬
コメント  
スルホンアミド誘導体
ターゲット 
SLC12A3 (TSC) [HSA:6559] [KO:K14426]
SLC12A1 (NKCC2) [HSA:6557] [KO:K14425]
相互作用  
Drug interaction
構造マップ 
map07017  スルホンアミド誘導体 - 利尿剤
map07233  イオントランスポーター阻害薬
階層分類  
医療用医薬品のATC分類 [BR:jp08303]
 C 循環器系
  C03 利尿薬
   C03B 低許容値の利尿薬、チアジドを除く
    C03BA スルホンアミド、単剤
     C03BA04 クロルタリドン
      D00272  クロルタリドン (JAN) <US>
医療用医薬品のUSP分類 [BR:jp08302]
 心血管治療薬
  チアジド系利尿薬
   クロルタリドン
    D00272  クロルタリドン (JAN)
Target-based classification of drugs  [BR:br08310]
 Transporters
  Solute carrier family
   SLC12
    SLC12A1 (NKCC2)
     D00272  Chlorthalidone (USP) <US>
    SLC12A3 (TSC)
     D00272  Chlorthalidone (USP) <US>
治療薬の医薬品クラス [jp08360.html]
 循環器用薬
  D00272
BRITE hierarchy
リンク   
CAS: 77-36-1
PubChem: 7847338
ChEBI: 3654
ChEMBL: CHEMBL1055
DrugBank: DB00310
LigandBox: D00272
日化辞: J1.476A

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