KEGG   DRUG: ジアゼパムHelp
エントリ  
D00293                      Drug                                   

一般名   
ジアゼパム (JP17);
Diazepam (JP17/USP/INN)
商品名   
  後発品
米国の商品 
  後発品
DIAZEPAM (A-S Medication Solutions), DIAZEPAM (A-S Medication Solutions), DIAZEPAM (A-S Medication Solutions), DIAZEPAM (A-S Medication Solutions), DIAZEPAM (A-S Medication Solutions), DIAZEPAM (A-S Medication Solutions), DIAZEPAM (A-S Medication Solutions), DIAZEPAM (Aidarex Pharmaceuticals LLC), DIAZEPAM (Aidarex Pharmaceuticals LLC), DIAZEPAM (Aphena Pharma Solutions - Tennessee), DIAZEPAM (Aphena Pharma Solutions - Tennessee), DIAZEPAM (Aphena Pharma Solutions - Tennessee), DIAZEPAM (Aphena Pharma Solutions - Tennessee), DIAZEPAM (Aphena Pharma Solutions - Tennessee), DIAZEPAM (Aphena Pharma Solutions - Tennessee), DIAZEPAM (Aphena Pharma Solutions - Tennessee), DIAZEPAM (Aphena Pharma Solutions - Tennessee), DIAZEPAM (Apotheca), DIAZEPAM (Atlantic Biologicals Corps), DIAZEPAM (Blenheim Pharmacal), DIAZEPAM (Bryant Ranch Prepack), DIAZEPAM (Bryant Ranch Prepack), DIAZEPAM (Bryant Ranch Prepack), DIAZEPAM (Bryant Ranch Prepack), DIAZEPAM (Cardinal Health), DIAZEPAM (Cardinal Health), DIAZEPAM (Cardinal Health), DIAZEPAM (Cardinal Health), DIAZEPAM (Contract Pharmacy Services-PA), DIAZEPAM (Contract Pharmacy Services-PA), DIAZEPAM (Contract Pharmacy Services-PA), DIAZEPAM (DIRECT RX), DIAZEPAM (DIRECT RX), DIAZEPAM (DIRECT RX), DIAZEPAM (DIRECT RX), DIAZEPAM (Direct Rx), DIAZEPAM (Dispensing Solutions), DIAZEPAM (Dispensing Solutions), DIAZEPAM (Dispensing Solutions), DIAZEPAM (General Injectables and Vaccines), DIAZEPAM (General Injectables and Vaccines), DIAZEPAM (H.J. Harkins Company), DIAZEPAM (Hospira), DIAZEPAM (Hospira), DIAZEPAM (Hospira), DIAZEPAM (Lake Erie Medical & Surgical Supply DBA Quality Care Products LLC), DIAZEPAM (Lake Erie Medical DBA Quality Care Products LLC), DIAZEPAM (Lake Erie Medical DBA Quality Care Products LLC), DIAZEPAM (Lannett Company), DIAZEPAM (Major Pharmaceuticals), DIAZEPAM (Mayne Pharma), DIAZEPAM (McKesson Corporation), DIAZEPAM (Medsource Pharmaceuticals), DIAZEPAM (Medsource Pharmaceuticals), DIAZEPAM (Mylan Institutional), DIAZEPAM (Mylan Pharmaceuticals), DIAZEPAM (NCS HealthCare of KY), DIAZEPAM (NCS HealthCare of KY), DIAZEPAM (NuCare Pharmaceuticals), DIAZEPAM (NuCare Pharmaceuticals), DIAZEPAM (NuCare Pharmaceuticals), DIAZEPAM (NuCare Pharmaceuticals), DIAZEPAM (NuCare Pharmaceuticals), DIAZEPAM (NuCare Pharmaceuticals), DIAZEPAM (NuCare Pharmaceuticals), DIAZEPAM (Oceanside Pharmaceuticals), DIAZEPAM (PD-Rx Pharmaceuticals), DIAZEPAM (PD-Rx Pharmaceuticals), DIAZEPAM (PD-Rx Pharmaceuticals), DIAZEPAM (PD-Rx Pharmaceuticals), DIAZEPAM (PD-Rx Pharmaceuticals), DIAZEPAM (Precision Dose), DIAZEPAM (Preferred Pharmaceuticals), DIAZEPAM (Preferred Pharmaceuticals), DIAZEPAM (Preferred Pharmaceuticals), DIAZEPAM (Preferred Pharmaceuticals), DIAZEPAM (Preferred Pharmaceuticals), DIAZEPAM (Proficient Rx LP), DIAZEPAM (Proficient Rx LP), DIAZEPAM (Proficient Rx LP), DIAZEPAM (Proficient Rx LP), DIAZEPAM (Proficient Rx LP), DIAZEPAM (Qualitest Pharmaceuticals), DIAZEPAM (REMEDYREPACK), DIAZEPAM (REMEDYREPACK), DIAZEPAM (REMEDYREPACK), DIAZEPAM (REMEDYREPACK), DIAZEPAM (RPK Pharmaceuticals), DIAZEPAM (Rebel Distributors Corp), DIAZEPAM (Rebel Distributors Corp.), DIAZEPAM (RedPharm Drug), DIAZEPAM (RedPharm Drug), DIAZEPAM (RedPharm Drug), DIAZEPAM (Redpharm Drug), DIAZEPAM (St. Mary's Medical Park Pharmacy), DIAZEPAM (TYA Pharmaceuticals), DIAZEPAM (TYA Pharmaceuticals), DIAZEPAM (Teva Pharmaceuticals USA), DIAZEPAM (Teva Pharmaceuticals USA), DIAZEPAM (Unit Dose Services), DIAZEPAM (Unit Dose Services), DIAZEPAM (Unit Dose Services), DIAZEPAM INTENSOL (West-Ward Pharmaceuticals Corp.)
組成式   
C16H13ClN2O
質量    
284.0716
分子量   
284.7402
構造式   
Mol fileKCF fileDB search
Simcomp    SIMCOMP
クラス   
精神神経系用薬
 DG01567  GABA-A受容体作動薬
 DG01914  ベンゾジアゼピン系抗不安薬
酵素基質
 DG01639  CYP2C19により代謝される薬剤
 DG01633  CYP3Aにより代謝される薬剤
コード   
同一コード: C06948
薬効分類: 1124 1139
ATCコード: N05BA01
商品: D00293<JP/US>
効能    
抗不安薬, マイナートランキライザー, 催眠鎮静薬
  疾患
神経症における不安・緊張・抑うつ [DS:H01662]
うつ病における不安・緊張 [DS:H01646]
熱性けいれん [DS:H00783]
コメント  
ベンゾジアゼピン誘導体
ターゲット 
  パスウェイ
hsa04080  神経刺激性リガンドとレセプターの相互作用
hsa04727  GABA作動性シナプス
代謝    
Enzyme: CYP2C19 [HSA:1557], CYP3A4 [HSA:1576]
相互作用  
Drug interaction
構造マップ 
map07030  抗不安薬
map07032  催眠薬
map07033  抗痙攣薬
map07117  ベンゾジアゼピンファミリー
map07230  GABA-A受容体の作動薬と拮抗薬
階層分類  
医療用医薬品の薬効分類 [BR:jp08301]
 1  神経系及び感覚器官用医薬品
  11  中枢神経系用薬
   112  催眠鎮静剤、抗不安剤
    1124  ベンゾジアゼピン系製剤
     D00293  ジアゼパム (JP17)
   113  抗てんかん剤
    1139  その他の抗てんかん剤
     D00293  ジアゼパム (JP17)
医療用医薬品のATC分類 [BR:jp08303]
 N 神経系
  N05 精神抑制薬
   N05B 抗不安薬
    N05BA ベンゾジアゼピン誘導体
     N05BA01 ジアゼパム
      D00293  ジアゼパム (JP17) <JP/US>
医療用医薬品のUSP分類 [BR:jp08302]
 抗けいれん薬
  ガンマアミノ酪酸(GABA)増強剤
   ジアゼパム
    D00293  ジアゼパム (JP17)
 抗不安薬
  ベンゾジアゼピン
   ジアゼパム
    D00293  ジアゼパム (JP17)
日本薬局方収載医薬品 [BR:jp08311]
 化学薬品等
  D00293  ジアゼパム
  D00293  ジアゼパム錠
Target-based classification of drugs  [BR:br08310]
 Ion channels
  Ligand-gated ion channels
   GABA (ionotropic)
    GABR
     D00293  Diazepam (JP17/USP/INN) <JP/US>
治療薬の医薬品クラス [jp08360.html]
 精神性疾患薬
  D00293
BRITE hierarchy
リンク   
CAS: 439-14-5
PubChem: 7847359
ChEBI: 49575
ChEMBL: CHEMBL12
DrugBank: DB00829
PDB-CCD: DZP[PDBj]
LigandBox: D00293
日化辞: J2.044C

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