KEGG   DRUG: ジゴキシンHelp
エントリ  
D00298                      Drug                                   

一般名   
ジゴキシン (JP17);
Digoxin (JP17/USP)
商品名   
米国の商品 
  後発品
DIGOX (Aidarex Pharmaceuticals LLC), DIGOXIN (American Health Packaging), DIGOXIN (Bryant Ranch Prepack), DIGOXIN (Bryant Ranch Prepack), DIGOXIN (Bryant Ranch Prepack), DIGOXIN (Cardinal Health), DIGOXIN (Cardinal Health), DIGOX (Carilion Materials Management), DIGOX (Carilion Materials Management), DIGOXIN (Clinical Solutions Wholesale), DIGOXIN (DEPT HEALTH CENTRAL PHARMACY), DIGOXIN (General Injectables and Vaccines), DIGOXIN (Golden State Medical Supply), DIGOXIN (HF Acquisition Co LLC), DIGOXIN (Impax Generics), DIGOXIN (Jerome Stevens Pharmaceuticals), DIGOX (Lake Erie Medical DBA Quality Care Products LLC), DIGOX (Lannett Company), DIGOXIN (Major Pharmaceuticals), DIGITEK (Mylan Institutional), DIGITEK (Mylan Pharmaceuticals), DIGOXIN (NCS HealthCare of KY), DIGOXIN (NCS HealthCare of KY), DIGOXIN (NCS HealthCare of KY), DIGOXIN (NCS HealthCare of KY), DIGOXIN (NCS HealthCare of KY), DIGOXIN (Northstar Rx LLC), DIGOXIN (Northwind Pharmaceuticals), DIGOXIN (Northwind Pharmaceuticals), DIGOXIN (NuCare Pharmaceuticals), DIGOXIN (NuCare Pharmaceuticals), DIGOXIN (NuCare Pharmaceuticals), DIGOXIN (NuCare Pharmaceuticals), DIGOXIN (NuCare Pharmaceuticals), DIGOXIN (NuCare Pharmaceuticals), DIGOXIN (PD-Rx Pharmaceuticals), DIGOX (PD-Rx Pharmaceuticals), DIGOXIN (Par Pharmaceutical), DIGOX (Proficient Rx LP), DIGOXIN (REMEDYREPACK), DIGOXIN (REMEDYREPACK), DIGOXIN (REMEDYREPACK), DIGOXIN (REMEDYREPACK), DIGOXIN (REMEDYREPACK), DIGOXIN (REMEDYREPACK), DIGOXIN (Sandoz), DIGOXIN (State of Florida DOH Central Pharmacy), DIGOXIN (State of Florida DOH Central Pharmacy), DIGOXIN (State of Florida DOH Central Pharmacy), DIGOXIN (State of Florida DOH Central Pharmacy), DIGOXIN (Sun Pharmaceutical Industries), DIGOX (TYA Pharmaceuticals), DIGOXIN (Unit Dose Services), DIGOXIN (Unit Dose Services), DIGOXIN (West-Ward Pharmaceuticals Corp), DIGOXIN (West-Ward Pharmaceuticals Corp.), DIGOXIN (West-Ward Pharmaceuticals Corp.)
組成式   
C41H64O14
質量    
780.4296
分子量   
780.9385
構造式   
Mol fileKCF fileDB search
Simcomp    SIMCOMP
クラス   
循環器系用薬
 DG01703  強心薬
  DG01698  強心配糖体
   DG01697  ジギタリス強心配糖体
 DG01653  抗不整脈薬
トランスポーター基質
 DG01665  ABCB1 (P糖蛋白質) により代謝される薬剤
コード   
同一コード: C06956
薬効分類: 2113
ATCコード: C01AA05
商品: D00298<JP/US>
効能    
強心薬
コメント  
ジギタリス配糖体
ターゲット 
ATP1A [HSA:476 477 478 480] [KO:K01539]
  パスウェイ
hsa04260  心筋の収縮
hsa04261  心筋細胞におけるアドレナリンシグナル伝達
代謝    
Transporter: ABCB1 [HSA:5243]
相互作用  
Drug interaction
構造マップ 
map07233  イオントランスポーター阻害薬
他のマップ 
map04976  胆汁の分泌
階層分類  
医療用医薬品の薬効分類 [BR:jp08301]
 2  個々の器官系用医薬品
  21  循環器官用薬
   211  強心剤
    2113  ジギタリス製剤
     D00298  ジゴキシン (JP17)
医療用医薬品のATC分類 [BR:jp08303]
 C 循環器系
  C01 心疾患治療
   C01A 強心配糖体
    C01AA ジギタリス配糖体
     C01AA05 ジゴキシン
      D00298  ジゴキシン (JP17) <JP/US>
医療用医薬品のUSP分類 [BR:jp08302]
 心血管治療薬
  その他心血管治療薬
   ジゴキシン
    D00298  ジゴキシン (JP17)
日本薬局方収載医薬品 [BR:jp08311]
 化学薬品等
  D00298  ジゴキシン
  D00298  ジゴキシン錠
  D00298  ジゴキシン注射液
Target-based classification of drugs  [BR:br08310]
 Enzymes
  Hydrolases (EC3)
   ATPase
    ATP1A
     D00298  Digoxin (JP17/USP) <JP/US>
治療薬の医薬品クラス [jp08360.html]
 循環器用薬
  D00298
BRITE hierarchy
リンク   
CAS: 20830-75-5
PubChem: 7847364
ChEBI: 4551
ChEMBL: CHEMBL1751
DrugBank: DB00390
PDB-CCD: DGX[PDBj]
LigandBox: D00298
日化辞: J4.082G

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