KEGG   DRUG: フィナステリドHelp
エントリ  
D00321                      Drug                                   

一般名   
フィナステリド (JAN);
Finasteride (JAN/USP/INN)
商品名   
米国の商品 
  後発品
FINASTERIDE (Accord Healthcare), FINASTERIDE (Accord Healthcare), FINASTERIDE (Actavis Pharma), FINASTERIDE (Actavis Pharma), FINASTERIDE (Aidarex Pharmaceuticals LLC), FINASTERIDE (American Health Packaging), FINASTERIDE (Ascend Laboratories), FINASTERIDE (Ascend Laboratories), FINASTERIDE (Atlantic Biologicals Corps), FINASTERIDE (Aurobindo Pharma Limited), FINASTERIDE (Aurobindo Pharma Limited), FINASTERIDE (AvKARE), FINASTERIDE (AvPAK), FINASTERIDE (Bryant Ranch Prepack), FINASTERIDE (Bryant Ranch Prepack), FINASTERIDE (Bryant Ranch Prepack), FINASTERIDE (Bryant Ranch Prepack), FINASTERIDE (Burel Pharma), FINASTERIDE (Cadila Healthcare Limited), FINASTERIDE (Camber Pharmaceuticals), FINASTERIDE (Camber Pharmaceuticals), FINASTERIDE (Camber Pharmaceuticals), FINASTERIDE (Cardinal Health), FINASTERIDE (Cipla USA), FINASTERIDE (Contract Pharmacy Services-PA), FINASTERIDE (Dr Reddys Laboratories), FINASTERIDE (Dr Reddys Laboratories), FINASTERIDE (Dr. Reddy's Laboratories Limited), FINASTERIDE (Dr. Reddy's Laboratories Limited), FINASTERIDE (Exelan Pharmaceuticals), FINASTERIDE (H.J. Harkins Company), FINASTERIDE (Hetero Drugs Limited), FINASTERIDE (Hetero Labs Limited), FINASTERIDE (Hetero Labs Limited), FINASTERIDE (KAISER FOUNDATION HOSPITALS), FINASTERIDE (Lake Erie Medical DBA Quality Care Products LLC), FINASTERIDE (Legacy Pharmaceutical Packaging), FINASTERIDE (McKesson Packaging Services Business Unit of McKesson Corporation), FINASTERIDE (Mylan Institutional), FINASTERIDE (Mylan Pharmaceuticals), FINASTERIDE (New Horizon Rx Group), FINASTERIDE (NuCare Pharmaceuticals), FINASTERIDE (NuCare Pharmaceuticals), FINASTERIDE (NuCare Pharmaceuticals), FINASTERIDE (NuCare Pharmaceuticals), FINASTERIDE (NuCare Pharmaceuticals), FINASTERIDE (NuCare Pharmaceuticals), FINASTERIDE (NuCare Pharmaceuticals), FINASTERIDE (NuCare Pharmaceuticals), FINASTERIDE (NuCare Pharmaceuticals), FINASTERIDE (Preferred Pharmacetucals), FINASTERIDE (Preferred Pharmaceuticals), FINASTERIDE (Preferred Pharmaceuticals), FINASTERIDE (Preferred Pharmaceuticals), FINASTERIDE (Preferred Pharmaceuticals), FINASTERIDE (Proficient Rx LP), FINASTERIDE (Proficient Rx LP), FINASTERIDE (REMEDYREPACK), FINASTERIDE (REMEDYREPACK), FINASTERIDE (Rising Health), FINASTERIDE (Rising Health), FINASTERIDE (Teva Pharmaceuticals USA), FINASTERIDE (Unit Dose Services), FINASTERIDE (Unit Dose Services), FINASTERIDE (Zydus Pharmaceuticals (USA))
組成式   
C23H36N2O2
質量    
372.2777
分子量   
372.5441
構造式   
Mol fileKCF fileDB search
クラス   
酵素基質
 DG01633  CYP3Aにより代謝される薬剤
コード   
薬効分類: 2499
ATCコード: D11AX10 G04CB01
商品: D00321<JP/US>
効能    
抗アンドロゲン薬, 5α還元酵素阻害薬
コメント  
5α-還元酵素II型阻害薬, 男性型脱毛症用薬
ターゲット 
SRD5A2 [HSA:6716] [KO:K12344]
  パスウェイ
hsa00140  ステロイドホルモンの生合成
代謝    
Enzyme: CYP3A4 [HSA:1576]
相互作用  
Drug interaction
階層分類  
医療用医薬品の薬効分類 [BR:jp08301]
 2  個々の器官系用医薬品
  24  ホルモン剤(抗ホルモン剤を含む)
   249  その他のホルモン剤(抗ホルモン剤を含む)
    2499  他に分類されないホルモン剤(抗ホルモン剤を含む)
     D00321  フィナステリド (JAN)
医療用医薬品のATC分類 [BR:jp08303]
 D 皮膚科用薬
  D11 その他の皮膚科用製剤
   D11A その他の皮膚科用製剤
    D11AX その他の皮膚科用製剤
     D11AX10 フィナステリド
      D00321  フィナステリド (JAN) <JP/US>
 G 泌尿生殖器系と性ホルモン
  G04 泌尿器科用薬
   G04C 良性前立腺肥大症用薬
    G04CB テストステロン-5-アルファ還元酵素阻害薬
     G04CB01 フィナステリド
      D00321  フィナステリド (JAN) <JP/US>
医療用医薬品のUSP分類 [BR:jp08302]
 泌尿生殖器薬
  前立腺肥大症治療薬
   フィナステリド
    D00321  フィナステリド (JAN)
Target-based classification of drugs  [BR:br08310]
 Enzymes
  Oxidoreductases (EC1)
   Dehydrogenases
    SRD5A2
     D00321  Finasteride (JAN/USP/INN) <JP/US>
日本の新薬 [jp08318.html]
 新有効成分含有医薬品
  D00321
BRITE hierarchy
リンク   
CAS: 98319-26-7
PubChem: 7847387
ChEBI: 5062
ChEMBL: CHEMBL710
DrugBank: DB01216
PDB-CCD: FIT[PDBj]
LigandBox: D00321
日化辞: J367.472J

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