KEGG   DRUG: フロセミドHelp
エントリ  
D00331                      Drug                                   

一般名   
フロセミド (JP17);
Furosemide (JP17/USP/INN);
Frusemide
商品名   
  後発品
米国の商品 
FUROSEMIDE (A-S Medication Solutions), FUROSEMIDE (Aphena Pharma Solutions - Tennessee), FUROSEMIDE (Aphena Pharma Solutions - Tennessee), FUROSEMIDE (Aphena Pharma Solutions - Tennessee), FUROSEMIDE (Aphena Pharma Solutions - Tennessee), FUROSEMIDE (Bryant Ranch Prepack), FUROSEMIDE (Cardinal Health), FUROSEMIDE (Cardinal Health), FUROSEMIDE (Cardinal Health), FUROSEMIDE (Cardinal Health), FUROSEMIDE (Contract Pharmacy Services-PA), FUROSEMIDE (Contract Pharmacy Services-PA), FUROSEMIDE (Fresenius Kabi USA), FUROSEMIDE (Fresenius Kabi USA), FUROSEMIDE (General Injectables & Vaccines), FUROSEMIDE (Golden State Medical Supply), FUROSEMIDE (HF Acquisition Co LLC), FUROSEMIDE (HF Acquisition Co LLC), FUROSEMIDE (HF Acquisition Co LLC), FUROSEMIDE (Hospira), FUROSEMIDE (Hospira), FUROSEMIDE (Lake Erie Medical DBA Quality Care Products LLC), FUROSEMIDE (Lake Erie Medical DBA Quality Care Products LLC), FUROSEMIDE (Mylan Institutional), FUROSEMIDE (Mylan Pharmaceuticals), FUROSEMIDE (NCS HealthCare of KY), FUROSEMIDE (NCS HealthCare of KY), FUROSEMIDE (NCS HealthCare of KY), FUROSEMIDE (NCS HealthCare of KY), FUROSEMIDE (NuCare Pharmaceuticals), FUROSEMIDE (NuCare Pharmaceuticals), FUROSEMIDE (NuCare Pharmaceuticals), FUROSEMIDE (PD-Rx Pharmaceuticals), FUROSEMIDE (Preferred Pharmaceuticals), FUROSEMIDE (REMEDYREPACK), FUROSEMIDE (REMEDYREPACK), FUROSEMIDE (REMEDYREPACK), FUROSEMIDE (REMEDYREPACK), FUROSEMIDE (REMEDYREPACK), FUROSEMIDE (REMEDYREPACK), FUROSEMIDE (REMEDYREPACK), FUROSEMIDE (REMEDYREPACK), FUROSEMIDE (Safecor Health), FUROSEMIDE (Sandoz), FUROSEMIDE (State of Florida DOH Central Pharmacy), LASIX (Validus Pharmaceuticals LLC), FUROSEMIDE (West-Ward Pharmaceuticals Corp.)
  後発品
FUROSEMIDE (A-S Medication Solutions), FUROSEMIDE (A-S Medication Solutions), FUROSEMIDE (Aidarex Pharmaceuticals LLC), FUROSEMIDE (Aidarex Pharmaceuticals LLC), FUROSEMIDE (Amneal Biosciences), FUROSEMIDE (Aphena Pharma Solutions - Tennessee), FUROSEMIDE (Aphena Pharma Solutions - Tennessee), FUROSEMIDE (Aphena Pharma Solutions - Tennessee), FUROSEMIDE (Aphena Pharma Solutions - Tennessee), FUROSEMIDE (Aphena Pharma Solutions - Tennessee), FUROSEMIDE (Apotheca), FUROSEMIDE (Apotheca), FUROSEMIDE (Atlantic Biologicals Corps), FUROSEMIDE (Atlantic Biologicals Corps), FUROSEMIDE (Baxter Healthcare Corporation), FUROSEMIDE (Blenheim Pharmacal), FUROSEMIDE (Bryant Ranch Prepack), FUROSEMIDE (Bryant Ranch Prepack), FUROSEMIDE (Bryant Ranch Prepack), FUROSEMIDE (Cardinal Health), FUROSEMIDE (Cardinal Health), FUROSEMIDE (Cardinal Health), FUROSEMIDE (Cardinal Health), FUROSEMIDE (Cardinal Health), FUROSEMIDE (Clinical Solutions Wholesale), FUROSEMIDE (Contract Pharmacy Services-PA), FUROSEMIDE (Contract Pharmacy Services-PA), FUROSEMIDE (DIRECT RX), FUROSEMIDE (DIRECT RX), FUROSEMIDE (Excellium Pharmaceutical), FUROSEMIDE (General Injectables & Vaccines), FUROSEMIDE (Heritage Pharmaceuticals), FUROSEMIDE (Heritage Pharmaceuticals), DIASCREEN 12-PANEL MEDICATED COLLECTION SYSTEM (IT3 Medical LLC), FUROSEMIDE (IT3 Medical LLC), FUROSEMIDE (IT3 Medical LLC), TOXYCOLOGY MEDICATED COLLECTION SYSTEM (IT3 Medical LLC), FUROSEMIDE (Lake Erie Medical DBA Quality Care Products LLC), FUROSEMIDE (Lake Erie Medical DBA Quality Care Products LLC), FUROSEMIDE (Lake Erie Medical DBA Quality Care Products LLC), FUROSEMIDE (Leading Pharma), FUROSEMIDE (Mas Management Group), FUROSEMIDE (McKesson Packaging Services a business unit of McKesson Corporation), FUROSEMIDE (MedVantx), FUROSEMIDE (MedVantx), FUROSEMIDE (Medical Purchasing Solutions), FUROSEMIDE (Medical Purchasing Solutions), FUROSEMIDE (Morton Grove Pharmaceuticals), FUROSEMIDE (New Horizon Rx Group), FUROSEMIDE (NuCare Pharmaceuticals), FUROSEMIDE (NuCare Pharmaceuticals), FUROSEMIDE (NuCare Pharmaceuticals), FUROSEMIDE (NuCare Pharmaceuticals), FUROSEMIDE (PD-Rx Pharmaceuticals), FUROSEMIDE (PD-Rx Pharmaceuticals), FUROSEMIDE (PD-Rx Pharmaceuticals), FUROSEMIDE (PD-Rx Pharmaceuticals), FUROSEMIDE (PD-Rx Pharmaceuticals), FUROSEMIDE (Precision Dose), FUROSEMIDE (Precision Dose), FUROSEMIDE (Preferred Pharmaceuticals), LASIX (Preferred Pharmaceuticals), FUROSEMIDE (Preferred Pharmaceuticals), FUROSEMIDE (Preferred Pharmaceuticals), FUROSEMIDE (Preferred Pharmaceuticals), FUROSEMIDE (Preferred Pharmaceuticals), FUROSEMIDE (Preferred Pharmaceuticals), FUROSEMIDE (Proficient Rx LP), FUROSEMIDE (Proficient Rx LP), FUROSEMIDE (Proficient Rx LP), FUROSEMIDE (Proficient Rx LP), FUROSEMIDE (QPharma), FUROSEMIDE (QPharma), FUROSEMIDE (REMEDYREPACK), FUROSEMIDE (REMEDYREPACK), FUROSEMIDE (REMEDYREPACK), FUROSEMIDE (REMEDYREPACK), FUROSEMIDE (REMEDYREPACK), FUROSEMIDE (RPK Pharmaceuticals), FUROSEMIDE (Ranbaxy Pharmaceuticals), FUROSEMIDE (ReadyMeds), FUROSEMIDE (Rebel Distirbutors Corp), FUROSEMIDE (Rebel Distributors Corp), FUROSEMIDE (RedPharm Drug), FUROSEMIDE (RedPharm Drug), FUROSEMIDE (RedPharm Drug), FUROSEMIDE (Solco Healthcare LLC), FUROSEMIDE (St Mary's Medical Park Pharmacy), FUROSEMIDE (St Marys Medical Park Pharmacy), FUROSEMIDE (St. Mary's Medical Park Pharmacy), FUROSEMIDE (St. Mary's Medical Park Pharmacy), FUROSEMIDE (State of Florida DOH Central Pharmacy), FUROSEMIDE (State of Florida DOH Central Pharmacy), FUROSEMIDE (State of Florida DOH Central Pharmacy), FUROSEMIDE (TYA Pharmaceuticals), FUROSEMIDE (Unit Dose Services), FUROSEMIDE (Unit Dose Services), FUROSEMIDE (Wockhardt USA LLC.)
組成式   
C12H11ClN2O5S
質量    
330.0077
分子量   
330.7441
構造式   
Mol fileKCF fileDB search
Simcomp    SIMCOMP
クラス   
循環器系用薬
 DG01690  スルホンアミド系利尿薬
  DG01747  フロセミド系利尿薬
 DG01748  ループ利尿薬
  DG01747  フロセミド系利尿薬
トランスポーター基質
 DG02859  SLC22A6 (OAT1) により代謝される薬剤
 DG02860  SLC22A8 (OAT3) により代謝される薬剤
コード   
同一コード: C07017
薬効分類: 2139 2149
ATCコード: C03CA01
化学構造グループ: DG00272
商品 (DG00272): D00331<JP/US>
効能    
利尿薬, Na-K-Cl共輸送体阻害薬
  疾患
本態性高血圧症 [DS:H01633]
高血圧症 [DS:H01633]
コメント  
ループ利尿薬
スルホンアミド誘導体
ターゲット 
SLC12A1 (NKCC2) [HSA:6557] [KO:K14425]
SLC12A2 (NKCC1) [HSA:6558] [KO:K10951]
代謝    
Transporter: SLC22A6 [HSA:9356], SLC22A8 [HSA:9376], ABCC4 [HSA:10257]
相互作用  
Drug interaction
構造マップ 
map07017  スルホンアミド誘導体 - 利尿剤
map07055  スルホンアミド誘導体 - 構造展開
map07233  イオントランスポーター阻害薬
他のマップ 
map04976  胆汁の分泌
階層分類  
医療用医薬品の薬効分類 [BR:jp08301]
 2  個々の器官系用医薬品
  21  循環器官用薬
   213  利尿剤
    2139  その他の利尿剤
     D00331  フロセミド (JP17)
   214  血圧降下剤
    2149  その他の血圧降下剤
     D00331  フロセミド (JP17)
医療用医薬品のATC分類 [BR:jp08303]
 C 循環器系
  C03 利尿薬
   C03C 高許容値の利尿薬
    C03CA スルホンアミド、単剤
     C03CA01 フロセミド
      D00331  フロセミド (JP17) <JP/US>
医療用医薬品のUSP分類 [BR:jp08302]
 心血管治療薬
  ループ利尿薬
   フロセミド
    D00331  フロセミド (JP17)
日本薬局方収載医薬品 [BR:jp08311]
 化学薬品等
  D00331  フロセミド
  D00331  フロセミド錠
  D00331  フロセミド注射液
Target-based classification of drugs  [BR:br08310]
 Transporters
  Solute carrier family
   SLC12
    SLC12A1 (NKCC2)
     D00331  Furosemide (JP17/USP/INN) <JP/US>
    SLC12A2 (NKCC1)
     D00331  Furosemide (JP17/USP/INN) <JP/US>
治療薬の医薬品クラス [jp08360.html]
 循環器用薬
  D00331
BRITE hierarchy
リンク   
CAS: 54-31-9
PubChem: 7847397
ChEBI: 47426
ChEMBL: CHEMBL35
DrugBank: DB00695
PDB-CCD: FUN[PDBj]
LigandBox: D00331
日化辞: J1.913E

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