KEGG   DRUG: ニフェジピンHelp
エントリ  
D00437                      Drug                                   

一般名   
ニフェジピン (JP17);
Nifedipine (JP17/USP/INN)
商品名   
  後発品
カサンミル (全星薬品工業), カサンミル (全星薬品工業), セパミット (日本ジェネリック), ニフェジピン (ニプロ), ニフェジピン (三和化学研究所), ニフェジピン (三和化学研究所), ニフェジピン (全星薬品工業), ニフェジピン (全星薬品工業), ニフェジピン (共和薬品工業), ニフェジピン (日医工), ニフェジピン (日医工), ニフェジピン (東和薬品), ニフェジピン (東和薬品), ニフェジピン (東和薬品), ニフェジピン (東洋カプセル), ニフェジピン (東洋カプセル), ニフェジピン (武田テバ薬品), ニフェジピン (沢井製薬), ニフェジピン (沢井製薬), ニフェジピン (沢井製薬), ニフェジピン (沢井製薬), ニフェジピン (鶴原製薬), ニフェジピン (鶴原製薬), ニフェランタン (全星薬品工業), ニフェランタン (全星薬品工業), ニフェランタン (全星薬品工業), ヘルラート (京都薬品工業)
Similar product
米国の商品 
  後発品
NIFEDIPINE (A-S Medication Solutions), NIFEDIPINE (A-S Medication Solutions), NIFEDIPINE (Actavis Pharma), NIFEDIPINE (Actavis Pharma), AFEDITAB (Actavis Pharma), NIFEDIPINE (Aidarex Pharmaceuticals LLC), NIFEDICALXL (Aidarex Pharmaceuticals LLC), NIFEDIPINE (Alvogen), NIFEDIPINE (American Health Packaging), NIFEDIPINE (American Health Packaging), NIFEDIPINE (American Health Packaging), NIFEDIPINE (Aphena Pharma Solutions - Tennessee), AFEDITAB (Aphena Pharma Solutions - Tennessee), NIFEDIPINE (Aphena Pharma Solutions - Tennessee), NIFEDIPINE (Aphena Pharma Solutions - Tennessee), NIFEDIPINE (Aphena Pharma Solutions - Tennessee), NIFEDIPINE (Aphena Pharma Solutions - Tennessee), NIFEDIPINE (Aphena Pharma Solutions - Tennessee), NIFEDIPINE (AvPAK), NIFEDIPINE (AvPAK), NIFEDIPINE (Bryant Ranch Prepack), NIFEDICAL (Bryant Ranch Prepack), NIFEDIPINE (Bryant Ranch Prepack), NIFEDIPINE (Bryant Ranch Prepack), NIFEDIPINE (Cadila Healthcare Limited), NIFEDIPINE (Cadila Healthcare Limited), NIFEDICAL (Cardinal Health), NIFEDIPINE (Cardinal Health), NIFEDIPINE (Cardinal Health), NIFEDIPINE (Cardinal Health), AFEDITAB (Carilion Materials Management), NIFEDIPINE (Carilion Materials Management), NIFEDIPINE (DIRECT RX), NIFEDIPINE (DIRECT RX), NIFEDIPINE (Dispensing Solutions), NIFEDIPINE (Golden State Medical Supply), NIFEDIPINE (Greenstone LLC), NIFEDIPINE (Greenstone LLC), NIFEDIPINE (Heritage Pharmaceuticals), NIFEDIPINE (Ingenus Pharmaceuticals), NIFEDIPINE (Intergel Pharmaceuticals), NIFEDIPINE (International Laboratories), NIFEDIPINE (Kremers Urban Pharmaceuticals), NIFEDIPINE (Lake Erie Medical DBA Quality Care Products LLC), NIFEDIPINE (Lake Erie Medical DBA Quality Care Products LLC), NIFEDIPINE (Lake Erie Medical DBA Quality Care Products LLC), NIFEDIPINE (Lake Erie Medical DBA Quality Care Products LLC), NIFEDIPINE (Lake Erie Medical DBA Quality Care Products LLC), NIFEDIPINE (Leading Pharma), NIFEDIPINE (Leading Pharma), NIFEDIPINE (Legacy Pharmaceutical Packaging), NIFEDIPINE (Lupin Pharmaceuticals), NIFEDIPINE (Major Pharmaceuticals), NIFEDIPINE (Mylan Institutional), NIFEDIPINE (Mylan Pharmaceuticals), NIFEDIPINE (Mylan Pharmaceuticals), NIFEDIPINE (NCS HealthCare of KY), NIFEDIPINE (NuCare Pharmaceuticals), NIFEDIPINE (NuCare Pharmaceuticals), NIFEDIPINE (NuCare Pharmaceuticals), NIFEDIPINE (NuCare Pharmaceuticals), NIFEDIPINE (NuCare Pharmaceuticals), NIFEDIPINE (NuCare Pharmaceuticals), NIFEDIPINE (NuCare Pharmaceuticals), NIFEDIPINE (NuCare Pharmaceuticals), NIFEDIPINE (NuCare Pharmaceuticals), NIFEDIPINE (NuCare Pharmaceuticals), NIFEDIPINE (NuCare Pharmaceuticals), NIFEDIPINE (NuCare Pharmaceuticals), NIFEDIPINE (NuCare Pharmaceuticals), NIFEDIPINE (NuCare Pharmaceuticals), NIFEDIPINE (NuCare Pharmaceuticals), NIFEDIPINE (NuCare Pharmaceuticals), NIFEDIPINE (Oceanside Pharmaceuticals), NIFEDIPINE (Oceanside Pharmaceuticals), NIFEDIPINE (Oceanside Pharmaceuticals), NIFEDIPINE (Oceanside Pharmaceuticals), NIFEDIPINE (PD-Rx Pharmaceuticals), NIFEDIPINE (PD-Rx Pharmaceuticals), NIFEDIPINE (Par Pharmaceutical), NIFEDIPINE (Par Pharmaceutical), NIFEDIPINE (Par Pharmaceutical), NIFEDIPINE (Preferred Pharmaceuticals), NIFEDIPINE (Preferred Pharmaceuticals), NIFEDIPINE (Preferred Pharmaceuticals), NIFEDIPINE (Preferred Pharmaceuticals), NIFEDIPINE (Preferred Pharmaceuticals), NIFEDIPINE (Proficient Rx LP), NIFEDIPINE (REMEDYREPACK), NIFEDIPINE (REMEDYREPACK), NIFEDIPINE (REMEDYREPACK), NIFEDIPINE (REMEDYREPACK), NIFEDIPINE (Rebel Distributors Corp), NIFEDIPINE (Rebel Distributors Corp), NIFEDIPINE (Rebel Distributors Corp), NIFEDIPINE (Rebel Distributors Corp), NIFEDIPINE (RedPharm Drug), NIFEDIAC CC (State of Florida DOH Central Pharmacy), NIFEDIPINE (State of Florida DOH Central Pharmacy), NIFEDIPINE (State of Florida DOH Central Pharmacy), NIFEDICAL (State of Florida DOH Central Pharmacy), NIFEDIPINE (State of Florida DOH Central Pharmacy), NIFEDIAC CC (State of Florida DOH Central Pharmacy), NIFEDIPINE (TWi Pharmaceuticals), NIFEDIPINE (TWi Pharmaceuticals), NIFEDIPINE (TYA Pharmaceuticals), NIFEDIPINE (Unit Dose Services), NIFEDIPINE (Unit Dose Services), NIFEDIPINE (Zydus Pharmaceuticals (USA)), NIFEDIPINE (Zydus Pharmaceuticals (USA)), NIFEDIPINE (bryant ranch prepack)
組成式   
C17H18N2O6
質量    
346.1165
分子量   
346.3346
構造式   
Mol fileKCF fileDB search
Simcomp    SIMCOMP
クラス   
循環器系用薬
 DG01928  ジヒドロピリジン系カルシウム拮抗薬
その他
 DG01575  カルシウムチャネル遮断薬
  DG01496  カルシウムチャネルL型遮断薬
酵素基質
 DG01633  CYP3Aにより代謝される薬剤
コード   
同一コード: C07266
薬効分類: 2171
ATCコード: C08CA05
商品: D00437<JP/US>
効能    
血圧降下薬, 血管拡張薬, カルシウムチャネル遮断薬
  疾患
本態性高血圧症 [DS:H01633]
狭心症 [DS:H01632]
コメント  
ジヒドロピリジン誘導体
ターゲット 
CACNA1-L [HSA:775 776 778 779] [KO:K04850 K04851 K04853 K04857]
  パスウェイ
hsa04020  カルシウムシグナル伝達経路
hsa04260  心筋の収縮
hsa04261  心筋細胞におけるアドレナリンシグナル伝達
hsa04270  血管平滑筋の収縮
代謝    
Enzyme: CYP3A4 [HSA:1576]
相互作用  
Drug interaction
構造マップ 
map07036  カルシウムチャネル遮断薬
階層分類  
医療用医薬品の薬効分類 [BR:jp08301]
 2  個々の器官系用医薬品
  21  循環器官用薬
   217  血管拡張剤
    2171  冠血管拡張剤
     D00437  ニフェジピン (JP17)
医療用医薬品のATC分類 [BR:jp08303]
 C 循環器系
  C08 カルシウムチャネル遮断薬
   C08C 選択的カルシウムチャネル遮断薬、主に血管への効果がある
    C08CA ジヒドロピリジン誘導体
     C08CA05 ニフェジピン
      D00437  ニフェジピン (JP17) <JP/US>
医療用医薬品のUSP分類 [BR:jp08302]
 心血管治療薬
  カルシウムチャネル遮断薬
   ニフェジピン
    D00437  ニフェジピン (JP17)
日本薬局方収載医薬品 [BR:jp08311]
 化学薬品等
  D00437  ニフェジピン
  D00437  ニフェジピン徐放カプセル
  D00437  ニフェジピン細粒
  D00437  ニフェジピン腸溶細粒
Target-based classification of drugs  [BR:br08310]
 Ion channels
  Voltage-gated ion channels
   Calcium channels
    CACNA1-L
     D00437  Nifedipine (JP17/USP/INN) <JP/US>
治療薬の医薬品クラス [jp08360.html]
 循環器用薬
  D00437
BRITE hierarchy
リンク   
CAS: 21829-25-4
PubChem: 7847503
ChEBI: 7565
ChEMBL: CHEMBL193
DrugBank: DB01115
LigandBox: D00437
日化辞: J3.467C

» English version   » Back

DBGET integrated database retrieval system