KEGG   DRUG: ミルタザピンHelp
エントリ  
D00563                      Drug                                   

一般名   
ミルタザピン (JAN);
Mirtazapine (JAN/USAN/INN)
商品名   
  後発品
ミルタザピン (エルメッドエーザイ), ミルタザピン (キョーリンリメディオ), ミルタザピン (ジェイドルフ製薬), ミルタザピン (ダイト), ミルタザピン (ニプロ), ミルタザピン (ニプロ), ミルタザピン (フェルゼンファーマ), ミルタザピン (共創未来ファーマ), ミルタザピン (共和薬品工業), ミルタザピン (大蔵製薬), ミルタザピン (日医工), ミルタザピン (日新製薬-山形), ミルタザピン (日本ケミファ), ミルタザピン (東和薬品), ミルタザピン (東和薬品), ミルタザピン (武田テバファーマ), ミルタザピン (沢井製薬), ミルタザピン (沢井製薬), ミルタザピン (辰巳化学), ミルタザピン (長生堂製薬), ミルタザピン (陽進堂)
Similar product
米国の商品 
  後発品
MIRTAZAPINE (A-S Medication Solutions), MIRTAZAPINE (A-S Medication Solutions), MIRTAZAPINE (Actavis Pharma), MIRTAZAPINE (Actavis Pharma), MIRTAZAPINE (Aidarex Pharmaceuticals LLC), MIRTAZAPINE (Aidarex Pharmaceuticals LLC), MIRTAZAPINE (American Health Packaging), MIRTAZAPINE (Aphena Pharma Solutions - Tennessee), MIRTAZAPINE (Aphena Pharma Solutions - Tennessee), MIRTAZAPINE (Aphena Pharma Solutions - Tennessee), MIRTAZAPINE (Aphena Pharma Solutions - Tennessee), MIRTAZAPINE (Aphena Pharma Solutions - Tennessee), MIRTAZAPINE (Aphena Pharma Solutions - Tennessee), MIRTAZAPINE (Apotex Corp.), MIRTAZAPINE (Aurobindo Pharma Limited), MIRTAZAPINE (Aurobindo Pharma Limited), MIRTAZAPINE (Aurolife Pharma LLC), MIRTAZAPINE (Bryant Ranch Prepack), MIRTAZAPINE (Bryant Ranch Prepack), MIRTAZAPINE (Bryant Ranch Prepack), MIRTAZAPINE (Bryant Ranch Prepack), MIRTAZAPINE (Bryant Ranch Prepack), MIRTAZAPINE (Bryant Ranch Prepack), MIRTAZAPINE (Bryant Ranch Prepack), MIRTAZAPINE (Bryant Ranch Prepack), MIRTAZAPINE (Bryant Ranch Prepack), MIRTAZAPINE (Cadila Healthcare Limited), MIRTAZAPINE (Cardinal Health), MIRTAZAPINE (Cardinal Health), MIRTAZAPINE (Cardinal Health), MIRTAZAPINE (Clinical Solutions Wholesale), MIRTAZAPINE (Clinical Solutions Wholesale), MIRTAZAPINE (Contract Pharmacy Services-PA), MIRTAZAPINE (Contract Pharmacy Services-PA), MIRTAZAPINE (Contract Pharmacy Services-PA), MIRTAZAPINE (DIRECT RX), MIRTAZAPINE (Direct Rx), MIRTAZAPINE (DirectRX), MIRTAZAPINE (Eon Labs), MIRTAZAPINE (H.J. Harkins Company), MIRTAZAPINE (Impax Generics), MIRTAZAPINE (Lake Erie Medical DBA Quality Care Products LLC), MIRTAZAPINE (Lake Erie Medical DBA Quality Care Products LLC), MIRTAZAPINE (Lake Erie Medical Medical DBA Quality Care Products LLC), MIRTAZAPINE (Major Pharmaceuticals), MIRTAZAPINE (McKesson Corporation), MIRTAZAPINE (Medsource Pharmaceuitcals), MIRTAZAPINE (Medsource Pharmaceuticals), MIRTAZAPINE (Mylan Institutional), MIRTAZAPINE (Mylan Pharmaceuticals), MIRTAZAPINE (NCS HealthCare of KY), MIRTAZAPINE (NCS HealthCare of KY), MIRTAZAPINE (NCS HealthCare of KY), MIRTAZAPINE (NCS HealthCare of KY), MIRTAZAPINE (Northstar Rx LLC), MIRTAZAPINE (NuCare Pharmaceuticals), MIRTAZAPINE (NuCare Pharmaceuticals), MIRTAZAPINE (NuCare Pharmaceuticals), MIRTAZAPINE (NuCare Pharmaceuticals), MIRTAZAPINE (NuCare Pharmaceuticals), MIRTAZAPINE (NuCare Pharmaceuticals), MIRTAZAPINE (NuCare Pharmaceuticals), MIRTAZAPINE (NuCare Pharmaceuticals), MIRTAZAPINE (PD-Rx Pharmaceuticals), MIRTAZAPINE (PD-Rx Pharmaceuticals), MIRTAZAPINE (Preferred Pharmaceuticals), MIRTAZAPINE (Preferred Pharmaceuticals), MIRTAZAPINE (Preferred Pharmaceuticals), MIRTAZAPINE (Preferred Pharmaceuticals), MIRTAZAPINE (Proficient Rx LP), MIRTAZAPINE (Proficient Rx LP), MIRTAZAPINE (Proficient Rx LP), MIRTAZAPINE (Proficient Rx LP), MIRTAZAPINE (REMEDYREPACK), MIRTAZAPINE (REMEDYREPACK), MIRTAZAPINE (REMEDYREPACK), MIRTAZAPINE (REMEDYREPACK), MIRTAZAPINE (REMEDYREPACK), MIRTAZAPINE (REMEDYREPACK), MIRTAZAPINE (REMEDYREPACK), MIRTAZAPINE (REMEDYREPACK), MIRTAZAPINE (REMEDYREPACK), MIRTAZAPINE (REMEDYREPACK), MIRTAZAPINE (REMEDYREPACK), MIRTAZAPINE (REMEDYREPACK), MIRTAZAPINE (REMEDYREPACK), MIRTAZAPINE (RPK Pharmaceuticals), MIRTAZAPINE (RPK Pharmaceuticals), MIRTAZAPINE (Rebel Distributors Corp), MIRTAZAPINE (Rebel Distributors Corp), MIRTAZAPINE (Rebel Distributors Corp.), MIRTAZAPINE (Rising Health), MIRTAZAPINE (Rising Health), MIRTAZAPINE (State of Florida DOH Central Pharmacy), MIRTAZAPINE (State of Florida DOH Central Pharmacy), MIRTAZAPINE (State of Florida DOH Central Pharmacy), MIRTAZAPINE (State of Florida DOH Central Pharmacy), MIRTAZAPINE (Sun Pharmaceutical Industries), MIRTAZAPINE (TYA Pharmaceuticals), MIRTAZAPINE (TYA Pharmaceuticals), MIRTAZAPINE (TYA Pharmaceuticals), MIRTAZAPINE (Teva Pharmaceuticals USA), MIRTAZAPINE (Unit Dose Services), MIRTAZAPINE (Zydus Pharmaceuticals (USA))
組成式   
C17H19N3
質量    
265.1579
分子量   
265.3529
構造式   
Mol fileKCF fileDB search
Simcomp    SIMCOMP
クラス   
循環器系用薬
 DG01466  アドレナリン受容体拮抗薬
  DG01465  α-アドレナリン受容体拮抗薬
   DG01460  α2-アドレナリン受容体拮抗薬
精神神経系用薬
 DG01729  四環系抗うつ薬
その他
 DG01489  5-HT3-受容体拮抗薬
酵素基質
 DG01892  CYP1A2により代謝される薬剤
 DG01644  CYP2D6により代謝される薬剤
 DG01633  CYP3Aにより代謝される薬剤
コード   
同一コード: C07570
薬効分類: 1179
ATCコード: N06AX11
化学構造グループ: DG02838
商品 (DG02838): D00563<JP/US>
効能    
抗うつ薬, セロトニン受容体拮抗薬
コメント  
ノルアドレナリン・特異的セロトニン作動性抗うつ薬 (NaSSA)
ターゲット 
HTR2 [HSA:3356 3357 3358] [KO:K04157]
HTR3 [HSA:3359 9177 170572 200909 285242] [KO:K04819]
ADRA2 [HSA:150 151 152] [KO:K04138 K04139 K04140]
  パスウェイ
hsa04080  神経刺激性リガンドとレセプターの相互作用
hsa04726  セロトニン作動性シナプス
代謝    
Enzyme: CYP1A2 [HSA:1544], CYP2D6 [HSA:1565], CYP3A4 [HSA:1576]
相互作用  
Drug interaction
構造マップ 
map07027  抗うつ薬
階層分類  
医療用医薬品の薬効分類 [BR:jp08301]
 1  神経系及び感覚器官用医薬品
  11  中枢神経系用薬
   117  精神神経用剤
    1179  その他の精神神経用剤
     D00563  ミルタザピン (JAN)
医療用医薬品のATC分類 [BR:jp08303]
 N 神経系
  N06 精神賦活薬
   N06A 抗うつ薬
    N06AX その他の抗うつ薬
     N06AX11 ミルタザピン
      D00563  ミルタザピン (JAN) <JP/US>
医療用医薬品のUSP分類 [BR:jp08302]
 抗うつ薬
  その他抗うつ薬
   ミルタザピン
    D00563  ミルタザピン (JAN)
Target-based classification of drugs  [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    ADRA2
     D00563  Mirtazapine (JAN/USAN/INN) <JP/US>
   Serotonin
    HTR2
     D00563  Mirtazapine (JAN/USAN/INN) <JP/US>
 Ion channels
  Ligand-gated ion channels
   Serotonin
    HTR3
     D00563  Mirtazapine (JAN/USAN/INN) <JP/US>
治療薬の医薬品クラス [jp08360.html]
 精神性疾患薬
  D00563
日本の新薬 [jp08318.html]
 新有効成分含有医薬品
  D00563
BRITE hierarchy
リンク   
CAS: 85650-52-8
PubChem: 7847629
ChEBI: 6950
ChEMBL: CHEMBL654
DrugBank: DB00370
LigandBox: D00563
日化辞: J327.434I

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