KEGG   DRUG: スマトリプタンコハク酸塩
エントリ  
D00676                      Drug                                   

一般名   
スマトリプタンコハク酸塩 (JAN);
Sumatriptan succinate (JAN/USP)
商品名   
  後発品
米国の商品 
  後発品
SUMATRIPTAN (A-S Medication Solutions), SUMATRIPTAN (AuroMedics Pharma LLC), SUMATRIPTAN (AuroMedics Pharma LLC), SUMATRIPTAN (Golden State Medical Supply), SUMATRIPTAN (Mylan Institutional LLC), SUMATRIPTAN (Mylan Institutional LLC), SUMATRIPTAN (Northstar Rx LLC), SUMATRIPTAN (OrchidPharma), SUMATRIPTAN (Proficient Rx LP), SUMATRIPTAN (Proficient Rx LP), SUMATRIPTAN (Unit Dose Services), SUMATRIPTAN (Unit Dose Services), SUMATRIPTAN (West-Ward Pharmaceuticals Corp), SUMATRIPTAN (A-S Medication Solutions), SUMATRIPTAN (Aurobindo Pharma Limited), SUMATRIPTAN (Bryant Ranch Prepack), SUMATRIPTAN SUCCINATE (Dr. Reddy's Laboratories Limited), SUMATRIPTAN SUCCINATE (Dr. Reddy's Laboratories Limited), SUMATRIPTAN SUCCINATE (Fresenius Kabi USA), SUMATRIPTAN SUCCINATE (GSMS), SUMATRIPTAN (Golden State Medical Supply), SUMATRIPTAN SUCCINATE (Lake Erie Medical DBA Quality Care Products LLC), SUMATRIPTAN SUCCINATE (Lake Erie Medical DBA Quality Care Products LLC), SUMATRIPTAN SUCCINATE (Medsource Pharmaceuticals), SUMATRIPTAN SUCCINATE (Mylan Pharmaceuticals), SUMATRIPTAN (NorthStar Rx LLC), SUMATRIPTAN (NuCare Pharmaceuticals), SUMATRIPTAN SUCCINATE (NuCare Pharmaceuticals), SUMATRIPTAN SUCCINATE (NuCare Pharmaceuticals), SUMATRIPTAN (NuCare Pharmaceuticals), SUMATRIPTAN (NuCare Pharmaceuticals), SUMATRIPTAN SUCCINATE (Preferred Pharmaceuticals), SUMATRIPTAN (Preferred Pharmaceuticals), SUMATRIPTAN (Preferred Pharmaceuticals), SUMATRIPTAN (Preferred Pharmaceuticals), SUMATRIPTAN (Proficient Rx LP), SUMATRIPTAN SUCCINATE (Proficient Rx LP), SUMATRIPTAN SUCCINATE (Proficient Rx LP), SUMATRIPTAN SUCCINATE (Proficient Rx LP), SUMATRIPTAN SUCCINATE (Proficient Rx LP), SUMATRIPTAN (Proficient Rx LP), SUMATRIPTAN SUCCINATE (Proficient Rx LP), SUMATRIPTAN SUCCINATE (Proficient Rx LP), SUMATRIPTAN (Proficient Rx LP), SUMATRIPTAN (Quality Care Products), SUMATRIPTAN SUCCINATE (Quality Care Products), SUMATRIPTAN SUCCINATE (REMEDYREPACK), SUMATRIPTAN (REMEDYREPACK), SUMATRIPTAN SUCCINATE (Sandoz), SUMATRIPTAN SUCCINATE (Sun Pharmaceutical Industries), SUMATRIPTAN SUCCINATE (Sun Pharmaceutical Industries), SUMATRIPTAN (Teva Pharmaceuticals USA), SUMATRIPTAN (Unit Dose Services), SUMATRIPTAN SUCCINATE (Wockhardt USA LLC.), SUMATRIPTAN (NuCare Pharmaceuticals)
組成式   
C14H21N3O2S. C4H6O4
質量    
413.1621
分子量   
413.4885
構造式   
Simcomp   
クラス   
鎮痛薬
 DG01484  5-HT1B-受容体作動薬
 DG01485  5-HT1D-受容体作動薬
 DG01518  5-HT1B/1D受容体作動薬
 DG01943  トリプタン系薬剤
代謝酵素基質薬
 DG02917  MAO基質薬
コード   
薬効分類: 2160
ATCコード: N02CC01
化学構造グループ: DG00836
商品 (DG00836): D00451<JP/US> D00676<JP/US>
商品 (mixture): D11577<US>
効能    
抗片頭痛薬, 血管収縮薬, セロトニン受容体作動薬
  疾患
群発頭痛 [DS:H01588]
コメント  
トリプタン系
5-HT1B/1D受容体作動型片頭痛治療薬
ターゲット 
HTR1B [HSA:3351] [KO:K04153]
HTR1D [HSA:3352] [KO:K04153]
  パスウェイ
hsa04080  神経刺激性リガンドとレセプターの相互作用
hsa04726  セロトニン作動性シナプス
代謝    
Enzyme: MAOA [HSA:4128]
相互作用  

構造マップ 
map07048  抗片頭痛薬
map07211  セロトニン受容体の作動薬と拮抗薬
階層分類  
医療用医薬品の薬効分類 [BR:jp08301]
 2  個々の器官系用医薬品
  21  循環器官用薬
   216  血管収縮剤
    2160  血管収縮剤
     D00676  スマトリプタンコハク酸塩 (JAN)
医療用医薬品のATC分類 [BR:jp08303]
 N 神経系
  N02 鎮痛薬
   N02C 抗片頭痛製剤
    N02CC 選択的セロトニン(5HT1)作動薬
     N02CC01 スマトリプタン
      D00676  スマトリプタンコハク酸塩 (JAN) <JP/US>
医療用医薬品のUSP分類 [BR:jp08302]
 抗片頭痛薬
  セロトニン(5-HT)受容体作動薬
   スマトリプタン
    D00676  スマトリプタンコハク酸塩 (JAN)
ターゲットに基づく医薬品分類 [BR:jp08310]
 Gタンパク質共役受容体
  ロドプシンファミリー
   セロトニン
    HTR1B
     D00676  スマトリプタンコハク酸塩 (JAN) <JP/US>
    HTR1D
     D00676  スマトリプタンコハク酸塩 (JAN) <JP/US>
日本の新薬 [jp08318.html]
 新有効成分含有医薬品
  D00676
薬物代謝酵素とトランスポーター [jp08309.html]
 薬物代謝酵素
  D00676
リンク   
CAS: 103628-48-4
PubChem: 7847742
ChEBI: 64359
ChEMBL: CHEMBL1201150
DrugBank: DB00669
LigandBox: D00676
日化辞: J528.534H

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