KEGG   Danio rerio (zebrafish): 30298
Entry
30298             CDS       T01004                                 
Symbol
jak2b
Name
(RefSeq) tyrosine-protein kinase JAK2
  KO
K04447  Janus kinase 2 [EC:2.7.10.2]
Organism
dre  Danio rerio (zebrafish)
Pathway
dre04148  Efferocytosis
dre04217  Necroptosis
dre04920  Adipocytokine signaling pathway
dre05168  Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:dre00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    30298 (jak2b)
  09143 Cell growth and death
   04217 Necroptosis
    30298 (jak2b)
 09150 Organismal Systems
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    30298 (jak2b)
 09160 Human Diseases
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    30298 (jak2b)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:dre01001]
    30298 (jak2b)
Enzymes [BR:dre01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     30298 (jak2b)
Protein kinases [BR:dre01001]
 Non-receptor tyrosine kinases
  JAK family [OT]
   30298 (jak2b)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase FERM_F2 FERM_F1 Jak1_Phl SH2 FERM_C_FAK1 ABC1 RIO1 TfoX_C GST_N
Other DBs
NCBI-GeneID: 30298
NCBI-ProteinID: NP_571162
ZFIN: ZDB-GENE-980526-123
Ensembl: ENSDARG00000018882
UniProt: C0RW38
Position
5:66043820..66118416
AA seq 1126 aa
MDMETAVCEPHYQNGDVHHEDPCPKQPTVLKIHLYHSSRSDADSSPICYPPGEYITEQLI
IHAAKESGVSPVYCSLFGLYKEDEAVWLSPNHVLHLDETANESLLFRMRYYFPGWYSCGT
SRAYRYGVTKGSDSPVLDDYVMSYLFAQWRSDFVNGWVKLSGSHENQEECLGMAVLDMMR
TAKEKDCSPLDIYNDISYKSFLPKDMRERIQDYHFVTRKRIRYRFRKVVQQLSQCRVTAR
DLKLKYLISLESLDNGFYTERFQVKEPSTEQVTIVVSADRGIQWCHERHKDTQSEDLLQT
YCDFAEVVDISIRQASKDGTNMNRIVSIDRQDGTPLELVFSTSMQALSFVSLIDGYYRLT
TDAHHYLCKDVAPPYLLEAIESYCHGPISMDFAISKLRKSGNQKGLFVLRCSPKDYNKYF
LTLAFGGYGNVEYKHCLITRSESGNYNLSGTKKSFRSLQDLLKCYQKETVKSDGIVFQFS
KCCSPRPKEKSSLLVCRSHRGLEVPLSSSLQRHNISQMVFHKIKKEDLELGESQGQGTFT
KIFKGIRKEQGDYGETHKTEVIVKVLDKAHRNYSESFFEAASMMSQLTHKHLVLTYGICV
CGDENIMVQEYVKFGSLDTYLKKNKSSVSVNILWKLEVAKQLAWAMLYLEEKSLAHGNVC
AKNILLIREEDRALGNTPFIKLSDPGISITVLPREILVERIPWVPPECILDPKNLSLATD
KWSFGTTLWEICSGGEQPLANMDNSKKHLFYENHHQLPAPKWTELANLINSCMDYEPTFR
PSFKAIIRDLNSLFCPDYEIVKESDIMPSRAAASIFNTGTFKNNEPVQFEERHLIFLQQL
GKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTTEHIRDFEREIEILKSLQHENIVKYKG
VCYGAGRRNLRLVMEYLPYGSLRDYLNKNRDRIDHQKLVHYASQICKGMEYLATKRYIHR
DLATRNILVESECRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWHAPESLTESKFSVAS
DVWSFGVVLYELFTYSDKLCSPPTVFLSMVGGDKQGQTIVYHLIELLKRGNRLPQPMGCP
TEMFEIMQECWDNDPSLRPNFKELALRVDLIRDSSDADRYTQVPEF
NT seq 3381 nt   +upstreamnt  +downstreamnt
atggacatggagacagctgtctgtgagcctcattaccagaatggtgacgtccaccacgag
gatccttgtccaaagcagcccaccgttctcaagatccacctgtaccatagcagccggagc
gacgccgactccagcccgatctgttacccgcctggagagtacatcacagagcagctcatc
atccacgctgccaaggagagcggagtgtcaccagtatactgcagcctctttgggctctac
aaagaagatgaagccgtctggttatcacccaatcacgtcctccatttagatgaaaccgcc
aatgagagtttgctatttagaatgaggtactattttcctggctggtacagttgcgggacg
tcccgggcgtaccgctatggagtgactaagggatccgatagcccagtcctagacgactat
gtaatgtcttacctctttgctcagtggaggagtgactttgtcaatggctgggtgaagttg
tcgggaagccacgagaatcaggaggagtgccttggcatggctgtgttggacatgatgagg
actgccaaagagaaagattgctcgccgctggacatctataatgacattagttataaatca
ttcctcccgaaagacatgagggagcgaatccaggactatcattttgtcacaagaaagcgc
atccgctatcgcttccgaaaagtggtgcagcagctgagccagtgccgggtcacagcgcga
gacctaaagctcaaatacctgatcagcctggagtctctggacaatggtttctacaccgaa
cgcttccaggtcaaagagccttcgaccgagcaggtcactatcgtcgtctctgcagatcga
ggcattcagtggtgccacgagcgacataaagacacacagtctgaggacctgctgcagacg
tattgtgatttcgcggaagttgtcgatatcagtatcaggcaagccagcaaagacggtacc
aacatgaaccgcattgtctccatcgacagacaggatggaacacctctagagttggtgttt
tccacctcaatgcaggccttgtcttttgtatctctaattgatggttactacagactgacc
acagatgcccatcactacctctgtaaggatgtcgccccgccgtatctgctggaagccatc
gagagctactgccacggcccgatatcaatggattttgcgatcagtaaactacgcaagtca
gggaaccagaaaggcctctttgtgctccgatgcagccctaaagactacaacaaatacttt
ctgactcttgcattcggggggtatggaaatgtagagtacaagcactgtctcattaccaga
tctgaaagcggcaactacaatcttagtggaaccaaaaagagttttagaagcttacaggat
ctgctgaagtgttaccagaaggaaacagtgaaatctgatggtatcgtctttcagttcagc
aagtgctgttcaccaaggcccaaagagaagtcgagtttgctggtgtgcagaagtcatcgg
ggtttggaggttcctctgtcctcctcactgcagagacacaacatcagccagatggtcttt
cacaaaatcaagaaagaagacctcgagcttggtgaaagtcaaggtcagggaacttttaca
aagatcttcaaagggattcggaaagagcagggagactatggagaaacccataaaactgaa
gtcattgtcaaagtcttggacaaagcacacagaaattattctgagtctttcttcgaggcg
gccagcatgatgagtcagctcactcacaagcatctggtgttgacctacggcatctgtgtg
tgcggagacgagaacatcatggtgcaggaatatgtcaagtttggctccttggacacatat
ctgaagaaaaacaagagctcggtatcagtcaatatcctgtggaagctggaagtggccaag
cagctcgcctgggctatgctctatttggaggagaagagtctggctcatgggaacgtgtgc
gcaaaaaacatccttttgatcagggaggaggacagggcgctgggaaacacgccgttcatt
aaactgagtgaccctggcatcagcatcactgtgctgcccagagagattctcgtagagcga
atcccctgggtgccccctgaatgcatattagaccccaaaaacctgagtctagccactgac
aaatggagctttgggacaactttatgggagatttgcagcggaggagaacagccacttgcc
aacatggacaattccaagaaacacttattttatgaaaaccatcaccaactacccgccccg
aagtggacagagctggctaacctgatcaacagctgcatggactacgagccgacgttcagg
ccatcgttcaaagccatcattcgagacctaaacagtctcttctgccctgattatgagatc
gtgaaggagagcgacatcatgcccagcagagcagcagcgtctatattcaacactggaaca
tttaagaataatgaacccgtgcagtttgaggagagacatctgattttcctgcagcagctg
ggcaagggtaattttggcagtgtggaaatgtgcaggtacgaccctctgcaggacaacacc
ggcgaggtggtggcggtgaaaaagcttcagcacagcaccactgagcacattcgggacttt
gagcgggaaatcgagatccttaaatccctccagcatgagaacattgtgaaatataaaggc
gtgtgctacggtgcagggaggagaaacctacggctggttatggagtacctgccttacgga
agtctacgggactatctcaacaaaaacagagatcggattgaccaccagaaacttgtccat
tatgcatctcagatatgcaagggcatggaataccttgcgacgaaacggtacattcaccga
gacctggccacacgaaacatcctggtggagagcgagtgcagggtgaagattggagacttt
ggcttgaccaaggttttacctcaggacaaagagtactacaaggttaaggagcctggagag
agtcccattttctggcatgctcctgagtctctgactgagagcaagttctcggtagcgtcc
gacgtctggagtttcggagtggttctgtatgaactctttacatacagcgacaagctctgt
agcccaccgacggtgtttttgagtatggtcggaggcgacaagcagggacaaacgatagtc
tatcatctcatcgagctgttgaaaagaggaaaccgtttaccacaacccatgggctgtcct
acagagatgttcgagatcatgcaggaatgctgggacaacgatcctagtcttcggccaaat
ttcaaagagcttgctctccgcgtagacctgatccgggacagcagcgatgcagaccgatat
acccaagtgcctgagttttga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (26)   
   KEGG ORTHOLOGY (1)   
   RefGene (20)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   ZFIN (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (2)   
DNA sequence (8)   
   RefSeq(nuc) (2)   
   GenBank (3)   
   EMBL (3)   
Protein domain (11)   
   Pfam (11)   
All databases (57)   

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