KEGG   Danio rerio (zebrafish): 321070
Entry
321070            CDS       T01004                                 
Symbol
rock2b
Name
(RefSeq) rho-associated protein kinase 2b
  KO
K17388  Rho-associated protein kinase 2 [EC:2.7.11.1]
Organism
dre  Danio rerio (zebrafish)
Pathway
dre04270  Vascular smooth muscle contraction
dre04310  Wnt signaling pathway
dre04510  Focal adhesion
dre04520  Adherens junction
dre04530  Tight junction
dre04810  Regulation of actin cytoskeleton
dre05132  Salmonella infection
Brite
KEGG Orthology (KO) [BR:dre00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    321070 (rock2b)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    321070 (rock2b)
   04520 Adherens junction
    321070 (rock2b)
   04530 Tight junction
    321070 (rock2b)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    321070 (rock2b)
 09150 Organismal Systems
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    321070 (rock2b)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    321070 (rock2b)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:dre01001]
    321070 (rock2b)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:dre03036]
    321070 (rock2b)
Enzymes [BR:dre01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     321070 (rock2b)
Protein kinases [BR:dre01001]
 Serine/threonine kinases: AGC group
  DMPK family [OT]
   321070 (rock2b)
Chromosome and associated proteins [BR:dre03036]
 Eukaryotic type
  Centrosome formation proteins
   Kinases and associated factors
    321070 (rock2b)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Rho_Binding PH Pkinase_C C1_1 APH
Other DBs
NCBI-GeneID: 321070
NCBI-ProteinID: NP_001087216
ZFIN: ZDB-GENE-060125-2
Ensembl: ENSDARG00000004877
UniProt: A0A8M1NDD8
Position
20:complement(33575452..33705230)
AA seq 1401 aa
MSTGAGKRIESRVRKLETLIKNQKSPLNLESLLDSVTALALDLNHPALRKNKNIDAFLSR
YEKAVCNLKELQVKLDDFDRVKLIGRGAFGAVQLVRHKVSQQVYAMKQLSKFEMVKRSDS
AFFWEERDIMAFSQSPWIVQLCCAFQDEKYLYLVMEFMPGGDLVTLTSNYDIPEEWAQFY
TAEVVLALDAIHSLGFIHRDIKPDNMLLDRNGHLKLADFGTCMKMDSTGMVRCDTAVGTP
DYISPEVLMSQGGTGYYGRECDWWSVGVFIYELLVGDTPFYSESLVGTYGKIMDHKNSLT
FPDDIEMSKNAKDLICAFLSSREVRLGRTGVDEIKCHPFFKNDQWTFDTIRDTMAPVVPE
LSSDIDTSNFDDDIKDDPIGTETFPPPRAFAGNQLPFVGFTYFREDQLLTQQNKCSEEDI
IEDHGLNHTESNDLEKRLKKLEEKFKHEMQAKEELENKCRIANQRLEKLSKDLEEEVNAR
QEAEDNLRSLEKEKVLLKHQRTQSVRKAGLETDRKRLLENEVSSLKEQLAELKKKNQISH
LSAEKNIHLERQLEEVSAKLQAELEESERLKKAQIEAFRQSQQLELSLRELQERLAQLEN
SRLVLEQDKLSLQTSLELEKRERNAGSETITDLQGRIYGLEGELKHIKSSLSKAEVEKRQ
LQEDLTTLEKEKNKQEIDLSFKLKAVQQSLEQEEAEHKTTKARLADNNKINQSIEAKSET
LKDMEHKLLEERSAKQQLENRLMQLEKENSVLDCDYKQAKHELQELRSLKENLTEQVEVL
NVRVQQETQRKTLCQGDLKVQRQEINSLRSSEQQLKQELNHLLELKLTLEKQNQELSKER
EESEKQLKEMKDQLEAEQYFTKLYKTQIRELKEESDEKVKLYKDAQQRIEDLQEERDSLA
SQLEVSLTKADSEQLARITVEEQYSDLEKEKIMKELEIKDMIARHRQDLAEKDGTINSLE
ESNRTLTVDVANLASEKEELNNKLKHIQQKLEKIKEEEKQMKSLTVSYEKQIQVEKTLKI
QAINKLAEVMKKTDGRPHQINNTDIRRKEKEIRQLQLQLRTEKEKLNHSIIKYQREINDM
QAMIAEESQVRLEMQMSLDSKDSDIERLRSQLTSLSIHSLDTTSISSIGNDLDSDEAYPA
AESGLEGWLSMPAKNTKRFGWDKKYVVVSSKKILFYDSEQDREQSSPFMILDIDKLFHVR
PVTQTDVYRADPREIPRIFQILYANEGESKKEELPVESLSVTERSLCIPHKGHEFVLTLY
HFPSSCEVCPRPLWHVFRPPPALECRRCRVKCHKDHIDRKEEVLAPCRVNYDMSTAKEML
LLANSTEEQKKWVSRLLKRVPRKPSIAHSSSIAISAAPSEATPTTLSPQPSPRLAQSSPR
LSHRAAVKVHSTRQQPSSKNR
NT seq 4206 nt   +upstreamnt  +downstreamnt
atgtcgaccggagcggggaagagaatagagagccgggtgagaaaactagagacgctgatc
aagaaccagaaatcaccgttgaacttggagagtttgctggattcagtaactgcccttgcc
cttgatctgaaccatccagcactgagaaagaacaaaaacatagatgccttcttaagcaga
tatgaaaaagccgtgtgcaacctcaaggaactacaggtgaagctggatgattttgatcga
gtcaagctgatcggtcgtggagcgtttggcgcagtgcagctggtacggcacaaagtatct
caacaagtttatgccatgaagcagctcagcaagtttgagatggtcaagcgctctgactcc
gcctttttctgggaggagcgtgacatcatggctttctcccagagcccttggatagttcag
ctgtgctgtgcattccaagatgaaaagtacctttatttggtgatggagttcatgccaggt
ggagatctggtgactctgaccagcaactatgacatcccagaggaatgggctcaattctat
acggcagaagtggtgctggcactcgacgccatccattctctgggcttcatccacagagac
atcaaaccagacaacatgctgctggaccgcaatggacacctcaaactcgcagactttggc
acatgcatgaagatggactcgactggtatggtacgctgtgacactgctgttgggacacct
gattacatttctccagaggttttaatgtctcaaggagggactggttattacggtcgcgag
tgtgactggtggtctgttggtgtttttatttatgagcttctagtgggcgacactccattt
tattccgagtctctggtgggcacatatggaaagatcatggatcacaagaacagcttaact
ttcccagatgatattgaaatgtcaaagaatgccaaagacctcatctgtgcctttctgagt
agcagggaggtgaggcttggccgaactggagtggatgaaataaaatgtcaccccttcttt
aagaatgatcagtggaccttcgacaccatacgagacaccatggctccagtggtgccagag
ctgagtagcgatattgacaccagtaactttgatgatgacattaaggatgatccgatagga
acagagacgttccctccgccccgtgccttcgcagggaaccagctaccatttgtgggtttc
acctatttcagggaggaccaattgttaacacaacaaaataagtgttcagaggaagatatc
attgaagatcatggcttaaaccacacagagtctaacgacctggagaagaggctgaaaaag
ttggaggaaaaattcaaacatgagatgcaagcaaaggaagaactggaaaataaatgccga
atagcaaatcagcggctggagaaattgtccaaagatcttgaagaagaagtgaatgcgaga
caggaggcggaagacaacctgagatccctggagaaagagaaagttttactgaaacaccag
cgtacacagagcgtaagaaaagctggtctagagaccgacagaaaacggctgctggagaat
gaagtaagcagcctgaaagagcagcttgccgaactgaagaaaaagaaccagatctctcat
ctgtctgctgagaagaacattcacctggaaagacagctggaggaggtgagtgccaagctt
caggccgagctggaggagtcggagaggctgaagaaggcccagatcgaggcctttagacag
tcccagcagctggagctttccctcagggagctgcaggagcgtctggcccagctggagaac
agcaggctggttctggagcaggacaaactcagcctgcagacctcgctagagctggagaaa
cgagagagaaacgccggctcagagaccatcactgacctgcagggtcgtatctatggactg
gagggtgagttgaagcatataaagagttctctatcaaaagctgaagttgagaaaagacaa
ttacaagaggatcttacaaccctggaaaaggagaagaataagcaggagatcgacctctcc
ttcaaactcaaagcagttcagcagagtctggagcaggaggaggctgaacataaaaccact
aaagccagattggccgacaacaacaaaatcaaccaatccatagaggcaaagtctgagacc
ctgaaagacatggaacataagctgttggaagaacgatctgcgaagcaacaactggaaaac
agactgatgcagctggagaaggaaaactctgtattagactgtgattacaaacaagccaaa
catgagcttcaggagctccgctcgctcaaagaaaatctcacagagcaggtggaggtgctg
aatgtgcgggtgcagcaggagacacagaggaaaactctctgtcaaggtgatctcaaagtt
cagaggcaggagatcaacagcctgcggtcatcagaacaacagctcaaacaagaactcaac
catctgctggagctcaaactcacactggagaaacaaaaccaggagctgtccaaggaacga
gaagaatctgaaaaacagctgaaggagatgaaggaccagctggaggctgagcagtacttc
acgaaactgtacaagactcagattcgagagctgaaagaggaaagcgatgaaaaggttaaa
ctctacaaagatgctcagcagagaatagaggacctgcaggaagagagggactcgttagcg
tctcagttggaggtgagcctgacgaaggctgactctgaacagttggctcgcatcaccgtt
gaagagcaatactcggacctggagaaagagaagatcatgaaggaactggagataaaggac
atgatcgccagacaccggcaggatcttgcagaaaaggacggtaccatcaactcgctggag
gagtcaaaccgtacgctgactgtggatgttgccaacctggccagtgagaaagaggagctc
aacaataaactgaagcacatacagcaaaagctggagaagatcaaagaagaagagaaacag
atgaaatctctcacagtgtcgtatgagaagcagatacaggtggagaaaacactcaagatt
caggctataaacaagctggcggaggtcatgaagaagacggacggcaggccacaccaaatc
aacaacacagacatccgcaggaaggagaaggagatcagacaactccagctgcagctccgc
acggagaaagaaaagcttaaccactccatcatcaaataccagagagaaatcaacgacatg
caggctatgatagcagaggagtctcaggtgcgtctggagatgcagatgtctctggacagt
aaagacagtgatattgagcgtctgcgcagtcaactcacgtctctgagcattcactctctg
gacaccaccagcatcagcagcatcggcaatgacctggattctgacgaggcatatccagcc
gcagagtccggtcttgaaggatggctctcaatgcctgccaaaaacaccaaacggtttgga
tgggataagaagtatgtggtcgtgagcagcaagaagatcctgttttatgactctgaacaa
gaccgagagcagtccagtccattcatgatcctggacattgacaaactcttccacgtgaga
cccgtcactcagacagatgtttaccgcgcagatcccagagaaatccctcgcatcttccag
atactatatgcgaatgaaggagagagcaagaaagaggagctgcccgtggagtcgttatct
gtgactgagaggtcactgtgtatcccacacaagggtcacgagtttgttctgacgctttat
cacttcccctcgagctgcgaggtctgtccacgacccctatggcacgtcttcagacctccg
ccggctctcgagtgcagacgctgtagagtcaagtgccataaagaccacatcgatcgcaaa
gaagaggtcctcgctccatgtagagtgaattacgacatgtccacagcgaaagagatgctg
ctgctggcaaactccacagaggagcagaagaagtgggtcagtcggctgctcaagagggtt
ccgcgtaaaccctccatcgcccactcttccagcatagccatatccgctgcgccctcagag
gcaacacccactaccctttcccctcagccgtcgcctcgcctcgctcagtcttcacccaga
ctttcacaccgagcagccgtcaaagtgcactctacacgacagcagccctccagcaagaac
aggtga

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (7)   
   KEGG PATHWAY (7)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (79)   
   KEGG ORTHOLOGY (1)   
   RefGene (73)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   ZFIN (1)   
Protein sequence (13)   
   UniProt (1)   
   RefSeq(pep) (12)   
DNA sequence (14)   
   RefSeq(nuc) (12)   
   GenBank (1)   
   EMBL (1)   
Protein domain (7)   
   Pfam (7)   
All databases (126)   

Download RDF
DBGET integrated database retrieval system