KEGG   Danio rerio (zebrafish): 560486
Entry
560486            CDS       T01004                                 
Symbol
xdh
Name
(RefSeq) xanthine dehydrogenase/oxidase
  KO
K00106  xanthine dehydrogenase/oxidase [EC:1.17.1.4 1.17.3.2]
Organism
dre  Danio rerio (zebrafish)
Pathway
dre00230  Purine metabolism
dre00232  Caffeine metabolism
dre00983  Drug metabolism - other enzymes
dre01100  Metabolic pathways
dre01232  Nucleotide metabolism
dre04146  Peroxisome
Module
dre_M00546  Purine degradation, xanthine => urea
dre_M00958  Adenine ribonucleotide degradation, AMP => Urate
dre_M00959  Guanine ribonucleotide degradation, GMP => Urate
Brite
KEGG Orthology (KO) [BR:dre00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    560486 (xdh)
  09110 Biosynthesis of other secondary metabolites
   00232 Caffeine metabolism
    560486 (xdh)
  09111 Xenobiotics biodegradation and metabolism
   00983 Drug metabolism - other enzymes
    560486 (xdh)
 09140 Cellular Processes
  09141 Transport and catabolism
   04146 Peroxisome
    560486 (xdh)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:dre04147]
    560486 (xdh)
Enzymes [BR:dre01000]
 1. Oxidoreductases
  1.17  Acting on CH or CH2 groups
   1.17.1  With NAD+ or NADP+ as acceptor
    1.17.1.4  xanthine dehydrogenase
     560486 (xdh)
   1.17.3  With oxygen as acceptor
    1.17.3.2  xanthine oxidase
     560486 (xdh)
Exosome [BR:dre04147]
 Exosomal proteins
  Exosomal proteins of breast milk
   560486 (xdh)
SSDB
Motif
Pfam: MoCoBD_2 MoCoBD_1 FAD_binding_5 Ald_Xan_dh_C CO_deh_flav_C Fer2_2 Fer2
Other DBs
NCBI-GeneID: 560486
NCBI-ProteinID: XP_688983
ZFIN: ZDB-GENE-070719-9
Ensembl: ENSDARG00000055240
UniProt: E7F022
Position
17:33340825..33374290
AA seq 1351 aa
MSISEDKIKNKLQSPGDDLVFFVNGKKITEKNADPEITLLTYLRRSLGLTGTKLGCAEGG
CGACTVMVSKYHPNQNRIIHYAINACLAPLCSLHHCAVTTVEGIGSVASKLHPVQERIAK
AHGSQCGFCTPGIVMSMYALLRNNPQPTMHDIQEAFQGNLCRCTGYRPILEGYRTFTKDG
GCCGGKSQTNGCCMTNGNTQEHENSAHPVQHLYDQSEFMPLDPTQEIIFPPELVSLSKQT
QREMRFVGERVLWIQPCSLKELLELKATYPNAKLVVGNTEVGIEMKFKNLLYPVILAPAY
IPELNIIQHTQDGIEVGASVTLTVLGDVLQSAVKKLPAYQTEVFKAVLEQLRWFAGQQIR
NVAAVGGNIMTASPISDLNPVFMAAGCKLTVMSKGEKRVLEMDDKFFTGYRKTALKPEEI
LLSIEIPYTKKGQYFSAFKQSPRKEDDISIVTCGMNVYFKEQSNTVQSIRISYGGMAPVT
VLATATCNKLLNRQWNEDLLEEACSSLAEEMSLSPSAPGGMVTYRRTLTISLFYKFFLTV
QHKLAVSLQMEGVTVEDIQPEFSTATELFQVDTPSSVQLYQEVPPGQNEDDVVGHPIIHL
SALKQATGEAVYCDDMPCYENELHLALVTSTKAHALIKSIDTSSAMSVPGVVAFISAKDI
PGSNMTGPVVYDETVFADDKVTCVGHIVGAIVADTQAHAQRAAKVVKISYEELKPVIVTI
QDAINNKSFFEPVRTIEKGDVAQGFKDSDHILHGEMHIGGQEQFYLETNCTLAVPRGEDG
EMELFVSTQSASKTQALVAKALGVPANRVVCRVKRMGGGFGGKESRSTILSTVVAVAAQK
VKCPVRCMLDRDEDMLVTGGRHPFFGQYKVGFMKNGRVMALEVTLYSNAGNSLDLSLSIL
ERALFHMDNSYNIPNICGTGYMCKTNLPSNSAFRGFGGPQGMMIAESWMSDVALSCGLPA
EEVRRMNMYNEGDLTHFNQRLDQFTIARCWEECMQLSDFNKRKDAVEKYNRQHRWTKRGL
SIIPTKFGISFTAVFLNQAGALVHVYSDGSVLLTHGGTEMGQGLHTKMVQVASKTLEIPC
TKIHITETSTSTVPNTSPTAASASSDLNGMAVYNACQTILQRLQPFKEKNPKGCWEDWVT
AAYFDRVNLSANGFYKTPDLGYDFDTNSGRPFNYFSYGVAVSEVEIDCLTGSHKNLHTSI
VMDVGKSLNPALDIGQVEGGFMQGLGLFTLEELRYSPDGYLYTRGPGMYKIPAFGDIPSE
LKVSLLRDAPNDKAIFSSKAVGEPPLFLAASVFYAIKDAITAARAESGLTGPFRLDSPAT
PERIRNACEDKFTKLCPPADPGTFIPWAVQV
NT seq 4056 nt   +upstreamnt  +downstreamnt
atgtccatcagcgaggataagattaaaaacaaacttcagtctccaggggatgaccttgtc
ttcttcgttaatggaaaaaagatcactgagaagaatgcagaccctgaaataacactcttg
acttatcttagaagaagcttgggtctgacaggaaccaaactgggatgtgctgaaggaggt
tgtggagcctgcactgtaatggtctccaaatatcatccaaatcaaaaccggattattcac
tatgccattaatgcctgtctggctcctctgtgctctttgcatcactgtgcggtaacaacc
gtggagggcatcggcagcgtggcaagcaaactccatcccgtacaggagcgaattgcaaag
gctcacggctcacagtgtgggttctgtactccaggaattgtgatgtctatgtacgctctt
ttaagaaacaacccacaacccaccatgcatgacattcaggaggcttttcaaggaaactta
tgccgctgtactggttacagacctattctagaaggctacaggacattcacaaaggatggg
ggatgttgtggtgggaaaagtcagactaatggctgctgtatgactaatggaaacacacaa
gagcatgaaaattcagcacatccagttcagcacttgtatgaccaatcagagtttatgcca
ctggacccgacacaagagattatttttccacctgagcttgtgagtctgagtaaacagacc
caaagagagatgaggttcgttggggagcgagtgctttggattcaaccctgctccctcaag
gagcttctggagctgaaggccacatatccaaatgccaaactagtcgttgggaacacagaa
gttggcattgagatgaaattcaaaaaccttctttatcctgtgattctggcaccagcttac
attccagaactgaatatcatccaacacactcaggatggtattgaggttggcgcatcagtg
acgttgactgtgctgggggatgtcctgcagtcagctgtgaagaagttgcccgcttatcaa
actgaggtttttaaggctgttctagagcagctgcgctggtttgcaggacagcagatccga
aatgttgcagctgttggtggaaatattatgacggcaagtcccatttcagacctcaaccct
gtgtttatggcagctggctgcaagctaacagtgatgtccaaaggggagaaacgagttctt
gaaatggatgacaagttcttcactggttatcgtaagactgctttgaagccagaggagatt
cttttgtccattgagattccatacacaaaaaagggccagtacttctcagccttcaagcaa
tcccctcgcaaagaggatgatatctctattgtcacgtgtgggatgaatgtatatttcaag
gagcaatccaatacagtacagagtatccgaataagctatggaggaatggcccctgtcact
gttcttgctacggccacatgcaacaagttgcttaacaggcaatggaatgaagatcttctt
gaggaagcctgcagctcattggctgaggagatgagtctatctccctcagctccgggtggg
atggtgacatacaggcgcacattgactatcagcctcttctacaaattcttcctcactgtc
cagcacaaactggctgtgagcctgcagatggagggtgttaccgttgaagacatccaacct
gagttttccactgctactgaactcttccaagtggacacaccatccagtgtacagctttat
caggaagttcctccaggtcaaaatgaggatgatgttgtggggcaccctatcatacacctc
tctgctcttaaacaggccacaggagaagcggtatactgtgacgacatgccttgctatgaa
aatgagcttcatttggctttagtcaccagcactaaagctcatgccctcataaaatccatt
gacacctccagtgcgatgtcagttcctggagtggttgcatttatttctgccaaagacatc
cctggaagtaatatgactggacctgttgtctatgatgagacagtttttgcagatgataag
gtcacatgcgttggacatatagtgggggccattgtggcagacactcaggctcatgcgcag
agagcagccaaagtggtgaagatcagctatgaggaactgaagcctgtcattgtgaccatt
caggatgctattaacaacaagtcattcttcgagccagttagaactatagaaaaaggagat
gttgcacaaggatttaaagactctgatcacatcctgcacggtgagatgcacattggaggg
caggaacagttttatctggagactaactgcacgctggctgtccctcgtggagaggatgga
gaaatggagctgtttgtgtccacacagtcggcctccaagacacaagctctggtggctaaa
gctttaggtgttcctgctaatcgggtggtgtgtcgtgtgaagagaatgggtggaggattt
ggagggaaagagagtcggagcaccattctatccactgtggttgctgttgccgcacaaaag
gttaagtgcccggttcgctgcatgttagatcgtgatgaggacatgctggtcacaggtggc
cgccatcctttctttggacagtacaaggtgggttttatgaagaatggaagagtgatggca
cttgaggtgacgctctacagcaatgcaggcaattcactggacctgtcattgtcaatcctg
gagagggcgctgttccacatggataactcctacaacattcctaacatttgtggcacaggc
tacatgtgtaaaaccaacctgccgtctaattctgcattcagaggctttggtgggccgcag
ggcatgatgatcgcagagagctggatgagtgatgtggccttgagctgcggtctgcctgcc
gaagaggtgaggaggatgaacatgtataatgagggagatctcacacactttaatcaacgt
ctggaccagttcaccatcgctcgctgctgggaggagtgcatgcagctctcagacttcaac
aagcgcaaggatgctgtggagaaatacaacaggcagcaccgctggaccaagagagggctg
tccatcattcccaccaaatttggcatcagctttactgctgttttcctcaaccaggcaggg
gcattggtacatgtgtactcagatgggtctgtactgctaactcatggtggaacagaaatg
gggcaaggtctgcacacaaaaatggtccaggtggctagtaaaacacttgaaatcccctgc
acaaagattcacattacagagaccagcactagcacagttcccaacaccagccctacggcc
gcatccgcctcctctgacctcaacgggatggccgtctataatgcttgccagactatacta
cagagacttcagccttttaaagaaaagaaccccaaaggctgctgggaagactgggtcaca
gcagcctactttgacagagtaaatctgtctgccaatggattctacaagactccagatctt
ggttatgattttgacaccaactcaggaaggccttttaactacttcagttatggtgtggcc
gtctcagaagtggagatagactgtctaactggcagtcataagaatcttcatacgtccata
gtgatggatgtgggcaagagtttaaatccagcactggacattggacaggtagaaggtggg
ttcatgcaaggcttaggtctgttcacgctagaggaacttcgctactctcctgacggttac
ctatatactcgtggacctggcatgtataagattcctgcttttggggatattcccagtgaa
ttaaaggtttcgctgctcagagatgctccaaatgacaaagccatcttttcttcaaaggct
gtgggtgaacctcctctctttctggcggcctcagtgttttatgccattaaagatgccatc
acagctgccagggctgagtctggactgaccggacccttcagattggacagccctgccact
cctgaacgcatacgaaatgcctgtgaagataagtttaccaaattgtgtcctcctgcggat
cctggcacctttattccatgggcagtgcaggtctga

  All links  
Gene (34)   
   RefGene (29)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   ZFIN (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (7)   
   RefSeq(nuc) (1)   
   GenBank (3)   
   EMBL (3)   
Protein domain (7)   
   Pfam (7)   
All databases (50)   

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