KEGG   Desmodus rotundus (common vampire bat): 112298645
Entry
112298645         CDS       T05907                                 

Gene name
GRB2
Definition
(RefSeq) growth factor receptor-bound protein 2
  KO
K04364  growth factor receptor-binding protein 2
Organism
dro  Desmodus rotundus (common vampire bat)
Pathway
dro01521  EGFR tyrosine kinase inhibitor resistance
dro01522  Endocrine resistance
dro04010  MAPK signaling pathway
dro04012  ErbB signaling pathway
dro04014  Ras signaling pathway
dro04062  Chemokine signaling pathway
dro04068  FoxO signaling pathway
dro04072  Phospholipase D signaling pathway
dro04150  mTOR signaling pathway
dro04151  PI3K-Akt signaling pathway
dro04380  Osteoclast differentiation
dro04510  Focal adhesion
dro04540  Gap junction
dro04550  Signaling pathways regulating pluripotency of stem cells
dro04630  JAK-STAT signaling pathway
dro04650  Natural killer cell mediated cytotoxicity
dro04660  T cell receptor signaling pathway
dro04662  B cell receptor signaling pathway
dro04664  Fc epsilon RI signaling pathway
dro04714  Thermogenesis
dro04722  Neurotrophin signaling pathway
dro04910  Insulin signaling pathway
dro04912  GnRH signaling pathway
dro04915  Estrogen signaling pathway
dro04917  Prolactin signaling pathway
dro04926  Relaxin signaling pathway
dro04935  Growth hormone synthesis, secretion and action
dro05034  Alcoholism
dro05160  Hepatitis C
dro05161  Hepatitis B
dro05163  Human cytomegalovirus infection
dro05165  Human papillomavirus infection
dro05200  Pathways in cancer
dro05203  Viral carcinogenesis
dro05205  Proteoglycans in cancer
dro05206  MicroRNAs in cancer
dro05210  Colorectal cancer
dro05211  Renal cell carcinoma
dro05213  Endometrial cancer
dro05214  Glioma
dro05215  Prostate cancer
dro05220  Chronic myeloid leukemia
dro05221  Acute myeloid leukemia
dro05223  Non-small cell lung cancer
dro05224  Breast cancer
dro05225  Hepatocellular carcinoma
dro05226  Gastric cancer
dro05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:dro00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    112298645 (GRB2)
   04012 ErbB signaling pathway
    112298645 (GRB2)
   04014 Ras signaling pathway
    112298645 (GRB2)
   04630 JAK-STAT signaling pathway
    112298645 (GRB2)
   04068 FoxO signaling pathway
    112298645 (GRB2)
   04072 Phospholipase D signaling pathway
    112298645 (GRB2)
   04151 PI3K-Akt signaling pathway
    112298645 (GRB2)
   04150 mTOR signaling pathway
    112298645 (GRB2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    112298645 (GRB2)
   04540 Gap junction
    112298645 (GRB2)
   04550 Signaling pathways regulating pluripotency of stem cells
    112298645 (GRB2)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    112298645 (GRB2)
   04660 T cell receptor signaling pathway
    112298645 (GRB2)
   04662 B cell receptor signaling pathway
    112298645 (GRB2)
   04664 Fc epsilon RI signaling pathway
    112298645 (GRB2)
   04062 Chemokine signaling pathway
    112298645 (GRB2)
  09152 Endocrine system
   04910 Insulin signaling pathway
    112298645 (GRB2)
   04912 GnRH signaling pathway
    112298645 (GRB2)
   04915 Estrogen signaling pathway
    112298645 (GRB2)
   04917 Prolactin signaling pathway
    112298645 (GRB2)
   04926 Relaxin signaling pathway
    112298645 (GRB2)
   04935 Growth hormone synthesis, secretion and action
    112298645 (GRB2)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    112298645 (GRB2)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    112298645 (GRB2)
  09159 Environmental adaptation
   04714 Thermogenesis
    112298645 (GRB2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    112298645 (GRB2)
   05206 MicroRNAs in cancer
    112298645 (GRB2)
   05205 Proteoglycans in cancer
    112298645 (GRB2)
   05203 Viral carcinogenesis
    112298645 (GRB2)
   05231 Choline metabolism in cancer
    112298645 (GRB2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    112298645 (GRB2)
   05225 Hepatocellular carcinoma
    112298645 (GRB2)
   05226 Gastric cancer
    112298645 (GRB2)
   05214 Glioma
    112298645 (GRB2)
   05221 Acute myeloid leukemia
    112298645 (GRB2)
   05220 Chronic myeloid leukemia
    112298645 (GRB2)
   05211 Renal cell carcinoma
    112298645 (GRB2)
   05215 Prostate cancer
    112298645 (GRB2)
   05213 Endometrial cancer
    112298645 (GRB2)
   05224 Breast cancer
    112298645 (GRB2)
   05223 Non-small cell lung cancer
    112298645 (GRB2)
  09165 Substance dependence
   05034 Alcoholism
    112298645 (GRB2)
  09172 Infectious disease: viral
   05161 Hepatitis B
    112298645 (GRB2)
   05160 Hepatitis C
    112298645 (GRB2)
   05163 Human cytomegalovirus infection
    112298645 (GRB2)
   05165 Human papillomavirus infection
    112298645 (GRB2)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    112298645 (GRB2)
   01522 Endocrine resistance
    112298645 (GRB2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:dro04131]
    112298645 (GRB2)
Membrane trafficking [BR:dro04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Receptor tyrosine kinase (RTK) adaptor proteins
    112298645 (GRB2)
SSDB
Motif
Pfam: SH3_1 SH3_9 SH3_2 SH2 SH3_10 SH2_2 SH3_3 DUF5093 hSH3 SH3_4
Other DBs
NCBI-GeneID: 112298645
NCBI-ProteinID: XP_024409427
Position
Unknown
AA seq 217 aa
MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPW
FFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFL
WVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRG
DFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV
NT seq 654 nt   +upstreamnt  +downstreamnt
atggaagccatcgccaaatatgacttcaaagccactgcagacgacgagctgagcttcaaa
aggggggacatcctcaaggttttgaatgaagaatgtgatcagaactggtacaaggcagaa
ctcaatgggaaagacggcttcattcccaagaattacatagaaatgaaaccacatccgtgg
ttttttggcaaaatccccagagccaaggcagaagaaatgctcagcaaacagcggcatgac
ggggccttcctcatccgagagagtgagagcgctcctggggatttctccctctcagtcaag
tttggaaatgacgtgcagcacttcaaggtgctccgagacggagccggaaagtatttcctc
tgggtggtgaagttcaattctttgaatgagcttgtagattatcacaggtctacatccgtc
tccagaaaccagcagatatttctccgggacatagaacaggtgccacagcaaccaacgtac
gtccaggccctctttgactttgacccccaggaggatggagagctggggttccgtcgggga
gactttatccacgtcatggataactcagaccccaactggtggaaaggggcttgccacggg
cagaccggcatgttcccccgcaattacgtcacccctgtgaaccggaacgtctaa

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