KEGG   Desmodus rotundus (common vampire bat): 112301160
Entry
112301160         CDS       T05907                                 
Symbol
CACNA1D
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1D isoform X1
  KO
K04851  voltage-dependent calcium channel L type alpha-1D
Organism
dro  Desmodus rotundus (common vampire bat)
Pathway
dro04010  MAPK signaling pathway
dro04020  Calcium signaling pathway
dro04022  cGMP-PKG signaling pathway
dro04024  cAMP signaling pathway
dro04218  Cellular senescence
dro04260  Cardiac muscle contraction
dro04261  Adrenergic signaling in cardiomyocytes
dro04270  Vascular smooth muscle contraction
dro04530  Tight junction
dro04713  Circadian entrainment
dro04723  Retrograde endocannabinoid signaling
dro04724  Glutamatergic synapse
dro04725  Cholinergic synapse
dro04726  Serotonergic synapse
dro04727  GABAergic synapse
dro04728  Dopaminergic synapse
dro04911  Insulin secretion
dro04912  GnRH signaling pathway
dro04921  Oxytocin signaling pathway
dro04924  Renin secretion
dro04925  Aldosterone synthesis and secretion
dro04927  Cortisol synthesis and secretion
dro04929  GnRH secretion
dro04930  Type II diabetes mellitus
dro04934  Cushing syndrome
dro04935  Growth hormone synthesis, secretion and action
dro04973  Carbohydrate digestion and absorption
dro05010  Alzheimer disease
dro05020  Prion disease
dro05022  Pathways of neurodegeneration - multiple diseases
dro05031  Amphetamine addiction
dro05207  Chemical carcinogenesis - receptor activation
dro05410  Hypertrophic cardiomyopathy
dro05412  Arrhythmogenic right ventricular cardiomyopathy
dro05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:dro00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    112301160 (CACNA1D)
   04020 Calcium signaling pathway
    112301160 (CACNA1D)
   04024 cAMP signaling pathway
    112301160 (CACNA1D)
   04022 cGMP-PKG signaling pathway
    112301160 (CACNA1D)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    112301160 (CACNA1D)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    112301160 (CACNA1D)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    112301160 (CACNA1D)
   04929 GnRH secretion
    112301160 (CACNA1D)
   04912 GnRH signaling pathway
    112301160 (CACNA1D)
   04921 Oxytocin signaling pathway
    112301160 (CACNA1D)
   04935 Growth hormone synthesis, secretion and action
    112301160 (CACNA1D)
   04924 Renin secretion
    112301160 (CACNA1D)
   04925 Aldosterone synthesis and secretion
    112301160 (CACNA1D)
   04927 Cortisol synthesis and secretion
    112301160 (CACNA1D)
  09153 Circulatory system
   04260 Cardiac muscle contraction
    112301160 (CACNA1D)
   04261 Adrenergic signaling in cardiomyocytes
    112301160 (CACNA1D)
   04270 Vascular smooth muscle contraction
    112301160 (CACNA1D)
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    112301160 (CACNA1D)
  09156 Nervous system
   04724 Glutamatergic synapse
    112301160 (CACNA1D)
   04727 GABAergic synapse
    112301160 (CACNA1D)
   04725 Cholinergic synapse
    112301160 (CACNA1D)
   04728 Dopaminergic synapse
    112301160 (CACNA1D)
   04726 Serotonergic synapse
    112301160 (CACNA1D)
   04723 Retrograde endocannabinoid signaling
    112301160 (CACNA1D)
  09159 Environmental adaptation
   04713 Circadian entrainment
    112301160 (CACNA1D)
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    112301160 (CACNA1D)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    112301160 (CACNA1D)
   05020 Prion disease
    112301160 (CACNA1D)
   05022 Pathways of neurodegeneration - multiple diseases
    112301160 (CACNA1D)
  09165 Substance dependence
   05031 Amphetamine addiction
    112301160 (CACNA1D)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    112301160 (CACNA1D)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    112301160 (CACNA1D)
   05414 Dilated cardiomyopathy
    112301160 (CACNA1D)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    112301160 (CACNA1D)
   04934 Cushing syndrome
    112301160 (CACNA1D)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:dro04040]
    112301160 (CACNA1D)
Ion channels [BR:dro04040]
 Voltage-gated cation channels
  Calcium channel, voltage-gated (Cav)
   112301160 (CACNA1D)
SSDB
Motif
Pfam: Ion_trans CAC1F_C Ca_chan_IQ GPHH PKD_channel
Other DBs
NCBI-GeneID: 112301160
NCBI-ProteinID: XP_024412280
Position
Unknown
AA seq 2181 aa
MMMMMMMKKMQHQRQQQADHANEANYARGTRLSLSGEGPTSQPNSSKQTVLSWQAAIDAA
RQAKAAQTMSTSAPPPVGSLSQRKRQQYSKSKKQGNSSNSRPARALFCLSLNNPIRRACI
SIVEWKPFDIFILLAIFANCVALAIYIPFPEDDSNSTNHNLEKVEYAFLIIFTVETFLKI
IAYGLLLHPNAYVRNGWNLLDFVIVIVGLFSVILEQLTKETEGGNHSGGKSGGFDVKALR
AFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHKT
CFFADSDIIAEEDPAPCAFSGNGRQCTANGTECRSGWVGPNGGITNFDNFAFAMLTVFQC
ITMEGWTDVLYWVNDAIGWEWPWVYFVSLIILGSFFVLNLVLGVLSGEFSKEREKAKARG
DFQKLREKQQLEEDLKGYLDWITQAEDIDPENEEEGGEESKRNTSMPTSETESVNTENVS
GEGENQGCCGSLWCWWKRRGAAEAGPSGCRRWGQAISKSKLSRRWRRWNRFSRRRCRAAV
KSVTFYWLVIVLVFLNTLTISSEHYNQPDWLTQIQDIANKVLLALFTCEMLVKMYSLGLQ
AYFVSLFNRFDCFVVCGGITETILVELEIMSPLGISVFRCVRLLRIFKVTRHWTSLSNLV
ASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQTKRSTFDNFPQALLTVFQ
ILTGEDWNAVMYDGIMAYGGPSSSGMIVCIYFIILFICGNYILLNVFLAIAVDNLADAES
LNTAQKEEAEEKERKKIARKESLENKKNNKPEVNQIANSDNKVTIDDYREEDEDKDPYPP
CDVPVDEEEEEEEEEDEPEVPAGPRPRRISELNMKEKIIPIPEGSAFFILSKTNPIRVGC
HKLINHHIFTNLILVFIMLSSASLAAEDPIRSHSFRNIILGYFDYVFTAIFTIEILLKMT
TFGAFLHKGAFCRNYFNLLDMLVVGVSLVSFGIQSSAISVVKILRVLRVLRPLRAINRAK
GLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYRCTDEAKSNPEECRGLF
ILYKDEDVDNPVVRERIWQNSDFNFDNVLSAMMALFTVSTFEGWPELLYKAIDSNGENVG
PIYNYRVEISIFFIIYIIIVAFFMMNIFVGFVIVTFQEQGEKEYKNCELDKNQRQCVEYA
LKARPLRRYIPKNPYQYKFWYVVNSSPFEYVMFVLIMLNTLCLAMQHYEQSKMFNDAMDI
LNMVFTGVFTVEMVLKVIAFKPKGYFSDAWNTFDSLIVIGSIIDVALSEADPNESENVPV
PTATPGNSEESNRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAM
LFFIYAVIGMQMFGKVAMRDNNQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACLPGK
LCDPESDYNPGEEYSCGSNFAIVYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGP
HHLDEFKRIWSEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVAMNMPLN
SDGTVMFNATLFALVRTALKIKTEGNLEQANEELRAVIKKIWKKTSMKLLDQVVPPAGDD
EVTVGKFYATFLIQDYFRKFKKRKEQGLVGKYPAKNTTIALQAGLRTLHDIGPEIRRAIS
CDLQDDEPEETKGEEEDVFKRNGALLGNHVNHVNSDRRDSLQQTNTTHRPLHVQRPSVPP
ASDTEKPLFPPAGNSVCHNHHNHNSIGKQVPSSTNANLNNANMSKAAPGKRPSIGNLEHV
SENEHESSHKLDHEPQRRSSIKRTRYYETYIRSDSGDEQFPTICREDPDIHSYFREPHCL
GEPEYFSGEEDYEDDSSPTSSRHNYSYYNRYPGSNLDFERPRGYHHPQGFLEDDDSPICY
DSRRSPRRRLLPPTPTSHRRSSFNFECLRRQSSQEEVPVSPAFPHRTALPLHLMQQQVMA
VAGLDSSKAQKYSPSHSTRSWATPPATPPYRDWTPCYTPLIQVEQSEALDQVNGSLPSLH
RSSWYTDEPGISYRTFTPASLTVPSSFHNKNSDKQRSADSLVEAVLISEGLGRYARDPKF
VSATKHEIADACDLTIDEMESAASNLLNGTMHPRANGDLGPVSSRQDYELQDFGPGYSDE
EPDLGREEEDLADEMICITTL
NT seq 6546 nt   +upstreamnt  +downstreamnt
atgatgatgatgatgatgatgaaaaaaatgcagcatcaacggcagcagcaagcggaccac
gcgaacgaggcaaactatgcaagaggcaccaggctttctctttctggggaaggaccaact
tctcagccgaatagctccaagcaaaccgtcctatcttggcaagccgcaatcgatgctgct
agacaggccaaggccgcccaaactatgagcacctccgcgcccccacctgtaggatctctc
tcccaaagaaaacgtcagcaatattccaagagcaaaaaacagggtaactcgtccaacagc
cgacctgcccgcgcccttttctgtttatcactcaataaccccattcgaagagcctgcatt
agtatagtggaatggaaaccatttgacatatttatattattggctatttttgccaattgt
gtggccttagctatttacatcccattccctgaagatgattctaattcaacaaatcataac
ttggaaaaagtagaatatgccttcctgattatttttacagtcgagacatttttgaagatt
atagcgtatggattattgctacatcctaatgcttatgttaggaatggatggaatttactg
gattttgttatagtaatagtaggattgtttagtgtaattttggaacaattaaccaaagaa
acggaaggcggtaaccactctggtggcaagtcaggaggctttgacgtcaaagccctccgc
gcctttcgagtgttgcggccacttcgactagtctcgggagtgcccagtttacaagttgtc
ctgaactccattataaaagccatggttcccctccttcacatagcccttttggtattattt
gtaatcataatctatgctattataggattggaactttttattggaaaaatgcacaaaacg
tgtttttttgctgactcagatatcatagctgaagaggacccggcgccgtgtgcgttctca
gggaatggacgccagtgtactgccaatggcacagagtgtaggagtggctgggttggccca
aacggaggcatcaccaactttgataactttgcctttgctatgctcactgtgtttcagtgc
atcactatggagggctggacagacgtgctctactgggtaaatgatgcgataggatgggaa
tggccatgggtgtattttgttagtctgataatccttggctcatttttcgtccttaacctg
gttcttggtgtccttagtggagaattctcaaaggaaagggagaaggcaaaagcccgggga
gatttccagaagctccgggagaagcagcagctcgaagaggatctaaagggctacttggat
tggattacccaagcagaagatattgatcctgagaatgaggaggaaggaggagaggaaagc
aaacgaaatactagcatgccaaccagcgagacggaatccgtgaacacagagaacgtaagt
ggtgaaggcgagaatcaaggctgctgtggaagtctctggtgctggtggaaaagaagaggc
gcggccgaggctgggccctctgggtgtcggcggtggggtcaagccatctcaaaatctaag
ctcagccgacgctggcgtcgctggaaccgattcagtcgcagaagatgtagggctgctgtg
aagtctgtcacgttctactggctggttattgtcctggtgtttctcaacaccctaaccatt
tcctctgagcactacaaccaacccgactggctgacacagattcaagatatcgcgaacaaa
gtcctcctggctctgttcacctgtgagatgctggtaaagatgtacagcttgggtctccag
gcatatttcgtctctctctttaatcggtttgattgtttcgtggtgtgtggaggaattacg
gaaacgatcttggtggaactggaaatcatgtctcccctggggatctctgtgtttcgctgt
gtgcgcctcttacggattttcaaagtgaccaggcactggacatccctgagcaacttggtg
gcatccttgttaaactccatgaagtccatcgcttcactgttgcttctgcttttcctcttc
atcattatcttctccttgcttgggatgcagctgtttggcggcaagtttaattttgacgag
acgcagaccaagcggagcacctttgacaacttccctcaggcactcctaacagtgttccag
attctgacaggcgaagattggaatgcggtgatgtatgacggcattatggcgtacgggggc
ccgtcatcttcaggaatgatcgtctgcatctacttcatcatcctcttcatttgtgggaac
tatatcctcctgaatgtcttcttggccatcgctgtggacaatttggctgacgctgaaagt
ctgaatactgctcagaaagaggaagctgaagaaaaggaaaggaaaaagattgccaggaaa
gaaagcctggaaaataaaaagaacaacaagccggaagtcaatcagatagccaacagtgac
aacaaggttacaattgatgactaccgagaagaggatgaggacaaggacccctacccacct
tgcgatgtgccagtagatgaagaggaagaggaagaggaggaggaggatgagcccgaggtt
cctgctggcccccgtcctcgcagaatctcggagttgaacatgaaagagaaaatcatcccc
attcctgaagggagcgctttcttcattcttagcaagaccaacccgatccgtgtgggctgc
cacaagctcatcaaccaccacatcttcaccaacctcatcctcgtcttcatcatgctgagc
agtgcgtccctcgccgctgaggaccccatccgcagccactccttccggaacattatactg
ggttacttcgactatgttttcacagccatctttactattgaaatcctgttaaagatgacg
acttttggagctttcctccacaaaggagccttctgcaggaactacttcaatctgctggac
atgctggtggtcggggtctctctggtatcatttgggatccaatccagcgccatctccgtt
gtgaagatactcagggtcttaagggtcctgaggccgctcagggcaatcaatagagcgaaa
ggacttaagcatgtcgtccagtgtgtctttgtggccatccggacaattggcaacatcatg
atcgtcaccacccttctccagttcatgtttgcctgcatcggggtccagttgttcaaggga
aagttctatcgctgcaccgatgaagccaaaagtaaccctgaggaatgcagggggcttttc
attctctacaaggatgaggatgttgataaccctgtggtccgtgagaggatctggcaaaat
agcgatttcaattttgacaatgtcctttctgctatgatggcgctgttcacagtctccacg
tttgagggttggcctgagttgctgtacaaagccattgactcgaatggagagaatgtcggc
ccaatctacaactaccgagtagagatctccatcttcttcatcatctacatcatcatcgtc
gctttcttcatgatgaacatcttcgtgggtttcgtcattgtcacattccaggagcaggga
gaaaaagagtataagaactgtgagctggacaaaaatcagcgtcagtgtgttgaatacgcc
ttgaaagcacgtcccttgcggagatacatccccaaaaacccctaccagtacaagttctgg
tacgtggtgaactcctcgcctttcgaatacgtgatgtttgtcctcatcatgctcaacaca
ctctgcttggccatgcagcactacgagcagtccaagatgtttaatgacgccatggacatt
ctcaacatggtcttcactggggtgttcactgtcgagatggttttgaaagtcattgcattt
aaacctaaggggtattttagtgacgcctggaatacgtttgactccctcatcgtaatcggc
agcattatagacgtggccctcagcgaagccgacccaaatgaaagtgaaaatgtccctgtc
ccaactgctacacctgggaactctgaagagagcaatagaatctccatcacctttttccgt
cttttccgagtgatgcgattggtgaagcttctcagcaggggggaaggcatccggacattg
ctgtggacttttattaagtcctttcaggcgcttccgtatgttgccctcctcatagccatg
ttgttcttcatctacgcagtgattggcatgcagatgtttgggaaagttgccatgagagat
aacaaccagatcaacaggaacaacaatttccagacctttccccaggcggtgctgctgctc
ttcaggtgtgcgacaggtgaggcctggcaggagatcatgctggcctgcctcccggggaag
ctctgtgaccccgagtcggattacaaccctggggaggagtactcctgtgggagcaacttc
gccatcgtgtatttcatcagtttttacatgctctgcgcgtttctgatcatcaacctgttt
gtggctgtcatcatggataactttgattacctgacccgggactggtctattctgggacct
caccacttagatgaattcaaaagaatatggtcagaatatgaccccgaggcaaagggaagg
atcaagcacctggacgtggtcaccctgcttcgccgcatccagcctcccctggggtttggg
aaattatgcccacacagagtagcctgtaagagactagttgccatgaacatgcctctcaac
agtgacgggacagtcatgtttaatgcgaccctgtttgccttggttcgaacagctcttaaa
atcaagaccgaagggaacctggaacaagctaatgaagaactccgagctgtgataaagaaa
atctggaagaaaaccagcatgaaactacttgaccaggtcgtcccaccagctggtgatgat
gaggtaaccgtggggaagttctatgccactttcctgatacaggactactttaggaaattc
aagaaacggaaagaacaaggactggtgggaaaataccctgcgaagaacaccacaattgcc
ctacaggcggggttaaggacactgcacgacatcgggccagagatccggcgtgccatatcc
tgtgatctgcaagatgatgagcccgaggaaacaaaaggagaagaagaagatgtattcaaa
agaaatggtgccctgcttggaaaccatgtcaatcatgttaatagtgataggagagattcc
cttcagcagaccaataccacccaccgtcccctgcatgtccaaaggccttcagttccacct
gcaagtgatactgagaaaccgctgtttcctccagcaggaaattcggtgtgtcataaccat
cataaccataattccataggaaagcaagttcccagctcaacaaatgccaatctcaataat
gccaatatgtccaaagctgcccctggaaagcggcccagcattgggaaccttgagcatgtg
tctgaaaatgagcatgagtcctcccacaagcttgaccatgagcctcaaagaaggtccagt
attaaaagaacccgctattatgaaacttatattaggtcggactcaggagacgagcagttc
ccaactatttgccgggaagaccctgatatacacagctacttcagggaaccccactgcttg
ggggagccggagtacttcagtggtgaggaggactacgaggacgacagctcgccgacctcc
agcaggcacaattatagctactacaaccgatacccaggcagcaacttggacttcgagcgg
ccccgaggctaccatcaccctcaaggcttcttggaggacgatgactcacccatttgctat
gattcccggagatctccaaggagacgcctactacctcccaccccaacatcccaccgaaga
tcctccttcaattttgagtgcctgcgccggcagagcagccaggaggaggtcccagtgtca
ccggccttccctcaccgtaccgccctgcctctacacctgatgcagcaacaggtcatggca
gttgcaggcctcgattcaagtaaagcccagaaatactcgccaagccactccacccggtca
tgggccacgcccccagcgacccctccgtaccgggactggacgccatgctacacccccctg
atccaggtggagcagtcggaggccctggaccaggtcaatggcagcctgccttccctgcac
cgcagctcgtggtacacggacgagcctggcatctcctatcggactttcacgccagccagc
ctgactgtccccagcagcttccacaacaaaaacagcgacaagcagaggagcgcagacagc
ttggtggaggcagtcctgatatctgaaggcttaggacggtatgcaagggaccccaaattt
gtgtcagcaacaaaacacgaaattgctgatgcctgtgacctaaccattgacgagatggag
agtgcagccagcaacttgcttaatggaaccatgcatccccgggctaacggggacctgggc
cctgtctcaagccggcaggactacgagctccaggacttcgggccaggctacagtgacgaa
gagccagaccttgggagagaggaggaggacctggcggatgaaatgatatgcatcaccacc
ctgtag

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (35)   
   KEGG PATHWAY (35)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (5)   
   RefSeq(pep) (5)   
DNA sequence (5)   
   RefSeq(nuc) (5)   
Protein domain (5)   
   Pfam (5)   
All databases (56)   

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