KEGG   Desmodus rotundus (common vampire bat): 112308621
Entry
112308621         CDS       T05907                                 
Symbol
MAP2K3
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 3
  KO
K04432  mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
Organism
dro  Desmodus rotundus (common vampire bat)
Pathway
dro04010  MAPK signaling pathway
dro04015  Rap1 signaling pathway
dro04218  Cellular senescence
dro04620  Toll-like receptor signaling pathway
dro04664  Fc epsilon RI signaling pathway
dro04668  TNF signaling pathway
dro04714  Thermogenesis
dro04750  Inflammatory mediator regulation of TRP channels
dro04912  GnRH signaling pathway
dro04935  Growth hormone synthesis, secretion and action
dro04936  Alcoholic liver disease
dro05014  Amyotrophic lateral sclerosis
dro05022  Pathways of neurodegeneration - multiple diseases
dro05132  Salmonella infection
dro05135  Yersinia infection
dro05145  Toxoplasmosis
dro05161  Hepatitis B
dro05169  Epstein-Barr virus infection
dro05170  Human immunodeficiency virus 1 infection
dro05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
dro05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:dro00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    112308621 (MAP2K3)
   04015 Rap1 signaling pathway
    112308621 (MAP2K3)
   04668 TNF signaling pathway
    112308621 (MAP2K3)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    112308621 (MAP2K3)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    112308621 (MAP2K3)
   04664 Fc epsilon RI signaling pathway
    112308621 (MAP2K3)
  09152 Endocrine system
   04912 GnRH signaling pathway
    112308621 (MAP2K3)
   04935 Growth hormone synthesis, secretion and action
    112308621 (MAP2K3)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    112308621 (MAP2K3)
  09159 Environmental adaptation
   04714 Thermogenesis
    112308621 (MAP2K3)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    112308621 (MAP2K3)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    112308621 (MAP2K3)
   05161 Hepatitis B
    112308621 (MAP2K3)
   05169 Epstein-Barr virus infection
    112308621 (MAP2K3)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    112308621 (MAP2K3)
   05135 Yersinia infection
    112308621 (MAP2K3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    112308621 (MAP2K3)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    112308621 (MAP2K3)
   05022 Pathways of neurodegeneration - multiple diseases
    112308621 (MAP2K3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    112308621 (MAP2K3)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    112308621 (MAP2K3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:dro01001]
    112308621 (MAP2K3)
Enzymes [BR:dro01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     112308621 (MAP2K3)
Protein kinases [BR:dro01001]
 Serine/threonine kinases: STE group
  STE7 family
   112308621 (MAP2K3)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Seadorna_VP7 Haspin_kinase Pkinase_fungal APH Choline_kinase RIO1 DUF4344
Other DBs
NCBI-GeneID: 112308621
NCBI-ProteinID: XP_024420692
Position
Unknown
AA seq 347 aa
MESPASSQPAGIPQSKGKSKRKKDLHISCVSKPPVPNPTPPRNLDSRAFITIGDRNFEVE
ADDLVTISELGRGAYGVVEKVRHTQSGTILAVKRIRATVNSQEQKRLLMDLDVNMRTVDC
FYTVTFYGALFREGDVWICMELMDTSLDKFYRKVLDKNMTIPEDILGKIAVSIVRALEHL
HSKLSVIHRDVKPSNVLINKEGHVKMCDFGISGYLVDSVAKTLDAGCKPYMAPERINPEL
NQKGYNVKSDVWSLGITMIEMAILRFPYGSWGTPFQQLKQVVEEPSPQLPADRFSPEFVD
FTAQCLRKNPTERMSYLELMEHPFFILHKTKKTDIAAFVKEILGEDS
NT seq 1044 nt   +upstreamnt  +downstreamnt
atggaatcccccgcctccagccaacctgctggcataccacagtccaaaggaaaatccaag
aggaagaaggacttacatatatcctgtgtgtccaagccgcccgtgcccaaccccaccccc
cccaggaaccttgattcccgggccttcatcaccattggagacaggaactttgaggtagag
gccgatgacctggtgaccatctcggagctggggcgcggagcctatggggtggtggagaaa
gtacggcacacccagagtggcaccatcttggctgttaagcggatccgggccaccgtgaac
tcccaggagcagaagcgtctgcttatggacttggatgtgaacatgcgcacggttgactgc
ttctacactgtcaccttctatggggccctcttcagagagggagatgtgtggatctgcatg
gaactcatggacacatccctggacaagttctaccgtaaggttcttgataaaaacatgacg
attccagaggacattctggggaagattgctgtgtctattgtgagggcactggagcacctg
cacagcaagctgtctgtgattcacagagatgtaaagccatctaatgtcctcatcaacaag
gaggggcatgtgaagatgtgtgactttgggatcagtggctacttggtagattctgtggcc
aagacgctggatgctggttgcaagccctacatggctccggagagaatcaacccagaactg
aaccagaagggctacaacgttaagtccgacgtctggagcctcggcattaccatgattgag
atggctatcctacggtttccttatgggtcctgggggaccccattccagcagctgaaacag
gtggtggaggagccgtccccccagctcccagctgaccgtttctctcctgagtttgtggac
ttcactgcacaatgcctgaggaagaaccccaccgaacgcatgagctaccttgagttgatg
gagcatcctttcttcatcttgcacaaaaccaagaagacagacatcgctgcttttgtgaag
gagatcctaggagaggactcatag

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (21)   
   KEGG PATHWAY (21)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (3)   
   RefSeq(pep) (3)   
DNA sequence (5)   
   RefSeq(nuc) (3)   
   GenBank (1)   
   EMBL (1)   
Protein domain (11)   
   Pfam (11)   
All databases (48)   

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