KEGG   Desmodus rotundus (common vampire bat): 112311145
Entry
112311145         CDS       T05907                                 

Gene name
HIF1A
Definition
(RefSeq) hypoxia-inducible factor 1-alpha
  KO
K08268  hypoxia-inducible factor 1 alpha
Organism
dro  Desmodus rotundus (common vampire bat)
Pathway
dro04066  HIF-1 signaling pathway
dro04137  Mitophagy - animal
dro04140  Autophagy - animal
dro04659  Th17 cell differentiation
dro04919  Thyroid hormone signaling pathway
dro05167  Kaposi sarcoma-associated herpesvirus infection
dro05200  Pathways in cancer
dro05205  Proteoglycans in cancer
dro05211  Renal cell carcinoma
dro05230  Central carbon metabolism in cancer
dro05231  Choline metabolism in cancer
dro05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:dro00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04066 HIF-1 signaling pathway
    112311145 (HIF1A)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    112311145 (HIF1A)
   04137 Mitophagy - animal
    112311145 (HIF1A)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    112311145 (HIF1A)
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    112311145 (HIF1A)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    112311145 (HIF1A)
   05205 Proteoglycans in cancer
    112311145 (HIF1A)
   05230 Central carbon metabolism in cancer
    112311145 (HIF1A)
   05231 Choline metabolism in cancer
    112311145 (HIF1A)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    112311145 (HIF1A)
  09162 Cancer: specific types
   05211 Renal cell carcinoma
    112311145 (HIF1A)
  09172 Infectious disease: viral
   05167 Kaposi sarcoma-associated herpesvirus infection
    112311145 (HIF1A)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:dro03000]
    112311145 (HIF1A)
Transcription factors [BR:dro03000]
 Eukaryotic type
  Basic helix-loop-helix (bHLH)
   Factors with PAS domain
    112311145 (HIF1A)
SSDB
Motif
Pfam: PAS_3 HIF-1a_CTAD PAS_11 HIF-1 PAS PAS_9 PAS_4 HLH DDRGK
Other DBs
NCBI-GeneID: 112311145
NCBI-ProteinID: XP_024423159
Position
Unknown
AA seq 823 aa
MEGAGGANDKKKISSERRKEKSRDAARSRRSKESEVFYELAHQLPLPHNVSSHLDKASVM
RLTISYLRVRKLLDAGDLDIEDEMKAQMNCFYLKALDGFVMVLTDDGDMIYISDNVNKYM
GLTQFELTGHSVFDFTHPCDHEEMREMLTHRNGLVKKGKEQNTQRSFFLRMKCTLTSRGR
TMNIKSATWKVLHCTGHIHVYDTNGNQSQCGYKKPPMTCLVLICEPIPHPSNIEIPLDSK
TFLSRHSLDMKFSYCDERITELMGYEPEELLGRSIYEYYHALDSDHLTKTHHDMFTKGQV
TTGQYRMLAKRGGYVWVETQATVIYNTKNSQPQCIVCVNYVVSGIIQHDLIFSLQQTECV
LKPVESSDMKMTQLFTKVESEDTSSLFDKLKKEPDALTLLAPAAGDTIISLDFGSNDTET
DDQQLEEVPLYNDVMLPSSNERLQNINLAMSPLPASETPEPLRSSADPALNQEVALKLEP
NPESLELSFTMPQIQDQPASPSDGSTRQSSPEPTSPSEYCFDVDSDMVNEFKLELVEKLF
AEDTEAKNPFSTQDTDLDLEMLAPYIPMDDDFQLRSFDQLSPLESSSTSPQSTSTISAFQ
PTQMQEPTLTATTTAATTDELKTLTKDGMEDIKILIASPSPTHIPKETTSTTTSPYSDTR
SRTASPNRAGKGVIEQTEKSHPRSPNVLSITLSQRTTVPEEELNPKILALQNAQRKRKIE
HDGSLFQAVGIGTLLQQPDDRATTTSLSWKRVKGCRSSEQNGMEQKTIILIPSDLACRLL
GQSMDESGLPQLTSYDCEVNAPIQGSRNLLQGEELLRALDQVN
NT seq 2472 nt   +upstreamnt  +downstreamnt
atggagggcgccggaggcgcgaacgacaagaaaaagataagttctgaacgtcgaaaagaa
aagtctagagatgcagccagatctcggcgaagtaaagagtctgaagttttttatgagctt
gctcatcagttgccacttccccataatgtgagttcgcatcttgataaggcttctgttatg
aggcttaccatcagctatttgcgtgtgaggaaacttctcgatgctggtgatttggatatt
gaagatgaaatgaaagcacaaatgaattgcttttatttgaaagccctggatggttttgtt
atggttctcacagatgatggtgatatgatttacatttctgataatgtgaataaatacatg
gggttaacgcagtttgaactaactggacacagtgtgtttgattttactcatccgtgtgac
catgaggaaatgagagaaatgcttacacacagaaatggccttgtaaaaaaaggtaaagag
caaaatacacagcgaagcttttttctcagaatgaagtgtaccctgactagccgggggaga
actatgaacatcaagtctgcaacatggaaggtacttcattgcacaggacatattcatgtg
tacgataccaatggtaaccagtctcaatgtgggtataagaaaccacctatgacgtgcttg
gtgctcatttgtgaacccattcctcatccgtcaaatattgaaattccattagatagcaag
actttcctcagtcgtcacagtctggatatgaaattttcttattgtgatgaaagaattact
gaattgatggggtatgagccagaagaacttttgggccgctcaatttatgaatattatcat
gctttggactctgatcatctgaccaaaactcatcatgacatgtttactaaaggacaagtc
accacaggacagtaccggatgcttgccaaaagaggtggatatgtctgggttgaaactcaa
gccactgtcatatataacactaagaactctcaaccacaatgcattgtatgtgtaaattat
gttgtgagtggtattattcaacacgacttgatcttctcccttcaacaaacagaatgtgtc
ctgaaaccagttgaatcttcagatatgaaaatgactcagctgttcaccaaagttgaatca
gaagatacaagtagcctctttgataaacttaagaaggaacctgatgctttaactttgctg
gccccagctgctggagacacaatcatatctttagattttggcagcaatgacacagaaact
gatgaccaacaacttgaggaagttccattatataatgatgtaatgctcccctcatctaat
gaaagattacagaatataaatttggcaatgtctccattacctgcctctgaaactccagag
ccacttcgaagtagtgctgaccctgcactcaatcaggaagttgcgttaaaattagaacca
aatccagagtcactggaactgtcttttactatgccccagattcaagatcagccagctagt
ccttctgatggaagcactagacaaagttcacctgagcctaccagtccgagtgaatattgt
tttgatgtggatagtgatatggtcaatgaattcaagttggaattggtagagaaacttttt
gctgaagacacggaagcaaagaatccattttctactcaggacactgacttagacttggag
atgttagctccttatatcccaatggatgatgacttccagttacgttcctttgatcagttg
tcaccattggaaagcagttctacaagcccccaaagtacaagcacaatctcagcattccag
ccaactcaaatgcaagaaccaactcttaccgccaccactaccgctgccaccactgatgaa
ttaaaaacactgacaaaagatggtatggaagacattaaaatattgattgcatctccatct
cctacccacatacctaaagaaactactagtaccacaacatcaccatatagtgatactcga
agtcggacagcctcaccaaacagagcaggaaaaggagtgatagaacaaacagaaaaatct
catccaagaagccctaacgtgttatctatcactttgagtcaaagaactactgttcctgag
gaagaactaaatccaaagatactagctttgcagaatgctcaaagaaaacgaaaaatagaa
catgatggttcactttttcaagcagtaggaattggaacattattacagcagccagatgat
cgtgcaactactacatcactttcttggaaacgcgtaaaaggatgcagatctagtgaacag
aatggaatggagcaaaagactattattttaataccctctgatttagcatgtagactgctg
gggcaatcaatggatgagagtggattaccacagctgaccagctatgattgtgaagtcaac
gctcctatacaaggcagcagaaacctactgcagggtgaagaattactcagagcattggat
caagttaactga

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