KEGG   Desmodus rotundus (common vampire bat): 112321823
Entry
112321823         CDS       T05907                                 

Gene name
PTPN6
Definition
(RefSeq) tyrosine-protein phosphatase non-receptor type 6 isoform X1
  KO
K05697  tyrosine-protein phosphatase non-receptor type 6 [EC:3.1.3.48]
Organism
dro  Desmodus rotundus (common vampire bat)
Pathway
dro04520  Adherens junction
dro04630  JAK-STAT signaling pathway
dro04650  Natural killer cell mediated cytotoxicity
dro04660  T cell receptor signaling pathway
dro04662  B cell receptor signaling pathway
dro05140  Leishmaniasis
dro05205  Proteoglycans in cancer
dro05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:dro00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    112321823 (PTPN6)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    112321823 (PTPN6)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    112321823 (PTPN6)
   04660 T cell receptor signaling pathway
    112321823 (PTPN6)
   04662 B cell receptor signaling pathway
    112321823 (PTPN6)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    112321823 (PTPN6)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    112321823 (PTPN6)
  09174 Infectious disease: parasitic
   05140 Leishmaniasis
    112321823 (PTPN6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:dro01009]
    112321823 (PTPN6)
Enzymes [BR:dro01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.48  protein-tyrosine-phosphatase
     112321823 (PTPN6)
Protein phosphatases and associated proteins [BR:dro01009]
 Protein tyrosine phosphatases (PTPs)
  Class I PTPs (Classical)
   Non-receptor PTPs
    112321823 (PTPN6)
SSDB
Motif
Pfam: Y_phosphatase SH2 DSPc Y_phosphatase3 PTPlike_phytase
Other DBs
NCBI-GeneID: 112321823
NCBI-ProteinID: XP_024435170
Position
Unknown
AA seq 597 aa
MLSHGWFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQNSG
DFYDLYGGEKFATLTELVEYYTQQHGVLQDRDGTIIHLKYPLNCSDPTSERWYHGHMSGG
QAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPLKVTHIKVMCEGGRYTV
GGSETFDSLTDLVEHFKKTGIEEASGAFVYLRQPYYATRVNAADIENRVLELNKKQESED
TAKAGFWEEFESLQKQEVKNLHERLEGQRPENKSKNRYKNILPFDHSRVILQGRDSNIPG
SDYINANYIKNQLLGPDENAKTYIASQGCLDATVNDFWQMIWQENSRVVVMTTREVEKGR
NKCVPYWPEVGTQRVYGPYTVTSCGEHDTAEYKLRTLQVSPLDNGNLVREIWHYQYLSWP
DHGVPSEPGGVLSFLDQVNQRQESLPHAGPIIVHCSAGIGRTGTIIVIDMLMESISTKGL
DCDIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEVMQSQKGQESEYGN
ISYPPAMKNAHAKAFRTSSKHKEDVYENLQSKNKREEKVKKQRSADKDKSKGSLKRK
NT seq 1794 nt   +upstreamnt  +downstreamnt
atgctgtctcatgggtggtttcatcgagacctcagtgggctggacgcagagaccctgctc
aagggccgaggtgtccacgggagtttcctggctcggcccagtcgtaagaaccagggcgac
ttctccctttccgtcagggtaggggatcaggtgacccacattcgcatccagaactcaggg
gatttctacgacctgtatggaggggagaagtttgcgacactgacggagctggtggagtac
tacacgcagcagcacggcgtcctccaggaccgcgatggcaccatcatccacctcaagtac
ccgcttaactgctctgaccctaccagtgagaggtggtaccatggccacatgtctgggggg
caggcggagacactgctgcaggccaagggtgagccctggacatttctcgtgcgtgagagt
ctcagccagcctggagattttgtgctgtccgtgctcagtgaccaacccaaggctggtcca
ggctccccactcaaagtcacccatatcaaggtcatgtgtgagggcggacgctacacagtg
ggtggttcagagacctttgacagcctcacggacctggtggagcatttcaagaagacgggg
attgaggaggcctcgggtgcctttgtctacctgcggcagccatactacgccacacgggtg
aatgcagctgacattgagaaccgggtcttggaactgaacaagaagcaggagtcggaggat
acagccaaggccggcttctgggaggagtttgagagtctgcagaagcaggaggtgaagaac
ctgcatgagcggctggaagggcagcggccagagaacaagagcaagaaccgttacaagaac
attctccccttcgaccacagccgagtgatcctgcagggacgtgacagtaacatccctggg
tctgactacatcaatgccaactacatcaagaaccagctgctaggccctgatgagaatgct
aagacctacatcgccagccagggctgcctggacgccacggtcaacgacttctggcagatg
atatggcaggagaacagccgtgtcgtcgtcatgaccacccgggaggtggagaaaggccgg
aacaaatgtgtcccatattggccagaggtgggcactcagcgtgtgtatggaccctacact
gtaaccagctgtggggaacacgacacagctgagtacaaacttcgcaccttacaggtctcc
ccgctggacaatgggaacctggtgcgggagatctggcactaccagtacctgagctggcct
gaccacggtgtccccagcgagcctgggggtgtcctcagcttcctggaccaggtcaatcag
cggcaggaaagtctgcctcatgcagggcccatcattgtgcattgcagcgcgggcatcggc
cgcacaggcaccatcatcgtcatcgacatgctcatggagagcatctccaccaaagggctg
gactgcgatattgacatccagaagacaatccagatggtgcgggcacagcgctcaggcatg
gtgcagacggaggcacagtacaagttcatctatgtggccatcgcccagttcattgaaacc
accaagaagaagctggaggtcatgcagtcccagaagggccaggagtcagagtacgggaac
atctcttacccccccgccatgaagaacgcccatgccaaggcctttcgcacctcttccaaa
cacaaggaggatgtgtatgagaacctacagagtaagaacaagagggaggagaaggtgaag
aagcagcggtcagcggacaaggacaagagcaagggctccctcaagaggaagtga

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