Entry |
|
Name |
Colistin (INN); Sogecoli (TN) |
Formula |
C52H97N16O13R
|
Structure |
|
Source |
Bacillus polymyxa var. colistinus
|
Class |
Antibacterial
DG01579 Polypeptide antibiotic
|
Remark |
Product (DG00087): | D02049<JP/US> |
|
Efficacy |
Antibacterial, Cell membrane function inhibitor |
Comment |
Natural product
Polypeptide
|
Target |
Lipopolysaccharide |
Interaction |
|
Other map |
map01503 | Cationic antimicrobial peptide (CAMP) resistance |
|
Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A07 ANTIDIARRHEALS, INTESTINAL ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS
A07A INTESTINAL ANTIINFECTIVES
A07AA Antibiotics
A07AA10 Colistin
D07746 Colistin (INN)
J ANTIINFECTIVES FOR SYSTEMIC USE
J01 ANTIBACTERIALS FOR SYSTEMIC USE
J01X OTHER ANTIBACTERIALS
J01XB Polymyxins
J01XB01 Colistin
D07746 Colistin (INN)
Risk category of Japanese OTC drugs [BR:br08312]
Second-class OTC drugs
Inorganic and organic chemicals
Colistin
D07746 Colistin (INN)
Drug groups [BR:br08330]
Antibacterial
DG01579 Polypeptide antibiotic
DG00087 Colistin
D07746 Colistin
Antimicrobials [BR:br08307]
Antibacterials
Cell membrane function inhibitor
Polypeptide
D07746 Colistin (INN)
Drug groups [BR:br08330]
Antibacterial
DG01579 Polypeptide antibiotic
DG00087 Colistin
Antimicrobials abbreviations [BR:br08327]
Antibacterials
Cell membrane function inhibitor
Polypeptide
DG00087 Colistin
|
Other DBs |
|
KCF data |
ATOM 82
1 C1c C 34.4400 -24.2900
2 C1a C 35.6300 -24.9900
3 O1a O 33.1800 -24.9900
4 C1c C 30.8000 -16.3800
5 N1b N 30.8000 -17.7800
6 N1b N 33.1800 -16.3800
7 C5a C 31.9900 -15.6800
8 C5a C 35.6300 -16.3800
9 C1c C 34.4400 -15.6800
10 C1c C 38.0800 -16.3800
11 N1b N 36.8200 -15.6800
12 C5a C 29.5400 -18.4100
13 C1c C 29.5400 -19.8100
14 C1b C 30.8000 -20.5800
15 C1b C 30.8000 -21.9800
16 N1b N 31.9900 -22.6100
17 C5a C 33.1800 -21.9800
18 C1c C 34.4400 -22.6100
19 N1b N 35.6300 -21.9800
20 C5a C 36.8200 -22.6100
21 C1c C 38.0800 -21.9800
22 O5a O 31.9900 -14.2800
23 C1c C 40.4600 -16.3800
24 C1b C 39.2700 -15.6800
25 C1b C 34.4400 -14.0000
26 C5a C 38.0800 -17.7800
27 C1a C 41.7200 -15.6800
28 C1a C 40.4600 -17.7800
29 O5a O 36.8200 -18.4100
30 C1c C 35.6300 -13.3000
31 C1a C 36.8900 -14.0000
32 C1a C 35.6300 -11.8300
33 O5a O 35.6300 -17.7800
34 C1b C 29.5400 -15.6800
35 O5a O 28.3500 -17.7800
36 N1b N 28.3500 -20.5800
37 O5a O 33.1800 -20.5800
38 O5a O 36.8200 -24.0100
39 N1b N 38.0800 -20.5800
40 C5a C 39.4800 -20.5800
41 N1b N 39.2700 -18.4100
42 C1c C 40.1800 -19.3900
43 C1b C 41.5800 -19.3900
44 C1b C 39.2700 -22.6100
45 C1b C 39.2700 -24.0100
46 N1a N 40.4600 -24.7100
47 C1b C 29.5400 -14.2800
48 N1a N 28.3500 -13.5800
49 C5a C 27.1600 -19.8100
50 C1c C 25.9000 -20.5800
51 N1b N 24.7100 -19.8100
52 C5a C 23.5200 -20.5800
53 C1c C 22.2600 -19.8100
54 N1b N 21.0700 -20.5800
55 C5a C 19.8800 -19.8100
56 C1c C 18.6200 -20.5800
57 N1b N 17.4300 -19.8100
58 C5a C 16.2400 -20.5800
59 C1b C 15.0500 -19.8100
60 C1b C 13.7900 -20.5800
61 C1b C 12.6000 -19.8100
62 C1b C 11.3400 -20.5800
63 C1c C 10.1500 -19.8100
64 C1b C 8.9600 -20.5800
65 R R 7.7700 -19.8100
66 O5a O 27.1600 -18.4100
67 C1b C 25.9000 -21.9800
68 O5a O 23.5200 -21.9800
69 C1c C 22.2600 -18.0600
70 C1a C 21.0700 -17.4300
71 O1a O 23.5200 -17.4300
72 O5a O 19.8800 -18.4100
73 C1b C 18.6200 -21.9800
74 O5a O 16.2400 -21.9800
75 C1a C 10.1500 -18.4100
76 C1b C 24.7100 -22.6100
77 N1a N 24.7100 -24.0100
78 C1b C 17.4300 -22.6100
79 N1a N 17.4300 -24.0100
80 O5a O 40.1800 -21.7700
81 C1b C 42.2800 -20.5800
82 N1a N 43.6800 -20.5800
BOND 82
1 1 2 1
2 1 3 1
3 17 18 1
4 18 19 1
5 19 20 1
6 20 21 1
7 7 22 2
8 23 24 1
9 10 24 1
10 9 25 1
11 10 26 1
12 23 27 1
13 23 28 1
14 26 29 2
15 25 30 1
16 30 31 1
17 30 32 1
18 8 33 2
19 4 34 1
20 12 35 2
21 13 36 1
22 17 37 2
23 20 38 2
24 21 39 1
25 39 40 1
26 26 41 1
27 40 42 1
28 41 42 1
29 42 43 1
30 21 44 1
31 44 45 1
32 45 46 1
33 34 47 1
34 47 48 1
35 36 49 1
36 49 50 1
37 50 51 1
38 51 52 1
39 52 53 1
40 53 54 1
41 54 55 1
42 55 56 1
43 56 57 1
44 57 58 1
45 58 59 1
46 59 60 1
47 60 61 1
48 61 62 1
49 62 63 1
50 63 64 1
51 64 65 1
52 49 66 2
53 50 67 1
54 52 68 2
55 53 69 1
56 69 70 1
57 69 71 1
58 55 72 2
59 56 73 1
60 58 74 2
61 63 75 1
62 67 76 1
63 76 77 1
64 73 78 1
65 78 79 1
66 40 80 2
67 4 5 1
68 6 7 1
69 4 7 1
70 8 9 1
71 6 9 1
72 10 11 1
73 8 11 1
74 5 12 1
75 12 13 1
76 13 14 1
77 14 15 1
78 15 16 1
79 16 17 1
80 1 18 1
81 43 81 1
82 81 82 1
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