KEGG   DRUG: GlucagonHelp
Entry
D00116                      Drug                                   

Name
Glucagon (JAN/USP/INN);
Glucagon (genetical recombination) (JAN);
Glucagon (TN)
Product
Formula
C153H225N43O49S
Exact mass
3480.6157
Mol weight
3482.7473
Sequence
His Ser Gln Gly Thr Phe Thr Ser Asp Tyr Ser Lys Tyr Leu Asp Ser
Arg Arg Ala Gln Asp Phe Val Gln Trp Leu Met Asn Thr
  Type
Peptide
Remark
Same as: C01501
Therapeutic category: 2492 7229
ATC code: H04AA01
Chemical structure group: DG00511
Product (DG00511): D00116<JP/US> D02118<US>
Efficacy
Antidiabetic, Diagnostic, Glucagon receptor agonist
Comment
Glucagon is a single-chain polypeptide that contains 29 amino acid residues.
Target
GCGR [HSA:2642] [KO:K04583]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04922  Glucagon signaling pathway
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 H SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
  H04 PANCREATIC HORMONES
   H04A GLYCOGENOLYTIC HORMONES
    H04AA Glycogenolytic hormones
     H04AA01 Glucagon
      D00116  Glucagon (JAN/USP/INN) <JP/US>
USP drug classification [BR:br08302]
 Blood Glucose Regulators
  Glycemic Agents
   Glucagon
    D00116  Glucagon (JAN/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  24  Hormones
   249  Miscellaneous
    2492  Pancreatic hormones
     D00116  Glucagon (JAN/USP/INN); Glucagon (genetical recombination) (JAN)
 7  Agents not mainly for therapeutic purpose
  72  Intracorporeal diagnostic agents
   722  Various function testing reagents
    7229  Others
     D00116  Glucagon (JAN/USP/INN); Glucagon (genetical recombination) (JAN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Secretin receptor family
   Glucagon
    GCGR
     D00116  Glucagon (JAN/USP/INN) <JP/US>
BRITE hierarchy
Other DBs
CAS: 9007-92-5
PubChem: 7847184
ChEBI: 5391
DrugBank: DB00040
NIKKAJI: J9.063H

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