KEGG   DRUG: ZaltoprofenHelp
Entry
D01547                      Drug                                   

Name
Zaltoprofen (JP17/INN);
Zaltoprofen tablets (JP17);
CN 100;
Peon (TN)
Formula
C17H14O3S
Exact mass
298.0664
Mol weight
298.3563
Structure
Mol fileKCF fileDB search
Class
Anti-inflammatory
 DG01908  Antiinflammatory drug, propionic acid derivatives
 DG01504  Nonsteroidal antiinflammatory drug (NSAID)
  DG01908  Antiinflammatory drug, propionic acid derivatives
 DG01922  Selective COX2 inhibitor
Remark
Therapeutic category: 1149
Product: D01547<JP>
Efficacy
Analgesic, Anti-inflammatory, COX-2 inhibitor
Comment
Propionic acid derivative
Target
PTGS2 (COX2) [HSA:5743] [KO:K11987]
PTGS1 (COX1) [HSA:5742] [KO:K00509]
  Pathway
hsa00590  Arachidonic acid metabolism
Interaction
Drug interaction
Structure map
map07219  Cyclooxygenase inhibitors
Brite
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  11  Agents affecting central nervous system
   114  Antipyretics and analgesics, anti-inflammatory agents
    1149  Others
     D01547  Zaltoprofen (JP17/INN); Zaltoprofen tablets (JP17)
Target-based classification of drugs [BR:br08310]
 Enzymes
  Oxidoreductases (EC1)
   Prostaglandin synthase
    PTGS1 (COX1)
     D01547  Zaltoprofen (JP17/INN) <JP>
    PTGS2 (COX2)
     D01547  Zaltoprofen (JP17/INN) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D01547  Zaltoprofen
  D01547  Zaltoprofen tablets
Drug classes of therapeutic agents [br08360.html]
 Antirheumatic and antigout agents
  D01547
 Anesthetics, analgesics and anti-inflammatory drugs
  D01547
BRITE hierarchy
Other DBs
CAS: 74711-43-6
PubChem: 7848610
ChEBI: 32306
ChEMBL: CHEMBL1765291
LigandBox: D01547
NIKKAJI: J22.089B
KCF data Show

ATOM        21
            1   C5x C    26.4600  -23.7300
            2   C8y C    25.6200  -24.8500
            3   C8y C    25.9700  -26.1800
            4   S2x S    27.2300  -26.7400
            5   C1x C    27.8600  -23.7300
            6   C8y C    28.4900  -26.1100
            7   C8y C    28.7700  -24.7800
            8   C8x C    24.9200  -27.1600
            9   C8x C    23.5900  -26.7400
            10  C8x C    23.2400  -25.4100
            11  C8x C    24.2900  -24.4300
            12  C8x C    30.1000  -24.3600
            13  C8y C    31.1500  -25.2700
            14  C8x C    30.8700  -26.6700
            15  C8x C    29.5400  -27.0900
            16  O5x O    25.8300  -22.4700
            17  C1c C    32.3400  -24.5700
            18  C6a C    33.5300  -25.2700
            19  O6a O    33.5300  -26.6700
            20  C1a C    32.3400  -23.1700
            21  O6a O    34.7900  -24.5700
BOND        23
            1     3   4 1
            2     1   5 1
            3     4   6 1
            4     2   3 1
            5     5   7 1
            6     1   2 1
            7     6   7 1
            8     3   8 2
            9     8   9 1
            10    9  10 2
            11   10  11 1
            12    2  11 2
            13    7  12 2
            14   12  13 1
            15   13  14 2
            16   14  15 1
            17    6  15 2
            18    1  16 2
            19   13  17 1
            20   17  18 1
            21   18  19 2
            22   17  20 1
            23   18  21 1

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