| Entry |
|
|---|
| Name |
Doxylamine succinate (USP);
Decapryn (TN) |
|---|
| Formula |
C17H22N2O. C4H6O4
|
|---|
| Exact mass |
388.1998
|
|---|
| Mol weight |
388.4574
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
|
|---|
| Remark |
| Product (mixture): | D10357<US> |
|
|---|
| Efficacy |
Sedative-hypnotic, H1 receptor antagonist |
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04750 | Inflammatory mediator regulation of TRP channels |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07212 | Histamine H1 receptor antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
R RESPIRATORY SYSTEM
R06 ANTIHISTAMINES FOR SYSTEMIC USE
R06A ANTIHISTAMINES FOR SYSTEMIC USE
R06AA Aminoalkyl ethers
R06AA09 Doxylamine
D02327 Doxylamine succinate (USP)
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Histamine
HRH1
D02327 Doxylamine succinate (USP)
Rx-to-OTC switch list in the USA [br08315.html]
D02327
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 28
1 C1d C 25.8213 -16.7820
2 C8y C 24.6064 -17.4889
3 C8y C 27.0422 -17.4712
4 O2a O 25.8154 -15.3742
5 C8x C 24.6121 -18.8965
6 C8x C 23.3622 -16.8287
7 N5x N 28.2804 -16.8052
8 C8x C 27.0422 -18.8791
9 C1b C 26.9662 -14.6557
10 C8x C 23.4790 -19.6384
11 C8x C 22.1822 -17.5822
12 C8x C 29.4778 -17.5472
13 C8x C 28.2395 -19.6149
14 C8x C 22.1880 -18.9841
15 C8x C 29.4778 -18.9550
16 C1a C 24.6088 -16.0820
17 C1b C 28.1716 -15.3139
18 N1c N 29.3368 -14.6036
19 C1a C 30.5712 -15.2775
20 C1a C 29.3039 -13.2302
21 C1b C 35.6030 -17.1183
22 C1b C 36.8122 -16.4173
23 C6a C 34.3941 -16.4234
24 C6a C 38.0331 -17.1126
25 O6a O 33.1790 -17.1242
26 O6a O 34.3825 -15.0214
27 O6a O 39.2423 -16.4116
28 O6a O 38.0213 -18.5146
BOND 28
1 1 2 1
2 1 3 1
3 1 4 1
4 2 5 2
5 2 6 1
6 3 7 2
7 3 8 1
8 4 9 1
9 5 10 1
10 6 11 2
11 7 12 1
12 8 13 2
13 10 14 2
14 12 15 2
15 11 14 1
16 13 15 1
17 1 16 1
18 9 17 1
19 17 18 1
20 18 19 1
21 18 20 1
22 21 22 1
23 21 23 1
24 22 24 1
25 23 25 1
26 23 26 2
27 24 27 1
28 24 28 2
|
|---|
