| Entry |
|
|---|
| Name |
Orphenadrine (INN);
Mialgin (TN) |
|---|
| Formula |
C18H23NO
|
|---|
| Exact mass |
269.1780
|
|---|
| Mol weight |
269.38
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
DG01745 Anticholinergic antiparkinson agent
Musculo-skeletal system agent
DG02029 Muscle relaxant
DG01974 Centrally acting muscle relaxant
|
|---|
| Remark |
| Product (DG01252): | D00774<US> |
|
|---|
| Efficacy |
Skeletal muscle relaxant, Muscarinic acetylcholine receptor antagonist, H1 receptor antagonist |
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07220 | Cholinergic and anticholinergic drugs |
|
|---|
| Brite |
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
DG01745 Anticholinergic antiparkinson agent
DG01252 Orphenadrine
D08305 Orphenadrine
Musculo-skeletal system agent
DG02029 Muscle relaxant
DG01974 Centrally acting muscle relaxant
DG01252 Orphenadrine
D08305 Orphenadrine
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Histamine
HRH1
D08305 Orphenadrine (INN)
Ion channels
Ligand-gated ion channels
Glutamate (ionotropic), NMDA
GRIN (NMDAR)
D08305 Orphenadrine (INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
DG01745 Anticholinergic antiparkinson agent
DG01252 Orphenadrine
Musculo-skeletal system agent
DG02029 Muscle relaxant
DG01974 Centrally acting muscle relaxant
DG01252 Orphenadrine
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 20
1 C1a C 19.3200 -19.3200
2 N1c N 20.5100 -18.6200
3 C1b C 21.7700 -19.3200
4 C1b C 22.9600 -18.6200
5 O2a O 24.1500 -19.3200
6 C1c C 25.4100 -18.6200
7 C8y C 26.6000 -19.3200
8 C8y C 25.4100 -17.2200
9 C8x C 26.6000 -16.5200
10 C8x C 26.6000 -15.1200
11 C8x C 25.3400 -14.4200
12 C8x C 24.1500 -15.1200
13 C8y C 24.1500 -16.5200
14 C8x C 26.6000 -20.7200
15 C8x C 27.7900 -21.4200
16 C8x C 29.0500 -20.7200
17 C8x C 29.0500 -19.3200
18 C8x C 27.7900 -18.6200
19 C1a C 22.9600 -17.2200
20 C1a C 20.5100 -17.2200
BOND 21
1 1 2 1
2 2 3 1
3 3 4 1
4 4 5 1
5 5 6 1
6 6 7 1
7 6 8 1
8 8 9 2
9 9 10 1
10 10 11 2
11 11 12 1
12 12 13 2
13 8 13 1
14 7 14 1
15 14 15 2
16 15 16 1
17 16 17 2
18 17 18 1
19 7 18 2
20 13 19 1
21 2 20 1
|
|---|
