KEGG   DISEASE: Klebsiella infectionHelp
Entry
H00301                      Disease                                

Name
Klebsiella infection
Description
Klebsiella is a gram-negative bacterium of Enterobacteriaceae with multidrug-resistance. They produce extended-spectrum beta-lactamase (ESBL) enzymes, making themselves resistant to antibiotic drugs. Klebsiella pneumoniae can cause sepsis, conjunctivitis, urinary tract infections, and surgical site infections. Bloodstream infections with Klebsiella markedly increase the rates of treatment failure and death.
Category
Infectious disease
Brite
Infectious diseases [BR:br08401]
 Bacterial infections
  Infections caused by enterobacteria
   H00301  Klebsiella infection
Human diseases in ICD-11 classification [BR:br08403]
 12 Diseases of the respiratory system
  Lung infections
   CA40  Pneumonia
    H00301  Klebsiella infection
BRITE hierarchy
Pathogen
Klebsiella pneumoniae [GN:kpn kpu kpm kpp kph kpz kpv kpw kpy kpg kpc kpq kpt kpr kpa kps kpx kpb kpnk]
Klebsiella aerogenes [GN:ear]
Klebsiella oxytoca [GN:koe kok]
Klebsiella quasipneumoniae [GN:kqu]
Other DBs
ICD-11: CA40.03
ICD-10: A49.8 B96.1 J15.0
MeSH: D007710
Reference
  Authors
Gupta N, Limbago BM, Patel JB, Kallen AJ
  Title
Carbapenem-resistant Enterobacteriaceae: epidemiology and prevention.
  Journal
Clin Infect Dis 53:60-7 (2011)
DOI:10.1093/cid/cir202
Reference
  Authors
Gupta A, Ampofo K, Rubenstein D, Saiman L
  Title
Extended spectrum beta lactamase-producing Klebsiella pneumoniae infections: a review of the literature.
  Journal
J Perinatol 23:439-43 (2003)
DOI:10.1038/sj.jp.7210973
Reference
  Authors
Tumbarello M, Spanu T, Sanguinetti M, Citton R, Montuori E, Leone F, Fadda G, Cauda R
  Title
Bloodstream infections caused by extended-spectrum-beta-lactamase-producing Klebsiella pneumoniae: risk factors, molecular epidemiology, and clinical outcome.
  Journal
Antimicrob Agents Chemother 50:498-504 (2006)
DOI:10.1128/AAC.50.2.498-504.2006
Reference
  Authors
Panhotra BR, Saxena AK, Al-Ghamdi AM
  Title
Extended-spectrum beta-lactamase-producing Klebsiella pneumoniae hospital acquired bacteremia. Risk factors and clinical outcome.
  Journal
Saudi Med J 25:1871-6 (2004)

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