KEGG   DISEASE: Klebsiella infection
H00301                      Disease                                

Klebsiella infection
Klebsiella is a gram-negative bacterium of Enterobacteriaceae, which has emerged as an important cause of hospital-acquired infections. Infections caused by extended-spectrum beta-lactamase (ESBL)-producing pathogens, particularly Klebsiella pneumoniae, are increasing. ESBL are plasmid-mediated enzymes and these plasmids also carry resistance genes to other antibiotics including aminoglycosides, chloramphenicol, sulfonamides, trimethoprim, and tetracycline. Thus, Gram-negative bacilli containing these plasmids are multidrug-resistant. Klebsiella pneumoniae can cause sepsis, conjunctivitis, urinary tract infections, and surgical site infections. Bloodstream infections with Klebsiella markedly increase the rates of treatment failure and death.
Infectious disease
Infectious diseases [BR:br08401]
 Bacterial infections
  Infections caused by enterobacteria
   H00301  Klebsiella infection
Human diseases in ICD-11 classification [BR:br08403]
 12 Diseases of the respiratory system
  Lung infections
   CA40  Pneumonia
    H00301  Klebsiella infection
Klebsiella pneumoniae [GN:kpn kpu kpm kpp kph kpz kpv kpw kpy kpg kpc kpq kpt kpr kpa kps kpx kpb kpnk]
Klebsiella oxytoca [GN:koe kok]
Klebsiella quasipneumoniae [GN:kqu]
Klebsiella aerogenes [GN:ear]
Klebsiella quasivariicola [GN:kqv]
Klebsiella sp. WCHKl090001 [GN:klw]
Other DBs
ICD-11: CA40.03
ICD-10: A49.8 B96.1 J15.0
MeSH: D007710
Gupta N, Limbago BM, Patel JB, Kallen AJ
Carbapenem-resistant Enterobacteriaceae: epidemiology and prevention.
Clin Infect Dis 53:60-7 (2011)
Gupta A, Ampofo K, Rubenstein D, Saiman L
Extended spectrum beta lactamase-producing Klebsiella pneumoniae infections: a review of the literature.
J Perinatol 23:439-43 (2003)
Tumbarello M, Spanu T, Sanguinetti M, Citton R, Montuori E, Leone F, Fadda G, Cauda R
Bloodstream infections caused by extended-spectrum-beta-lactamase-producing Klebsiella pneumoniae: risk factors, molecular epidemiology, and clinical outcome.
Antimicrob Agents Chemother 50:498-504 (2006)
Panhotra BR, Saxena AK, Al-Ghamdi AM
Extended-spectrum beta-lactamase-producing Klebsiella pneumoniae hospital acquired bacteremia. Risk factors and clinical outcome.
Saudi Med J 25:1871-6 (2004)

» Japanese version

DBGET integrated database retrieval system