KEGG   DISEASE: Multidrug-resistant Acinetobacter infectionHelp
Entry
H00309                      Disease                                

Name
Multidrug-resistant Acinetobacter infection
Description
Acinetobacter baumannii has emerged as a worldwide problem as a nosocomial pathogen in hospitalized patients. It can cause bacteremia, pneumonia, meningitis, urinary tract infection, wound infection, and nosocomial infections with mortality rates of 20 to 60%. Isolates resistant to almost all commercially available antimicrobials have been identified.
Category
Infectious disease
Brite
Infectious diseases [BR:br08401]
 Bacterial infections
  Infections caused by other gamma proteobacteria
   H00309  Multidrug-resistant Acinetobacter infection
Human diseases in ICD-11 classification [BR:br08403]
 21 Symptoms, signs or clinical findings, not elsewhere classified
  General symptoms, signs or clinical findings
   Finding of microorganism resistant to antimicrobial drugs
    MG50  Finding of gram negative bacteria resistant to antimicrobial drugs
     H00309  Multidrug-resistant Acinetobacter infection
BRITE hierarchy
Pathogen
Acinetobacter baumannii [GN:aby abc abn abx abz abr abd abh abad abk abau abaa]
Other DBs
ICD-11: MG50.0
ICD-10: A49.9
MeSH: D000151
Reference
PMID:18444865 (drug)
  Authors
Maragakis LL, Perl TM
  Title
Acinetobacter baumannii: epidemiology, antimicrobial resistance, and treatment options.
  Journal
Clin Infect Dis 46:1254-63 (2008)
DOI:10.1086/529198
Reference
PMID:16008625 (drug)
  Authors
Petrosillo N, Chinello P, Proietti MF, Cecchini L, Masala M, Franchi C, Venditti M, Esposito S, Nicastri E
  Title
Combined colistin and rifampicin therapy for carbapenem-resistant Acinetobacter baumannii infections: clinical outcome and adverse events.
  Journal
Clin Microbiol Infect 11:682-3 (2005)
DOI:10.1111/j.1469-0691.2005.01198.x
Reference
PMID:16048915 (drug)
  Authors
Kasiakou SK, Michalopoulos A, Soteriades ES, Samonis G, Sermaides GJ, Falagas ME
  Title
Combination therapy with intravenous colistin for management of infections due to multidrug-resistant Gram-negative bacteria in patients without cystic fibrosis.
  Journal
Antimicrob Agents Chemother 49:3136-46 (2005)
DOI:10.1128/AAC.49.8.3136-3146.2005
Reference
  Authors
Doughari HJ, Ndakidemi PA, Human IS, Benade S
  Title
The ecology, biology and pathogenesis of Acinetobacter spp.: an overview.
  Journal
Microbes Environ 26:101-12 (2011)
DOI:10.1264/jsme2.ME10179
Reference
  Authors
Jain R, Danziger LH
  Title
Multidrug-resistant Acinetobacter infections: an emerging challenge to clinicians.
  Journal
Ann Pharmacother 38:1449-59 (2004)
DOI:10.1345/aph.1D592
Reference
  Authors
Gootz TD, Marra A
  Title
Acinetobacter baumannii: an emerging multidrug-resistant threat.
  Journal
Expert Rev Anti Infect Ther 6:309-25 (2008)
DOI:10.1586/14787210.6.3.309
Reference
PMID:16238638 (drug)
  Authors
Hanlon GW
  Title
The emergence of multidrug resistant Acinetobacter species: a major concern in the hospital setting.
  Journal
Lett Appl Microbiol 41:375-8 (2005)
DOI:10.1111/j.1472-765X.2005.01791.x

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