KEGG   DISEASE: Erythema infectiosumHelp
Entry
H00404                      Disease                                

Name
Erythema infectiosum;
Fifth disease
Description
Erythema infectiosum, or fifth disease, is a benign pediatric condition caused by B19 parvovirus. It is a mild, self-limiting 'slapped-cheek' facial rash with low-grade fever and malaise in immunocompetent children. However, B19 parvovirus is associated with a wide clinical spectrum ranging from thrombocytopenia and neurological manifestations in immunocompromised patients and intrauterine fetal death in primary infected pregnant women.
Category
Infectious disease
Brite
Infectious diseases [BR:br08401]
 Viral infections
  Infections caused by ssDNA viruses
   H00404  Erythema infectiosum
Human diseases in ICD-11 classification [BR:br08403]
 01 Certain infectious or parasitic diseases
  Viral infections characterised by skin or mucous membrane lesions
   Varicella zoster virus infections
    1F04  Erythema infectiosum
     H00404  Erythema infectiosum
BRITE hierarchy
Pathogen
Human parvovirus B19 [GN:T40084]
Other DBs
ICD-11: 1F04
ICD-10: B08.3
MeSH: D016731
MedlinePlus: 000977
Reference
PMID:16502203 (description, env_factor, marker)
  Authors
Vafaie J, Schwartz RA
  Title
Erythema infectiosum.
  Journal
J Cutan Med Surg 9:159-61 (2005)
DOI:10.1177/120347540500900401
Reference
  Authors
Broliden K, Tolfvenstam T, Norbeck O
  Title
Clinical aspects of parvovirus B19 infection.
  Journal
J Intern Med 260:285-304 (2006)
DOI:10.1111/j.1365-2796.2006.01697.x
Reference
  Authors
de Jong EP, Walther FJ, Kroes AC, Oepkes D
  Title
Parvovirus B19 infection in pregnancy: new insights and management.
  Journal
Prenat Diagn 31:419-25 (2011)
DOI:10.1002/pd.2714

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