KEGG   DISEASE: Lipoprotein glomerulopathy
Entry
H00887                      Disease                                
Name
Lipoprotein glomerulopathy
Description
Lipoprotein glomerulopathy is a rare hereditary disorder characterized by disturbed remnant lipoprotein catabolism and intravascular glomerular deposition of lipoprotein-containing thrombi. Patients usually present with proteinuria and hypertension, microhematuria is rare, and renal function becomes impaired. Rare mutations in apolipoprotein E (apoE) gene may contribute to the pathogenesis of the disease.
Category
Inherited metabolic disorder
Brite
Human diseases in ICD-11 classification [BR:br08403]
 21 Symptoms, signs or clinical findings, not elsewhere classified
  Symptoms, signs or clinical findings of the genitourinary system
   Clinical findings in specimens from the urinary system
    MF82  Lipoprotein glomerulopathy
     H00887  Lipoprotein glomerulopathy
Gene
APOE [HSA:348] [KO:K04524]
Other DBs
ICD-11: MF82
MeSH: C567089
OMIM: 611771
Reference
PMID:21464714
  Authors
Tsimihodimos V, Elisaf M
  Title
Lipoprotein glomerulopathy.
  Journal
Curr Opin Lipidol 22:262-9 (2011)
DOI:10.1097/MOL.0b013e328345ebb0
Reference
PMID:16490634
  Authors
Sam R, Wu H, Yue L, Mazzone T, Schwartz MM, Arruda JA, Dunea G, Singh AK
  Title
Lipoprotein glomerulopathy: a new apolipoprotein E mutation with enhanced glomerular binding.
  Journal
Am J Kidney Dis 47:539-48 (2006)
DOI:10.1053/j.ajkd.2005.12.031
Reference
PMID:16431249
  Authors
Saito T, Matsunaga A, Oikawa S
  Title
Impact of lipoprotein glomerulopathy on the relationship between lipids and renal diseases.
  Journal
Am J Kidney Dis 47:199-211 (2006)
DOI:10.1053/j.ajkd.2005.10.017

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   OMIM (1)   
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