KEGG   DISEASE: SchistosomiasisHelp
Entry
H01045                      Disease                                

Name
Schistosomiasis
Description
Schistosomiasis is a parasitic disease caused by the genus Schistosoma parasites. Schistosomiasis is the third most devastating tropical disease in the world and WHO estimates 600 million people at risk of infection with 200 million infected. Among nonimmune patients, host's immune response to schistosome eggs leads to acute schistosomiasis that is characterized by cercarial dermatitis and 'Katayama fever'. Life-threatening cardiac and neurological complications may occur. Schistosome eggs can also leads to chronic fibrotic response in host tissues, causing gastrointestinal and liver diseases.
Category
Infectious disease
Brite
Infectious diseases [BR:br08401]
 Parasitic infections
  Infections caused by flat worms
   H01045  Schistosomiasis
Human diseases in ICD-11 classification [BR:br08403]
 01 Certain infectious or parasitic diseases
  Parasitic diseases
   Helminthiases
    Diseases due to trematodes
     1F86  Schistosomiasis
      H01045  Schistosomiasis
BRITE hierarchy
Pathogen
Schistosoma mansoni [GN:smm]
Schistosoma haematobium
Schistosoma japonicum
Drug
Ivermectin [DR:D00804]
Praziquantel [DR:D00471]
Other DBs
ICD-11: 1F86
ICD-10: B65
MeSH: D012552
Reference
PMID:19292768 (description, env_factor, drug)
  Authors
Burke ML, Jones MK, Gobert GN, Li YS, Ellis MK, McManus DP
  Title
Immunopathogenesis of human schistosomiasis.
  Journal
Parasite Immunol 31:163-76 (2009)
DOI:10.1111/j.1365-3024.2009.01098.x
Reference
PMID:17160074 (description, env_factor)
  Authors
Wilson MS, Mentink-Kane MM, Pesce JT, Ramalingam TR, Thompson R, Wynn TA
  Title
Immunopathology of schistosomiasis.
  Journal
Immunol Cell Biol 85:148-54 (2007)
DOI:10.1038/sj.icb.7100014
Reference
PMID:20222897 (description, env_factor, drug)
  Authors
Jaureguiberry S, Paris L, Caumes E
  Title
Acute schistosomiasis, a diagnostic and therapeutic challenge.
  Journal
Clin Microbiol Infect 16:225-31 (2010)
DOI:10.1111/j.1469-0691.2009.03131.x

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