KEGG   DISEASE: Plasminogen deficiency
Entry
H01206                      Disease                                
Name
Plasminogen deficiency
  Subgroup
Ligneous conjunctivitis
Dysplasminogenemia
Description
Plasminogen deficiency is characterized by decreased serum plasminogen activity. Two forms of the disorder are distinguished. Type 1, also called hypoplasminogenemia, is associated with pseudomembrane disease. Ligneous conjunctivitis is the most common of the clinical syndromes associated with plasminogen deficiency, although numerous other organs have been reported to be affected. Type 2, also known as dysplasminogenemia, is characterized by normal, or slightly reduced antigen levels, and absence of clinical manifestations.
Category
Hematologic disease
Brite
Human diseases in ICD-11 classification [BR:br08403]
 03 Diseases of the blood or blood-forming organs
  Coagulation defects, purpura or other haemorrhagic or related conditions
   Fibrinolytic defects
    3B50  Inherited fibrinolytic defects
     H01206  Plasminogen deficiency
Pathway-based classification of diseases [BR:br08402]
 Immune system
  nt06514  Coagulation cascade
   H01206  Plasminogen deficiency
Pathway
hsa04610  Complement and coagulation cascades
Network
nt06514 Coagulation cascade
Gene
PLG [HSA:5340] [KO:K01315]
Drug
Plasminogen [DR:D12149]
Other DBs
ICD-11: 3B50.Y
ICD-10: L90.5
MeSH: C566897
OMIM: 217090
Reference
  Authors
Mehta R, Shapiro AD
  Title
Plasminogen deficiency.
  Journal
Haemophilia 14:1261-8 (2008)
DOI:10.1111/j.1365-2516.2008.01825.x
Reference
  Authors
Schuster V, Hugle B, Tefs K
  Title
Plasminogen deficiency.
  Journal
J Thromb Haemost 5:2315-22 (2007)
DOI:10.1111/j.1538-7836.2007.02776.x

» Japanese version

DBGET integrated database retrieval system