KEGG   DISEASE: Body dysmorphic disorder
Entry
H01447                      Disease                                
Name
Body dysmorphic disorder
Description
Body dysmorphic disorder (BDD) is a psychiatric disorder in which individuals are preoccupied with imagined defects in their appearance, which are not noticeable or appear slight to others. It is characterized by time-consuming behaviors such as mirror gazing, comparing one's appearance with the appearance of others, excessive camouflaging to hide the defect, and seeking reassurance. Patients experience significant distress, disability, and functional impairment, often accompanied by depression and suicidality. There is some clinical and pathologic overlap between obsessive-compulsive disorder (OCD) and BDD such as obsessive thoughts and the performance of ritual behavior. Patients with BDD respond to treatment with serotonergic agents such as clomipramine or selective serotonin reuptake inhibitors (SSRIs), which suggests a dysfunction of central serotonergic neurotransmission as a possible etiological factor. A recent study suggests that cognitive-behavior therapy (CBT) was more effective than treatment with medications.
Category
Mental and behavioural disorder
Brite
Human diseases in ICD-11 classification [BR:br08403]
 06 Mental, behavioural or neurodevelopmental disorders
  Obsessive-compulsive or related disorders
   6B21  Body dysmorphic disorder
    H01447  Body dysmorphic disorder
Comment
In the fifth edition of Diagnostic and Statistical Manual of Mental Disorders (DSM-5), body dysmorphic disorder (BDD) has been subsumed into the obsessive-compulsive disorders and related disorders (OCDRD) category.
Other DBs
ICD-11: 6B21
ICD-10: F45.2
MeSH: D057215
Reference
  Authors
Frias A, Palma C, Farriols N, Gonzalez L
  Title
Comorbidity between obsessive-compulsive disorder and body dysmorphic disorder: prevalence, explanatory theories, and clinical characterization.
  Journal
Neuropsychiatr Dis Treat 11:2233-44 (2015)
DOI:10.2147/NDT.S67636
Reference
  Authors
Pavan C, Simonato P, Marini M, Mazzoleni F, Pavan L, Vindigni V
  Title
Psychopathologic aspects of body dysmorphic disorder: a literature review.
  Journal
Aesthetic Plast Surg 32:473-84 (2008)
DOI:10.1007/s00266-008-9113-2
Reference
  Authors
Li W, Arienzo D, Feusner JD
  Title
Body Dysmorphic Disorder: Neurobiological Features and an Updated Model.
  Journal
Z Klin Psychol Psychother (Gott) 42:184-191 (2013)
DOI:10.1026/1616-3443/a000213
Reference
PMID:11926939 (Drug)
  Authors
Phillips KA, Albertini RS, Rasmussen SA
  Title
A randomized placebo-controlled trial of fluoxetine in body dysmorphic disorder.
  Journal
Arch Gen Psychiatry 59:381-8 (2002)
DOI:10.1001/archpsyc.59.4.381
Reference
  Authors
Hofmann SG, Asnaani A, Vonk IJ, Sawyer AT, Fang A
  Title
The Efficacy of Cognitive Behavioral Therapy: A Review of Meta-analyses.
  Journal
Cognit Ther Res 36:427-440 (2012)
DOI:10.1007/s10608-012-9476-1

» Japanese version

DBGET integrated database retrieval system