KEGG   DISEASE: Bejel
Entry
H01531                      Disease                                

Name
Bejel;
Endemic syphilis
Description
Treponemal infections occurring in humans comprise venereal syphilis and the non-venereal endemic treponematoses. The non-venereal endemic treponematoses are yaws, pinta, and bejel. Bejel, also known as endemic syphilis, is endemic in many parts of the world including Saudi Arabia. The disease usually occurs in patients living in primitive environments with low standard of hygiene. Clinical manifestations of bejel are divided into various stages. Patches on the mucous membranes, angular stomatitis, nonitchy skin eruptions, and generalized lymphadenopathy are the most important early manifestations. In the late stage, affection of skin, bones, and cartilage may lead to severe destruction, especially of the nose and palate.
Category
Infectious disease
Brite
Infectious diseases [BR:br08401]
 Bacterial infections
  Infections caused by spirochaetes
   H01531  Bejel
Human diseases in ICD-11 classification [BR:br08403]
 01 Certain infectious or parasitic diseases
  Other bacterial diseases
   1C1F  Endemic non-venereal syphilis
    H01531  Bejel
Pathogen
Treponema pallidum subsp. endemicum
Drug
Penicillin G benzathine [DR:D02157]
Penicillin G procaine [DR:D02461]
Comment
See also H01318 Yaws and H01530 Pinta.
Other DBs
ICD-11: 1C1F
ICD-10: A65
MeSH: D014211
Reference
  Authors
Engelkens HJ, Vuzevski VD, Stolz E
  Title
Nonvenereal treponematoses in tropical countries.
  Journal
Clin Dermatol 17:143-52; discussion 105-6 (1999)
DOI:10.1016/S0738-081X(99)00007-3
Reference
PMID:2249914
  Authors
Tabbara KF
  Title
Endemic syphilis (Bejel).
  Journal
Int Ophthalmol 14:379-81 (1990)
DOI:10.1007/BF00163561
Reference
PMID:11825779 (pathogen)
  Authors
Antal GM, Lukehart SA, Meheus AZ
  Title
The endemic treponematoses.
  Journal
Microbes Infect 4:83-94 (2002)
DOI:10.1016/S1286-4579(01)01513-1

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