Chronic arterial occlusive disease

Arteriosclerosis obliterans [DS:H01626]
Buerger disease [DS:H01625]

Chronic arterial occlusive disease is a highly prevalent peripheral vascular disorder. This disease is caused by arteriosclerosis obliterans (ASO), thromboangiitis obliterans (Buerger's disease), primary arterial thrombosis, embolism and so on. Of these, ASO is the most frequently encountered. Although differing clinically and pathologically, these diseases are similar in that they cause ischemia of tissues. The symptoms of chronic occlusive arterial disease result from impairment of blood flow to the extremities. Intermittent claudication is the commonest and usually the earliest symptom.

Vascular disease

Pentoxifylline [DR:D00501]

See also H01625 Buerger's disease and H01626 Arteriosclerosis obliterans.

PMID:14042045

JUERGENS JL

Chronic occlusive arterial disease of the extremities.

Circulation 27:964-9 (1963)
DOI:10.1161/01.CIR.27.5.964

PMID:21115876

Idei N, Nishioka K, Soga J, Hidaka T, Hata T, Fujii Y, Fujimura N, Maruhashi T, Mikami S, Teragawa H, Kihara Y, Noma K, Chayama K, Higashi Y

Vascular function and circulating progenitor cells in thromboangitis obliterans (Buerger's disease) and atherosclerosis obliterans.

Hypertension 57:70-8 (2011)
DOI:10.1161/HYPERTENSIONAHA.110.163683

PMID:10908215 (drug)

Lievre M, Morand S, Besse B, Fiessinger JN, Boissel JP

Oral Beraprost sodium, a prostaglandin I(2) analogue, for intermittent claudication: a double-blind, randomized, multicenter controlled trial. Beraprost et Claudication Intermittente (BERCI) Research Group.

Circulation 102:426-31 (2000)
DOI:10.1161/01.CIR.102.4.426