KEGG   DISEASE: Panic disorderHelp
Entry
H01664                      Disease                                

Name
Panic disorder
Description
Panic disorder (PD) is a common type of anxiety disorder, characterized by unexpected and repeated panic attacks or fear of future panic attacks. It has a rapid onset and includes symptoms such as palpitations, chest pain, sweating and shaking. Some physical illnesses (e.g. asthma) commonly occur with panic disorder, and certain lifestyle factors (e.g. smoking) increase the risk for the disorder, but causal pathways are still unclear. In recent years, an association was found between panic symptoms and increased activity in the right frontal region of the brain. Genetic susceptibility factors also exist, but their exact nature and pathophysiological mechanisms remain unknown. Cognitive behavioural therapy (CBT) and several medications, including selective serotonin reuptake inhibitors (SSRIs), serotonin-norepinephrine reuptake inhibitors (SNRIs), tricyclic antidepressants (TCAs) and benzodiazepines are effective for PD. Among these, SSRIs and SNRIs are considered to be first-line treatment agents because of their efficacy and favorable side effect profile.
Category
Mental and behavioural disorder
Brite
Human diseases [BR:br08402]
 Other diseases
  Mental and behavioural disorders
   H01664  Panic disorder
Human diseases in ICD-11 classification [BR:br08403]
 06 Mental, behavioural or neurodevelopmental disorders
  Anxiety or fear-related disorders
   6B01  Panic disorder
    H01664  Panic disorder
BRITE hierarchy
Env factor
Nicotine [CPD:C00745]
Caffeine [CPD:C07481]
Drug
Clonazepam [DR:D00280]
Alprazolam [DR:D00225]
Fluoxetine hydrochloride [DR:D00823]
Paroxetine hydrochloride hydrate [DR:D02260]
Paroxetine hydrochloride [DR:D05374]
Paroxetine mesylate [DR:D05375]
Sertraline hydrochloride [DR:D00825]
Venlafaxine hydrochloride [DR:D00821]
Other DBs
ICD-11: 6B01
ICD-10: F41.0
MeSH: D016584
OMIM: 167870
Reference
  Authors
Roy-Byrne PP, Craske MG, Stein MB
  Title
Panic disorder.
  Journal
Lancet 368:1023-32 (2006)
DOI:10.1016/S0140-6736(06)69418-X
Reference
  Authors
Li H, Wang J, Li C, Xiao Z
  Title
Repetitive transcranial magnetic stimulation (rTMS) for panic disorder in adults.
  Journal
Cochrane Database Syst Rev CD009083 (2014)
DOI:10.1002/14651858.CD009083.pub2
Reference
PMID:27089322 (drug)
  Authors
Giampaolo P, Alessandra A, Raffaele B, Elisa M, Giuseppina D, Paolo C, Maria N, Daniela C
  Title
Is There Room for Second-Generation Antipsychotics in the Pharmacotherapy of Panic Disorder? A Systematic Review Based on PRISMA Guidelines.
  Journal
Int J Mol Sci 17:551 (2016)
DOI:10.3390/ijms17040551

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