KEGG   DISEASE: 黄色腫
エントリ  
H01661                                                             

名称    
黄色腫
  下位グループ
脳腱黄色腫症 [DS:H00151]
概要    
Xanthomas are benign and usually yellow plaques, papules, or nodules that develop in the cutis and subcutaneous tissue. They evolve as clusters of foam cells and favor the neck, upper trunk, flexural folds and periorbital region. The foam cells are formed from macrophages as a consequence of gradual intracellular accumulation of lipids taken up by specific receptors or by the mechanism of phagocytosis. They are seen in several lipidoses and are usually indicative of a derangement in lipoprotein metabolism, in particular familial hypercholesterolemia. Prevention of xanthomas goes hand in hand with the management of the underlying disorders of lipid metabolism. Normolipemic xanthomatosis may be seen in several rare conditions.
カテゴリ  
皮膚疾患; 先天性代謝異常症
階層分類  
ヒト疾患 [BR:jp08402]
 皮膚疾患
  皮膚と軟部組織の疾患
   H01661  黄色腫
 先天性代謝異常症
  先天性脂質・糖脂質代謝異常症
   H01661  黄色腫
ICD-11 による疾患分類 [BR:jp08403]
 14 皮膚の疾患
  皮膚に影響する代謝性及び栄養性疾患
   EB90  代謝経路の乱れの結果による皮膚症
    H01661  黄色腫
治療薬   
プロブコール [DR:D00476]
リンク   
ICD-11: EB90.2
ICD-10: E75.5 E78
MeSH: D014973
OMIM: 602247
文献    
  著者
Zak A, Zeman M, Slaby A, Vecka M
  タイトル
Xanthomas: clinical and pathophysiological relations.
  雑誌
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 158:181-8 (2014)
DOI:10.5507/bp.2014.016
文献    
  著者
Babu R, Venkataram A, Santhosh S, Shivaswamy S
  タイトル
Giant Tuberous Xanthomas in a Case of Type IIA Hypercholesterolemia.
  雑誌
J Cutan Aesthet Surg 5:204-6 (2012)
DOI:10.4103/0974-2077.101384
文献    
PMID:23741215 (drug)
  著者
Miyagawa F, Fukumoto T, Kobayashi N, Asada H
  タイトル
Successful treatment of diffuse normolipemic plane xanthoma with probucol.
  雑誌
Case Rep Dermatol 5:148-51 (2013)
DOI:10.1159/000351682
文献    
  著者
Pietroleonardo L, Ruzicka T
  タイトル
Skin manifestations in familial heterozygous hypercholesterolemia.
  雑誌
Acta Dermatovenerol Alp Pannonica Adriat 18:183-7 (2009)

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