KEGG   Dinoroseobacter shibae: Dshi_2419
Entry
Dshi_2419         CDS       T00612                                 
Symbol
ddl
Name
(GenBank) D-alanine--D-alanine ligase
  KO
K01921  D-alanine-D-alanine ligase [EC:6.3.2.4]
Organism
dsh  Dinoroseobacter shibae
Pathway
dsh00470  D-Amino acid metabolism
dsh00550  Peptidoglycan biosynthesis
dsh01100  Metabolic pathways
dsh01502  Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:dsh00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00470 D-Amino acid metabolism
    Dshi_2419 (ddl)
  09107 Glycan biosynthesis and metabolism
   00550 Peptidoglycan biosynthesis
    Dshi_2419 (ddl)
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01502 Vancomycin resistance
    Dshi_2419 (ddl)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01011 Peptidoglycan biosynthesis and degradation proteins [BR:dsh01011]
    Dshi_2419 (ddl)
Enzymes [BR:dsh01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.4  D-alanine---D-alanine ligase
     Dshi_2419 (ddl)
Peptidoglycan biosynthesis and degradation proteins [BR:dsh01011]
 Precursor biosynthesis
  Amino acid ligase
   Dshi_2419 (ddl)
SSDB
Motif
Pfam: Dala_Dala_lig_C Dala_Dala_lig_N B12-binding ATP-grasp_4
Other DBs
NCBI-ProteinID: ABV94153
RoseoBase: Dshi_2419
UniProt: A8LS60
Position
complement(2559329..2560255)
AA seq 308 aa
MRRDVSSKASPKVAMMMGGTSSERAVSLSSGRECGAALRAEGFEVIDLDAGPDLAARLED
LRPDVVFNALHGRWGEDGCVQGLLEWLRIPYTHSGVLASALAMDKERTKAAYAAAGLPIA
TSGLFTRAQIAARHVMPPPYVIKPYNEGSSVGVYLVPEGAEAAPELADDLPDTLMVEAFV
PGRELTVTVQGDRALCVTDIVTEGWYDYDAKYVPGGSRHVLPAEVPGDVYDACMAHAETA
HRVLGCRGISRTDFRWDPRRSLDGLALLETNTQPGMTPTSLTPEQAQHVGLGFGALCRWI
VEDASCDR
NT seq 927 nt   +upstreamnt  +downstreamnt
atgaggcgggacgtgtcgagcaaggcatcccccaaggtggccatgatgatgggcggtacc
tcgtcggaacgcgccgtgtccctgtcgtcgggacgcgaatgcggggctgcgctccgggca
gaggggttcgaggtgatcgacctcgatgcgggtccggacctggccgcgcggctcgaagat
ctgcgcccggacgtggtgttcaacgcgctccatggccgctggggggaggatggctgcgtg
cagggcctgctggaatggctgcgcatcccctatacccattcgggcgtgctggcctcggcc
ctggcgatggacaaggaacgcaccaaggccgcctatgcggcggccgggctgccgatcgcc
acgagcgggcttttcaccagggcgcagatcgccgcgcgccacgtgatgccgccgccttac
gtgatcaaaccctataatgagggctcgtccgtcggggtgtacctggtgcccgagggggcg
gaggccgcgccggagctggcggacgacctgcccgacacgctgatggtggaggccttcgtg
cccgggcgggagctgaccgtgaccgtgcagggggaccgcgcgctctgtgtcaccgatatc
gtgaccgagggctggtacgattacgacgcgaaatacgtccccggcgggtcgcgccatgta
ttgccggccgaggtgcccggggatgtctacgacgcctgcatggcccatgccgagaccgcg
caccgggtactcggctgccgcgggatctcgcgcaccgatttccgctgggatccgcgccgc
agcctcgatgggctggccctgctggagaccaacacccagccggggatgacgcccacctcc
ctgacccccgaacaggcgcagcatgtggggctgggcttcggcgcgctctgccgctggatc
gtggaggacgcctcatgcgaccgttga

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