KEGG   PATHWAY: dye01230Help
dye01230                    Pathway                                

Biosynthesis of amino acids - Dyella sp. M7H15-1
This map presents a modular architecture of the biosynthesis pathways of twenty amino acids, which may be viewed as consisting of the core part and its extensions. The core part is the KEGG module for conversion of three-carbon compounds from glyceraldehyde-3P to pyruvate [MD:M00002], together with the pathways around serine and glycine. This KEGG module is the most conserved one in the KEGG MODULE database and is found in almost all the completely sequenced genomes. The extensions are the pathways containing the reaction modules RM001, RM033, RM032, and RM002 for biosynthesis of branched-chain amino acids (left) and basic amino acids (bottom), and the pathways for biosynthesis of histidine and aromatic amino acids (top right). It is interesting to note that the so-called essential amino acids that cannot be synthesized in human and other organisms generally appear in these extensions. Furthermore, the bottom extension of basic amino acids appears to be most divergent containing multiple pathways for lysine biosynthesis and multiple gene sets for arginine biosynthesis.
BRITE hierarchy
Pathway map
dye01230  Biosynthesis of amino acids

Ortholog table
dye_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:dye01230]
dye_M00007  Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH:dye01230]
dye_M00010  Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH:dye01230]
dye_M00016  Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine [PATH:dye01230]
dye_M00018  Threonine biosynthesis, aspartate => homoserine => threonine [PATH:dye01230]
dye_M00022  Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate [PATH:dye01230]
dye_M00023  Tryptophan biosynthesis, chorismate => tryptophan [PATH:dye01230]
dye_M00024  Phenylalanine biosynthesis, chorismate => phenylalanine [PATH:dye01230]
dye_M00026  Histidine biosynthesis, PRPP => histidine [PATH:dye01230]
dye_M00028  Ornithine biosynthesis, glutamate => ornithine [PATH:dye01230]
dye_M00338  Cysteine biosynthesis, homocysteine + serine => cysteine [PATH:dye01230]
dye_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:dye01230]
dye_M00845  Arginine biosynthesis, glutamate => acetylcitrulline => arginine [PATH:dye01230]
Dyella sp. M7H15-1 [GN:dye]
KO pathway

DBGET integrated database retrieval system