KEGG   Equus asinus (ass): 106841344
Entry
106841344         CDS       T04645                                 
Symbol
PLA2G4E
Name
(RefSeq) cytosolic phospholipase A2 epsilon
  KO
K16342  cytosolic phospholipase A2 [EC:3.1.1.4]
Organism
eai  Equus asinus (ass)
Pathway
eai00564  Glycerophospholipid metabolism
eai00565  Ether lipid metabolism
eai00590  Arachidonic acid metabolism
eai00591  Linoleic acid metabolism
eai00592  alpha-Linolenic acid metabolism
eai01100  Metabolic pathways
eai04010  MAPK signaling pathway
eai04014  Ras signaling pathway
eai04072  Phospholipase D signaling pathway
eai04217  Necroptosis
eai04270  Vascular smooth muscle contraction
eai04370  VEGF signaling pathway
eai04611  Platelet activation
eai04664  Fc epsilon RI signaling pathway
eai04666  Fc gamma R-mediated phagocytosis
eai04724  Glutamatergic synapse
eai04726  Serotonergic synapse
eai04730  Long-term depression
eai04750  Inflammatory mediator regulation of TRP channels
eai04912  GnRH signaling pathway
eai04913  Ovarian steroidogenesis
eai04921  Oxytocin signaling pathway
eai05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:eai00001]
 09100 Metabolism
  09103 Lipid metabolism
   00564 Glycerophospholipid metabolism
    106841344 (PLA2G4E)
   00565 Ether lipid metabolism
    106841344 (PLA2G4E)
   00590 Arachidonic acid metabolism
    106841344 (PLA2G4E)
   00591 Linoleic acid metabolism
    106841344 (PLA2G4E)
   00592 alpha-Linolenic acid metabolism
    106841344 (PLA2G4E)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    106841344 (PLA2G4E)
   04014 Ras signaling pathway
    106841344 (PLA2G4E)
   04370 VEGF signaling pathway
    106841344 (PLA2G4E)
   04072 Phospholipase D signaling pathway
    106841344 (PLA2G4E)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    106841344 (PLA2G4E)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    106841344 (PLA2G4E)
   04664 Fc epsilon RI signaling pathway
    106841344 (PLA2G4E)
   04666 Fc gamma R-mediated phagocytosis
    106841344 (PLA2G4E)
  09152 Endocrine system
   04912 GnRH signaling pathway
    106841344 (PLA2G4E)
   04913 Ovarian steroidogenesis
    106841344 (PLA2G4E)
   04921 Oxytocin signaling pathway
    106841344 (PLA2G4E)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    106841344 (PLA2G4E)
  09156 Nervous system
   04724 Glutamatergic synapse
    106841344 (PLA2G4E)
   04726 Serotonergic synapse
    106841344 (PLA2G4E)
   04730 Long-term depression
    106841344 (PLA2G4E)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    106841344 (PLA2G4E)
 09160 Human Diseases
  09161 Cancer: overview
   05231 Choline metabolism in cancer
    106841344 (PLA2G4E)
Enzymes [BR:eai01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.1  Carboxylic-ester hydrolases
    3.1.1.4  phospholipase A2
     106841344 (PLA2G4E)
SSDB
Motif
Pfam: cPLA2_C2 PLA2_B C2
Other DBs
NCBI-GeneID: 106841344
NCBI-ProteinID: XP_044621031
Position
2:191518984..191553678
AA seq 835 aa
MLQRQMPAWVFHSLPDPSQTEDGRPSATCTLERGLFPCHLLTVRVIQMKNVRQADVVSQT
DCFVSLWLPTASHERLRTRTISNCPNPEWNETFTFQIQSQVKNVLELSVCDEDTVTPDDH
LLTVLYDLTKLCFRKKTHVKFPLNPEGMEELEVEFLLEKSPDPPETLITNGVLVSRQVSC
LEVHAESRRRRKCGKQKDLLVTVTESFEHTQRISHCLEPCCPNPACFHYPKYFQSQIHVE
GPKSPWSCGLCCCCAHKKTGPICQPLDCLPDGQTVTLPVGENCELHMKSTPCPQTLDVRL
GFSLCSAELEFLQKRRLVVAEALKQVLQLEEDLQEDEVPLIAIMATGGGTRSMTAMYGHL
LGLQKLNILNCASYITGLSGATWTMATLYRDPDWSSKNLEPAIFEARRHVVKDKLPALFP
DQLSKFQEELRQRSQEGYKVTFTDFWGLLIEACLGDERNECKLSDQRAALCQGQNPLPIY
LTINVKDDVSNQDFREWCEFSPYEVGLQKYGAFIPTELFGSEFFMGRLMKRIPESRMCYM
LGLWSSIFSLNLLDAWNLSHTSEEFFYRWTRERVHDIEDEPLLPEIPKCDENILDTTVVI
PGSWLSNTFRSILTHRPFVSEFHNFLRGLQLHTDYLQNTEFSRWKDTVLDGFPNQLTASV
NHLCLLDTAFFVNSSYPPLLRPERKVDLIIHLNYCAGSQTKPMKQTCEYCTVQNIPFPKY
ELQEEEEKLKECYLMENLQEPDVPVVIFFPLINDTFQKYKAPGVERNPEELEQGQVDIYG
PKTPYATKELTYTEAAFDKLVKLSEYNILNNKDKLLQALRLAVEKKRCLKSQCPS
NT seq 2508 nt   +upstreamnt  +downstreamnt
atgctccagaggcagatgcccgcctgggtcttccactccctgccagacccaagccaaaca
gaagatggcaggccgtcggccacctgcaccttggagagggggctgtttccatgccacctg
ctgacagtgagggtcatccagatgaaaaacgtgcgacaggctgatgtggtgagccagaca
gactgctttgtgagcctctggctgcccaccgcctctcatgagaggctgaggactaggacc
atctccaactgccccaacccagagtggaatgaaaccttcaccttccagatccagagccaa
gtgaagaacgtgctagagctgagcgtctgcgatgaagacacagtgacaccagatgaccat
ctcttgacagttctctatgacctcaccaagctctgcttccgaaagaaaacccacgtgaag
ttcccactcaacccagagggcatggaggagctagaggtggagttcctgctggagaaaagt
cctgatccacctgagaccctcatcaccaatggcgtgctggtgtctcgacaggtctcctgc
ctggaggtgcatgcagaatccaggaggcggagaaagtgtggcaaacagaaggacctcctg
gtgacagtgacggagtcctttgagcacacccagcgcatctcgcactgcctggagccctgc
tgcccaaaccctgcctgcttccactaccccaagtacttccagtcccagattcacgtggag
gggcccaagagtccatggagctgtgggctttgctgctgctgtgcgcacaagaaaaccggc
cccatctgccagcccctcgactgcctccccgacggccagacggtgaccctgcctgtgggc
gagaactgtgaactacacatgaagtccacaccctgcccccagacgctggacgtgcggctg
ggcttcagcctgtgctcggcagagctggagttcctgcagaagcggaggctggtggtggct
gaggcgctgaagcaggtgttgcagctggaggaggacctgcaggaggacgaggtaccactg
atagccatcatggccaccgggggtggaacaaggtccatgacggccatgtacggccacctg
ctgggactgcagaagctgaacatcctgaactgtgccagctacatcactggcttgtcaggg
gccacctggaccatggctaccttgtaccgtgacccagactggtcctccaaaaacctggag
cctgccatctttgaggcacggaggcacgtggtcaaggacaagttgcctgccctgttccca
gaccagctctccaaattccaggaggagctccggcagcgcagccaggaagggtacaaggtc
acctttacagacttctggggcttgctgatcgaggcctgtctgggggacgagagaaatgaa
tgcaaactgtcagaccagcgtgctgctttgtgccagggccagaaccccctgcccatctac
ctcaccatcaatgtcaaggatgatgtaagcaaccaggatttcagagagtggtgcgagttc
tccccctacgaggtgggcctgcagaaatacggggccttcatccccaccgagctctttggc
tccgagttcttcatgggacggctgatgaagaggatcccagagtcgcggatgtgctacatg
ctaggtttgtggagcagcatcttctccctgaacctgcttgatgcctggaatctgtcccac
acctcggaggagtttttctacaggtggacaagggagagagtgcatgacatcgaagacgag
ccactcctgcctgaaatccccaaatgtgatgaaaacatcctggacaccacggtggtgatc
ccagggtcgtggctgtccaacacattccgcagcatcctcacccatcggcccttcgtgtct
gagttccacaacttcctgcgggggctgcagctgcacaccgactacctccagaacacagag
ttctccaggtggaaagacaccgtgctggatggtttcccaaaccagctgacggcgtctgtg
aaccacctgtgcctgctggacaccgcgttcttcgtcaactccagctacccgcccctcctc
cggcctgagagaaaagtcgacctcatcatccatctcaactactgtgccggatcccagaca
aagcccatgaagcagacctgtgagtactgcaccgtgcagaacatccccttccccaagtac
gagctgcaggaggaggaggagaagctcaaggagtgctaccttatggagaacctgcaggaa
cctgatgtccccgtcgtgattttcttccctctcatcaacgacaccttccagaagtacaag
gccccaggtgtggagcgaaaccccgaggagctggagcagggccaggtcgacatttatggc
cccaaaactccctacgccaccaaggagctgacgtacacagaggccgccttcgacaagctg
gtgaagctctccgagtacaacatcctgaataacaaggacaagctccttcaggccttgcgg
ctggcagtggagaagaagagatgcctgaagagccagtgtccctcctaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (23)   
   KEGG PATHWAY (23)   
Chemical substance (14)   
   KEGG COMPOUND (14)   
Chemical reaction (8)   
   KEGG ENZYME (1)   
   KEGG REACTION (7)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (3)   
   Pfam (3)   
All databases (57)   

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