KEGG   Equus asinus (ass): 106841512
Entry
106841512         CDS       T04645                                 
Symbol
TYK2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2 isoform X2
  KO
K11219  non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]
Organism
eai  Equus asinus (ass)
Pathway
eai04217  Necroptosis
eai04380  Osteoclast differentiation
eai04620  Toll-like receptor signaling pathway
eai04621  NOD-like receptor signaling pathway
eai04630  JAK-STAT signaling pathway
eai04658  Th1 and Th2 cell differentiation
eai04659  Th17 cell differentiation
eai05145  Toxoplasmosis
eai05160  Hepatitis C
eai05161  Hepatitis B
eai05162  Measles
eai05164  Influenza A
eai05165  Human papillomavirus infection
eai05167  Kaposi sarcoma-associated herpesvirus infection
eai05168  Herpes simplex virus 1 infection
eai05169  Epstein-Barr virus infection
eai05171  Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:eai00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    106841512 (TYK2)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    106841512 (TYK2)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    106841512 (TYK2)
   04621 NOD-like receptor signaling pathway
    106841512 (TYK2)
   04658 Th1 and Th2 cell differentiation
    106841512 (TYK2)
   04659 Th17 cell differentiation
    106841512 (TYK2)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    106841512 (TYK2)
 09160 Human Diseases
  09172 Infectious disease: viral
   05161 Hepatitis B
    106841512 (TYK2)
   05160 Hepatitis C
    106841512 (TYK2)
   05171 Coronavirus disease - COVID-19
    106841512 (TYK2)
   05164 Influenza A
    106841512 (TYK2)
   05162 Measles
    106841512 (TYK2)
   05168 Herpes simplex virus 1 infection
    106841512 (TYK2)
   05167 Kaposi sarcoma-associated herpesvirus infection
    106841512 (TYK2)
   05169 Epstein-Barr virus infection
    106841512 (TYK2)
   05165 Human papillomavirus infection
    106841512 (TYK2)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    106841512 (TYK2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:eai01001]
    106841512 (TYK2)
Enzymes [BR:eai01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     106841512 (TYK2)
Protein kinases [BR:eai01001]
 Non-receptor tyrosine kinases
  JAK family [OT]
   106841512 (TYK2)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase Jak1_Phl FERM_F2 FERM_F1 Kdo Kinase-like FERM_C_FAK1 ABC1 RIO1
Other DBs
NCBI-GeneID: 106841512
NCBI-ProteinID: XP_014713051
Position
20:complement(8907911..8925268)
AA seq 1184 aa
MPLCHWGATARGSEPHGDGAQAMATRGGLKVLLHWAGPGGGEPWVTFSEGTLTAEEVCIH
VAHKVGITPPCFNLFALFDAQAQVWLPPNHILEVSGDTSLTLHFRMRFYFRNWHGMNPQE
PAVYRCGPPGAEAHSGQAEQGMQLLDSASFEYLFEQGKHEFVNDVASLWELSSEEEIHHF
KNESLGMAFLHLCHLALCRGVPVEKVAKKISFQDCIPRSFRRQIRQHSALTRLRLRSIFR
RFLRAFQPGRLCQQVVMVKYLATLERLAPRFGSERVPVCHLALLAQAEGDSYYIGDSGHA
PPDPGPEAAAGPPTHEVLVTGTGGIQWRPVQAEGPSGSGGDSNRNPGAGPSGKKAKAQEV
GDQPVDRPREVPWTYFCDFQDITHVVLKERHVSIHCQDNRCLELTLPSRALALSLVSLVD
GYFRLTADSSHYLCHQVAPPRLVMSIQDGIHGPLLEPFVLAKLQPEEGLYLIHWSTSHLN
RLILTVAQRDQSPGMKALHLRKFPIELRAGAFELEGWGRTFPSVRELRAALHGCSLQAGA
DHFALRRCCLPRPGEISNLIIMRGPRASPRLLNLSQLSFYRICQDDITQLSHLGQGTRTN
VYEGLLRVQGGGPEEDKADDGDPPMPGGGRGQELRVVLKVLDSSHHDIALAFYETASLMS
QVSHVHLAFVHGLCVHGSENIMVTEHVEHGPLDVWLRRERGHVPMAWKVAVAQQLAGALS
YLEDKSLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWMAPEC
LSGGANSLSTAADKWGFGATLLEICFDGEAPLQARSPFEKEHFYHMQHRLPEPSCPELAV
LTSQCLTYEPAQRPSFRTVLRDLTRLQPQNLVDVLAVNLDSLASDPTVFHKRYLKKIRDL
GEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQLRTGWRREIDILRTLYHEHIVKYK
GCCEDQGEKSVQLVMEYMPLGSLRDYLPRHNVGLGQLLLFAQQICEGMAYLHAQHYVHRD
LAARNVLLDHDKLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYALECLKESKFYYASD
VWSFGVTMYELLTYCDSSQSPPSKFIELIGLTQGQMTVLRLTELLERGERLPRPEKCPCE
IYLLMKNCWEAEASFRPTFQNLIPVLKTVHEKYQGRAPSVFSVC
NT seq 3555 nt   +upstreamnt  +downstreamnt
atgcctctgtgccactggggggccaccgccaggggcagcgagccccatggggatggagct
caggctatggccaccaggggaggcctgaaggtacttctgcactgggctggccccggcggc
ggggagccctgggtcaccttcagcgagggcacactgaccgcggaggaggtctgcatccac
gttgctcacaaagtcggcatcaccccaccatgcttcaacctcttcgccctctttgatgcc
caggcccaggtctggctgcctccgaaccacatcctggaggtctctggagacacaagcctg
actctgcacttccgcatgaggttttacttccggaactggcatggcatgaatccgcaggag
ccagccgtgtaccgctgcgggcccccgggggccgaggctcactccggacaggcagagcag
ggcatgcagctcctggactcagcttcctttgagtacctcttcgagcagggcaagcacgag
tttgtgaacgatgtggcatcgctgtgggagctgtcgagtgaggaggagatccaccacttt
aagaacgaaagcctgggcatggccttcctgcacctctgccacctcgctctctgccgcggt
gtccccgtggagaaggtggccaagaagatcagcttccaggactgcatcccgcgctccttc
cgccgccagatccgccagcacagcgcgctcacgcgcctgcgcctgcgcagcatcttccgc
cgcttcctgcgggccttccagccgggccgcctgtgccagcaggtcgtcatggtcaagtac
ctggccacgctcgagcgcctggcgccccgcttcggctcggagcgcgtgcccgtgtgccac
ctggcgctgctggcccaggccgagggggactcctactacatcggggacagcgggcacgcc
cccccggaccccgggcccgaggctgctgcgggaccccctacccacgaggtgctagtgaca
ggcaccggtggcatccagtggcggccggtgcaggcagagggtcccagtggcagtggcggt
gacagcaacaggaatcctggtgctggcccatccgggaagaaagccaaggcccaagaggtg
ggcgaccagccagtggacaggccgcgggaggtgccgtggacctacttctgtgacttccag
gacatcacccatgtggtgctcaaagaacgccacgtcagcatccactgtcaggacaacaga
tgcctggagctgacgctgccttcccgggccttggccctgtccttggtgtcgctggtggat
ggctatttccgcctgacagccgactcgagccactacctgtgccaccaggtggcccctcca
cggctggtgatgagcatccaggacggtatccacggccctctgctggagccatttgtgctg
gccaagctgcagccagaggagggcctctacctcatccactggagcaccagccacctcaac
cgcctcatcctcacggtggcccagcgcgaccagtcgcccggcatgaaggccctgcacctg
cgcaagttccccatcgagctgcgggccggggccttcgagctggagggctggggccgcacc
ttccccagcgtgcgcgagctgcgggccgcgctgcacggctgctccctgcaggccggcgcc
gaccacttcgctctgcgccgctgctgcctcccacggccaggagagatctccaacctcatc
atcatgcgggggcctcgggccagcccccggctgctcaacctcagccagctcagcttctac
cgcatctgccaggacgacatcacccagctgtcacacctgggccagggcacaaggaccaac
gtgtacgagggcctcttgcgagtgcagggcggaggccccgaggaggacaaggcagacgac
ggggacccccccatgcccggcgggggtcgcgggcaggagctgcgagtggtcctcaaggtg
ctagactccagtcaccatgacatcgccctggccttctacgagacggccagcctcatgagc
caggtctcccacgtgcacctggccttcgtgcatgggctctgcgtgcacggctccgagaac
atcatggtgacggagcacgtggagcacgggccgctggacgtgtggctgcggcgggagagg
ggccacgtgcccatggcctggaaggtggccgtggcccagcagctggccggcgccctcagc
tacctggaagacaagagcctggttcacggtaacgtgtgtggccggaacatcttgctggcc
cggctggggctggcggagggcaccagccccttcatcaagctgagtgaccccggcgtgggc
ctgggcgccctatccagggaggagcgggtggagcggatcccctggatggcccccgagtgc
ctatcgggtggggccaatagcctaagcacagcagctgacaaatggggctttggtgccacc
ctcctggagatctgcttcgacggggaggcccccctgcaggcccgcagccccttcgagaaa
gagcacttctaccacatgcaacaccggctgcctgagccctcctgcccggagctggccgtg
ctcaccagccagtgcctgacctacgagccagcgcagcggccgtccttccgcaccgtcctg
cgtgacctcactcggctgcaaccccaaaatcttgttgacgtcttggctgtgaacctggac
tcgctggcgtctgaccccactgttttccacaagcgctatttgaaaaagatccgggatctg
ggcgagggtcacttcggcaaggtcagcctgtactgctacgacccgaccaacgacggcact
ggagagatggtggccgtgaaggccctcaaggccgactgcggcccccagctccgcaccggc
tggcggcgggagatcgacatcctgcgtacgctctaccacgagcacatcgtcaagtacaag
ggctgctgcgaggaccaaggcgagaagtcggtgcagctcgtcatggagtacatgcccttg
ggcagcctccgagactacctgccacggcacaacgtcgggctgggccagctgctgctcttc
gcccagcagatctgcgagggcatggcctacctgcacgcgcagcactacgtgcaccgagac
ctggccgcgcgcaacgtgctgctggaccatgacaagctggtcaagatcggggactttggc
ttagccaaggccgtacccgaaggccacgagtactaccgcgtgcgagaggatggggacagc
ccggtgttctggtatgccttggagtgcctgaaggagtctaagttctactatgcgtccgac
gtctggtcctttggggtcaccatgtatgagctgctgacttactgtgactccagccagagc
ccgccctcgaaattcatcgagctcataggcctcacccaggggcagatgactgtgctgcgg
ctcacggagctgctggaacgaggggagaggctgccgcggcccgagaagtgtccctgtgag
atctatctccttatgaagaactgctgggaggcagaggcctccttccgcccgaccttccag
aacctcatacccgtcctcaaaacggtgcacgagaaataccaaggccgggcgccctcggtg
ttcagcgtgtgctga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (17)   
   KEGG PATHWAY (17)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (4)   
   RefSeq(pep) (4)   
DNA sequence (11)   
   RefSeq(nuc) (11)   
Protein domain (10)   
   Pfam (10)   
All databases (51)   

Download RDF
DBGET integrated database retrieval system