KEGG   Equus asinus (ass): 106842382
Entry
106842382         CDS       T04645                                 
Symbol
ARHGEF12
Name
(RefSeq) rho guanine nucleotide exchange factor 12 isoform X1
  KO
K07532  Rho guanine nucleotide exchange factor 12
Organism
eai  Equus asinus (ass)
Pathway
eai04270  Vascular smooth muscle contraction
eai04360  Axon guidance
eai04611  Platelet activation
eai04625  C-type lectin receptor signaling pathway
eai04810  Regulation of actin cytoskeleton
eai05135  Yersinia infection
eai05152  Tuberculosis
eai05163  Human cytomegalovirus infection
eai05200  Pathways in cancer
eai05205  Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:eai00001]
 09140 Cellular Processes
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    106842382 (ARHGEF12)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    106842382 (ARHGEF12)
   04625 C-type lectin receptor signaling pathway
    106842382 (ARHGEF12)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    106842382 (ARHGEF12)
  09158 Development and regeneration
   04360 Axon guidance
    106842382 (ARHGEF12)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    106842382 (ARHGEF12)
   05205 Proteoglycans in cancer
    106842382 (ARHGEF12)
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    106842382 (ARHGEF12)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    106842382 (ARHGEF12)
   05152 Tuberculosis
    106842382 (ARHGEF12)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:eai04131]
    106842382 (ARHGEF12)
Membrane trafficking [BR:eai04131]
 Others
  Rho GTPase associated proteins
   Rho guanine nucleotide exchange factors (GEFs)
    106842382 (ARHGEF12)
SSDB
Motif
Pfam: RGS-like PH_16 RhoGEF PDZ PDZ_6 PH_13 PDZ_2 Tricorn_PDZ AAA_23
Other DBs
NCBI-GeneID: 106842382
NCBI-ProteinID: XP_044607600
Position
20:complement(31137941..31278147)
AA seq 1544 aa
MSGTQSTITDRFPLKKPIRHGSILNRESPTDKKQKVERSASHDFDPTDSSSKKTKSSSEE
SRSEIYGLVQRCVIIQKDDNGFGLTVSGDNPVFVQSVKEDGAAMRAGVQTGDRIIKVNGT
LVTHSNHLEVVKLIKSGSYVALTVQGRPPGSPQIPLADSEVEPSVIGHMSPIMTSPHSPG
ASGNMERITSPVLMGEENNVVHNQKVEILRKMLQKEQERLQLLQEDYNRTPAQRLLKEIQ
EAKKHIPQLQEQLSKATGSAQDGAVVASSKSLGDALTVSEVEADPGDGLGRIDYSSGDVS
RHSSDNADSPKSGLKERIYLEENPEKSEVNQDIDTQSLIGSPSTRIAPHIIGAEDDDFGT
EHEQINGQCSCFQSIELLKSRPAHLAVFLHHVVSQFDPATLLCYLYSDLYKQTNSKETRR
VFLEFHQFFLDRSAHLKVSVPDEISVDLDKRRPELIPEDLHRHYIQTMQEKVHPEVQRHL
EDFRQKRSMGLTLAESELIKLDAERDKDRVTLEKERACAEQIVAKIEEVLMTAQAVEEDK
SSTMQYVILMYMKHLGVKVKEPRNLEHKRGRIGFLPKIKQSMKKDREGEEKGKRRGFPSI
LGPPRRPSRHDNSAIGRAMELQKQRHPKHLSTPSSVSPEPQDPAKLRQSGLASEGADAGY
LPANSTSSVVSGATLSQEGGKENDTGSKQVGETPTSGDSLDGTPRTPNTIFDFPPPPLDQ
VQEEEWEVERVTEHGTPKPFRKFDSIAFGESQSEDEQFENDLETDPPNWQQLVSREVLLG
LKPCEIKRQEVINELFYTERAHVRTLKVLDQVFYQRVSREGILSPSELRKIFSNLEDILQ
LHIGLNEQMKSVRKRNETSVIDQIGEDLLTWFSGPGEEKLKHAAATFCSNQPFALEMIKS
RQKKDSRFQTFVQDAESNPLCRRLQLKDIIPTQMQRLTKYPLLLDNIAKYTEWPMEREKV
KKAADHCRQILNYVNQAVKEAENKQRLEDYQRRLDTSNLKLSEYPNVEELRNLDLTKRKM
IHEGPLVWKVNRDKTIDLYTLLLDDILVLLQKQDDRLVLRCHSKILASTADSKHTFSPVI
KLNTVLVRQVATDNKALFVISMSDNGAQIYELVAQTVSEKTVWQDLICRMAASVKEQSTR
PIPLPESPPCEGDNDEEEPPKLKVEHHGISVTGLQSPDRDLGLESPLISSKPQSHSLGAS
GKSEVDDLFVAERQFAKEQRADGTLKEVGGNYQITIPDPHLPVSEERWALDALRNLGLLK
QLLVQQLGLTEKSTQEDWPHFPRYRTASPGAQADSGTQNSETLKAYHPGEGQMPFRTGTG
DISSCYGPRTSTESSAPQDSVVLAFQDGQASNILVMDHVIMTPEMPPAEPEGGLDESGEH
FFDAREAHSDDNPSDGDGAVKKEEKDVNLRISGNYLILDGYETVQESSTDEEIASSLPSQ
PVTGIPSVDCTHQRQHSPQNARSDGAVSPFTPEFLVQQRWGAMEDSCFEIQSPPSCADSQ
SQIMEYIHKIEADLEHLKKVEESYTILCQRLAGSALTDKHSDKS
NT seq 4635 nt   +upstreamnt  +downstreamnt
atgagtggcacacagtctaccatcaccgacaggtttcccctcaaaaaacctataaggcat
ggaagtattttgaatcgagagtcaccaacagataagaagcagaaagttgagcgcagtgca
tcacatgattttgaccccacagatagctcctccaagaagacaaagtctagttcagaggag
agtagatccgagatatatggtcttgttcaacgttgtgtgatcatccagaaggatgacaat
ggatttgggctgacggtcagtggagacaatccagtcttcgtacagtctgtcaaagaagat
ggagcagccatgcgggctggagtacagacaggtgatcgaatcatcaaggtgaatggaact
ctggtgactcattcaaaccatctggaagtggtgaagctaatcaaatctggttcctatgta
gctctcactgttcagggacgcccacctgggtcgccccagattccacttgctgattctgaa
gtagagccatcagtcattggacatatgtctcccatcatgacatccccgcattcacctgga
gcatctgggaatatggagagaattactagtcctgtgctcatgggggaggaaaacaatgtg
gttcataaccagaaagtagaaattctgagaaagatgttacagaaagaacaggaacggcta
cagttattgcaggaagattacaaccgaacacctgcccaaagattgctaaaagagatccaa
gaggccaagaaacacattcctcagctgcaagagcagttatccaaagccacaggctctgct
caggatggagctgtagttgcgtcctccaagtctttaggtgatgccctgacagtcagtgag
gtagaagcagatcctggtgacggcctaggcagaattgattatagcagtggagatgtttct
cggcacagtagtgacaatgcagatagtcccaaaagtggcctgaaagagaggatttatcta
gaggaaaacccagagaaaagtgaagtaaatcaggacattgatactcaatcactgattggg
agtccctcaacccgtatagcacctcatattattggagcagaggatgatgattttggtact
gaacatgaacagatcaatgggcaatgtagctgtttccagagcattgaactgctaaagtct
cgccctgctcacttggctgttttcttacaccatgtggtttcacagtttgaccctgcaaca
ttgctctgttatctctactcagacctgtataaacagaccaattccaaggagactcgtcgt
gtcttccttgagtttcatcagttcttcctggatcgatctgcacacctgaaagtttctgtt
cctgatgaaatatcagtagatctagacaaaagaagacctgagcttattcctgaggatcta
catcgccactatatccaaactatgcaagaaaaagtccatccagaagttcagaggcacttg
gaagattttcggcagaaacgtagcatggggctgaccttggctgaaagtgaactgattaaa
cttgatgcagagcgagacaaggaccgggtaactttggagaaggaacgggcatgtgcagag
cagattgttgccaaaattgaagaagtgctgatgactgctcaggctgtagaagaagataag
agttcgacaatgcagtatgttattctcatgtacatgaagcatttgggagtaaaagtgaaa
gaacctcgaaatttggagcacaagcggggtcggattggattccttccaaaaatcaagcaa
agtatgaagaaagatagggaaggcgaagaaaaagggaagcgaagaggattccccagcatc
ctgggacctccaaggagaccaagccgtcatgacaacagtgcaattggcagagccatggaa
ctacagaagcagcgccaccctaagcacttatccacaccctcatccgtgagtcctgaacct
caagaccctgctaagttgcgccagagtggcttagcaagtgaaggagcagacgctggatac
ctgccagccaattccacgtcgtctgtggtttcaggggccactctgtcccaggaaggaggg
aaagaaaatgatactggatcaaaacaagttggagaaacccccacatctggagactcctta
gacggcacacctcgtactcccaataccatctttgatttcccacctcctccattagaccaa
gtgcaggaggaggaatgggaagtagaaagggtgactgaacacgggacaccaaagcccttt
cgaaagtttgacagcatagcttttggagaaagtcaaagtgaggatgaacagtttgaaaat
gacttagagacagatccacccaactggcaacagctcgttagtcgggaagtgttactggga
ctaaagccttgtgagatcaaaagacaggaagtaattaatgaattgttctacactgaaaga
gctcatgttcgaacgctgaaggttcttgatcaggtcttttatcagcgagtgtccagagaa
ggaattctgtcaccttcagaactacggaaaattttttcaaacttggaagatattcttcag
cttcacattggattgaatgagcaaatgaagtctgttcgaaagaggaatgaaacttctgtt
attgatcagattggggaagatttgctgacctggttcagcggaccaggggaggagaagttg
aaacacgctgctgctaccttttgcagtaaccaaccttttgccctggaaatgatcaagtct
cgtcagaaaaaggattctagattccagacttttgtgcaagatgctgagagtaatccactg
tgtcgtcgtctacagctcaaggatatcattcccacccaaatgcagaggcttactaagtac
cctcttctattggataatattgccaaatacacagaatggccaatggaaagggagaaggtg
aagaaagctgcagatcactgtcgtcagatcttaaattatgtaaatcaggctgtcaaggag
gcagaaaacaagcagcgcttagaagattatcagcgtcgccttgatacctcgaatctgaag
ttgtcagagtacccaaatgttgaagaactcaggaatttggatttaacaaaaaggaagatg
attcatgaagggccattggtttggaaggtgaatagagataaaactattgatctatacact
ttgctgctggacgacattcttgtattgttgcaaaagcaggatgataggctggtattaagg
tgtcatagtaagattctggcatctacagctgatagcaaacacacatttagccctgtcatt
aagttgaatacagtgttggttcgacaagtggccacagataacaaagctttattcgtcatc
tccatgtcagacaatggagcccaaatttatgagctggtggcacagacagtttctgaaaag
actgtctggcaggacctaatctgtcggatggctgcatcagtgaaggagcaatccacaagg
ccaattccactgccagagtcgcccccttgcgaaggagacaatgatgaagaagaacctcca
aaactaaaagtagaacatcatggcatttcagtcactggtctgcagagtccagacagagat
ttgggattagagtctcccttaatatcgtcaaaacctcaatctcattcactgggtgcttct
gggaaatcagaggtagatgatctctttgtggctgagagacagtttgcaaaggagcaacgt
gcagatggaactctaaaggaagttggaggaaattatcaaatcacaatcccagatccacac
ttgcctgtctcagaagaacggtgggcattggatgcactaaggaatttgggtttgttgaag
cagttgctggtacaacagctgggtttgactgagaagagcactcaggaagactggccacat
ttcccaagatacaggacagcctctccaggggcacaggcagacagtggaacccagaactct
gaaactctcaaggcctatcatcctggtgaaggacagatgccctttagaactggaactggt
gacatttcatcttgttacggtccacggacttcaactgaatcttctgctccacaggattca
gtggtactggctttccaagatggccaggcaagtaacattttagtaatggaccacgtgatt
atgaccccagagatgcctcctgcagagccagaagggggtcttgatgagagtggagagcac
ttttttgatgcccgtgaagcacatagtgatgataatccatcagacggtgatggagcagtt
aaaaaggaagagaaggatgttaatttgcgcatctcaggaaactatttgatccttgacggc
tatgaaacagtgcaggagagctccacagatgaggagattgcttcctcgcttccctcgcaa
cccgtgacaggcatcccctctgtggactgtactcaccagcggcaacattctccccagaat
gctcgttctgatggggcagtttcaccgttcaccccagaattcctggtccagcagcgctgg
ggggctatggaggattcctgttttgagatccagagtcccccgtcttgtgcagattcacaa
agccagatcatggagtacattcataagatagaggctgaccttgaacacttaaagaaggtg
gaggaaagttacaccattctttgccaaaggctggctggatcggccctcacagataagcac
tcagataaaagttag

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (10)   
   KEGG PATHWAY (10)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (5)   
   RefSeq(pep) (5)   
DNA sequence (5)   
   RefSeq(nuc) (5)   
Protein domain (9)   
   Pfam (9)   
All databases (36)   

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