KEGG   Enterobacteriaceae bacterium ENNIH2: C2U52_07520
Entry
C2U52_07520       CDS       T05417                                 
Symbol
metL
Name
(GenBank) bifunctional aspartate kinase/homoserine dehydrogenase II
  KO
K12525  bifunctional aspartokinase / homoserine dehydrogenase 2 [EC:2.7.2.4 1.1.1.3]
Organism
ebc  Enterobacteriaceae bacterium ENNIH2
Pathway
ebc00260  Glycine, serine and threonine metabolism
ebc00261  Monobactam biosynthesis
ebc00270  Cysteine and methionine metabolism
ebc00300  Lysine biosynthesis
ebc01100  Metabolic pathways
ebc01110  Biosynthesis of secondary metabolites
ebc01120  Microbial metabolism in diverse environments
ebc01230  Biosynthesis of amino acids
Module
ebc_M00016  Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
ebc_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
ebc_M00018  Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:ebc00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00260 Glycine, serine and threonine metabolism
    C2U52_07520 (metL)
   00270 Cysteine and methionine metabolism
    C2U52_07520 (metL)
   00300 Lysine biosynthesis
    C2U52_07520 (metL)
  09110 Biosynthesis of other secondary metabolites
   00261 Monobactam biosynthesis
    C2U52_07520 (metL)
Enzymes [BR:ebc01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.3  homoserine dehydrogenase
     C2U52_07520 (metL)
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.2  Phosphotransferases with a carboxy group as acceptor
    2.7.2.4  aspartate kinase
     C2U52_07520 (metL)
SSDB
Motif
Pfam: Homoserine_dh AA_kinase NAD_binding_3
Other DBs
NCBI-ProteinID: AUV06133
Position
complement(1146374..1148806)
AA seq 810 aa
MSVNAQAGAKVRQLHKFGGSSLADVKCYLRVAGIMAEYSQPGDLMVVSAAGSTTNQLISW
LKLSQTDRLSAHQVQQSLRRYQSELIAGLLSPEVADGLISEFIRDLERLAGLLDGGITDA
VYAEVVGHGEVWSARLMSAVLNQQGQASAWLDAREFLRAERAAQPQVNEGASWPLFQQLL
AQHPDKRIVVTGFISRNEAGETVLLGRNGSDYSATQIGALAGVTRVTIWSDVAGVYSADP
RKVKDACLLPLLRLDEASELARLAAPVLHARTLQPVSGSNIDLQLRCSYNPEQGSTRIER
VLASGTGARIVTSHDDVCLIEFQVPAGQDFKLAQRDIDVILKRAQVRPLATGAHADRNLL
QLCYTSEVVDSVFKLLDEAGLPGELRLRQGLALVALVGAGVCRNPLHSHRFWQQLKGQAV
EFVWQSDEGISLVAVLRVGPTESLIQGLHQSLFRAEKRIGLMLFGKGNIGSRWLELFARE
QSALSARTGFEFVLAGVVDSRRSLLNYDGLDASRALAFFNDEAVEQEEEALFLWMRAHPY
DDLVVLDVTASPQLADQYLDFASHGFHVISANKLAGASSSNKYRQIHDAFEKTGRRWLYN
ATVGAGLPVNHTVRDLIDSGDSILAISGIFSGTLSWLFLQFDGTVPFTDLVDQAWQQGLT
EPDPRVDLSGKDVMRKLVILAREAGYDIEPDHVRVESLVPTSCEEESIDHFFENGDELNE
QMTQRLEAAREMGLVLRYVARFDANGKARVGVEAVRPEHPLAALLPCDNVFAIESRWYRD
NPLVIRGPGAGRDVTAGAIQSDINRLAQLL
NT seq 2433 nt   +upstreamnt  +downstreamnt
atgagtgtgaatgcgcaggcaggggcgaaggttcgtcaactgcataagtttggtgggagc
agtctggctgatgtgaaatgttacctgcgcgtcgcggggatcatggcggaatattcgcaa
ccgggcgatttgatggtcgtttcggcagcaggcagtaccactaaccagttgattagctgg
cttaaattgagccagaccgatcgtctctctgcgcatcaggttcaacagtcgttacgtcgt
taccagagcgagctgattgccgggttgttgtcaccggaggtggctgatggcctgattagc
gagtttattcgtgacctcgagcgcctggccgggttgctggacggtggcattaccgatgcg
gtctacgccgaagtggtggggcatggggaagtgtggtctgcgcgtctgatgtctgccgta
ctgaatcagcaagggcaagcgtcggcatggcttgatgcgcgcgagtttctgcgcgcggaa
cgcgcggcacagccgcaggtcaacgaaggcgcctcctggccgctgttccagcaactgctg
gcgcagcatccggataaacgtatcgttgtgacgggctttatcagccgtaacgaggcgggc
gaaaccgtactgttggggcgtaatggttctgactattcggcaacgcaaattggcgcatta
gccggtgttacccgcgtgacgatctggagcgacgtggccggggtgtacagcgccgacccg
cgtaaagtgaaagatgcctgcctgctgcctctgctgcgtctggatgaagccagcgagctg
gcccgtctggcagcacctgtactccacgcccgaaccctacagccggtatccggcagtaat
atcgatttgcagttgcgttgtagctataacccggagcagggttccacgcgtattgagcgc
gtactggcatctggcacgggtgcccgcatcgtcaccagtcatgatgatgtctgtctgatc
gagtttcaggtccctgccgggcaagatttcaaactggcgcaacgtgatatagatgtgatc
ctcaagcgcgctcaggttcgtccgctggcgacaggcgcgcacgctgaccgtaatttgctg
caactctgctacacctcggaagtggtggatagcgtctttaaactgctcgacgaagccggt
ctgccgggcgagttgcgtttacgtcaggggctggcgctggtggcgctggtcggggcgggc
gtttgccgtaatccgttgcacagccaccgtttctggcaacaattgaaaggtcaggccgtg
gaattcgtctggcagtcagatgaggggatcagccttgttgccgtgctgcgcgtggggcca
acggaaagtctgattcaggggctgcaccagtcactgttccgcgcggaaaaacgcattggc
ctgatgttgtttggtaaaggcaatattggttctcgctggctggaactgtttgcccgcgaa
cagagcgcgctgtctgctcgtaccgggttcgaatttgttctcgcaggggtggtggatagc
cgccgcagcttgttgaattacgatggtctcgacgccagccgggcgctggccttcttcaat
gatgaggcggtcgagcaggaggaagaggcgctatttctgtggatgcgcgcgcacccgtac
gatgatctggtggtgctggatgtcaccgcgagcccgcagcttgccgaccagtatctggat
ttcgccagccacggttttcatgtgatcagtgccaataaactggctggtgccagcagcagt
aataaataccgccagatccacgacgcatttgaaaaaaccggacgtcgctggttgtataac
gccaccgttggggccgggttgccggtaaaccatacggtgcgcgatcttatcgacagcggc
gacagtattctggccatcagtggtatcttctccggtacgctctcctggttgttcctgcaa
tttgatggcaccgtgccgtttaccgacctggtcgatcaggcctggcagcagggattgacc
gagcccgacccgcgcgtcgatctctccggtaaagatgtgatgcgtaagctggtcattctg
gcgcgtgaggcaggctatgacatcgagccagaccacgtgcgcgtggagtccctggtgccg
acgagctgtgaagaagagtctatcgaccacttctttgagaatggcgatgagctgaatgag
caaatgacacagcgtctggaagccgctcgcgagatgggactggtgctgcgttatgtggcg
cgttttgatgccaacggcaaagcgcgtgtgggtgtggaagcggtgcgtccggaacatccg
ctggcggcactgctgccttgcgacaatgtgtttgccatcgaaagccgctggtatcgcgat
aacccgctggtgatccgtgggccgggagccggtcgtgatgtcactgccggcgcaattcag
tcggatatcaaccgcctggcgcagttgctgtag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (13)   
   KEGG PATHWAY (8)   
   KEGG MODULE (5)   
Chemical substance (11)   
   KEGG COMPOUND (11)   
Chemical reaction (5)   
   KEGG ENZYME (2)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein domain (3)   
   Pfam (3)   
All databases (38)   

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